Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Valerie Schrott"'
Autor:
Johannes-Peter Stasch, Tim Bachman, Eva-Maria Becker-Pelster, Matthias Beat Wittwer, Grant C. Bullock, Scott A. Hahn, Hubert Truebel, Mark T. Gladwin, Grace M Mallampalli, Katherine C. Wood, Valerie Schrott, Jeffrey J. Baust, Ilka Mathar, Karin P. Potoka, Jan Stampfuss, Peter Sandner, Adam C. Straub, Ana L. Mora, Marta Bueno, Bin Sun, David O. Osei-Hwedieh, Rebecca Vanderpool
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 58:636-647
Sickle cell disease (SCD) is associated with intravascular hemolysis and oxidative inhibition of nitric oxide (NO) signaling. BAY 54-6544 is a small-molecule activator of oxidized soluble guanylate cyclase (sGC), which, unlike endogenous NO and the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fc694b150d885c6ed1df2b209d6639f
https://doi.org/10.1165/rcmb.2017-0292oc
https://doi.org/10.1165/rcmb.2017-0292oc
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Anemia is a very common blood disorder that affects the lives of billions of people worldwide. Anemia is caused by the loss of blood, increased destruction of red blood cells (RBCs), or reduced production of RBCs. Erythropoiesis is the complex proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0118f003e1ab257952a6aab96ef5857e
https://pubmed.ncbi.nlm.nih.gov/29101126
https://pubmed.ncbi.nlm.nih.gov/29101126
Autor:
Yingze Zhang, Mark T. Gladwin, Jing Zhao, Yutong Zhao, Valerie Schrott, Jianxin Wei, Grant C. Bullock
Interleukin-33 (IL-33) is a member of the IL-1 cytokine superfamily that potently drives production of a variety of cytokines and contributes to the pathogenesis of inflammatory diseases. The IL-33 is a nuclear protein and is released from apoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c46e91e8ab4c29c126fee8a77b6863
https://europepmc.org/articles/PMC4767276/
https://europepmc.org/articles/PMC4767276/
Autor:
Naomi D Gunawardena, Sruti Shiva, Catherine Corey, Grant C. Bullock, Yinna Wang, Valerie Schrott, Teague Nolan Cole, Chanté L. Richardson
Publikováno v:
Blood. 128:74-74
Anemia is a global health problem that decreases quality of life for billions of people. Previous studies have concluded that there is an iron-regulated checkpoint in erythropoiesis that suppresses red blood cell production. This results in anemia an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1760c415aeeb369ef97c6934b48398ea
https://doi.org/10.1182/blood.v128.22.74.74
https://doi.org/10.1182/blood.v128.22.74.74
Autor:
Maria G. Kapetanaki, Solomon F. Ofori-Acquah, Gregory J. Kato, Grant C. Bullock, Deva Sharma, Valerie Schrott, Frances Weidart, Oluwabukola T. Gbotosho
Publikováno v:
Blood. 126:403-403
Patients with sickle cell disease (SCD) have elevated plasma levels of placenta growth factor (PlGF) which promotes expression of the pulmonary vasoconstrictor endothelin-1 (ET-1) contributing to pulmonary hypertension, an important age-related and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37055a5d0952603e28e7a97b36762fa
https://doi.org/10.1182/blood.v126.23.403.403
https://doi.org/10.1182/blood.v126.23.403.403
Autor:
Grant C. Bullock, Teague Nolan Cole, Chanté L. Richardson, Catherine Corey, Sruti Shiva, Valerie Schrott, Naomi D Gunawardena
Publikováno v:
Blood. 126:2145-2145
Several clinical observations illustrate the link between iron and erythropoietin (EPO)-mediated signaling in committed erythroid progenitor cells. In iron deficiency anemia (IDA), erythropoiesis is blocked despite increased serum EPO concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab16458af1b615f9580383b4cb4192fe
https://doi.org/10.1182/blood.v126.23.2145.2145
https://doi.org/10.1182/blood.v126.23.2145.2145
Autor:
Yinna Wang, Catherine Corey, Sruti Shiva, Valerie Schrott, Chanté L Richardson, Grant C. Bullock, Claudette M. St. Croix
Publikováno v:
Blood. 124:216-216
Iron and erythropoietin (Epo) are intimately linked regulators of erythropoiesis. Moderate iron restriction suppresses erythropoiesis at the Epo-dependent, CFU-E stage, without induction of apoptosis and without suppression of other hematopoietic cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3a44802422b49ee0dd4185cbdc0907b
https://doi.org/10.1182/blood.v124.21.216.216
https://doi.org/10.1182/blood.v124.21.216.216
Autor:
Valerie Schrott, Grant C. Bullock, Tamir Kanias, Enrico M. Novelli, Donna B. Stolz, Jeffrey S. Isenberg
Publikováno v:
Blood. 124:4068-4068
Thrombospondin-1 (TSP1) is a secreted matricellular protein found preformed in platelet α-granules and upregulated in the plasma of patients with sickle cell disease (SCD). In preclinical models TSP1 enhances sickle red blood cell (RBC) binding to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57994c4cdbe941f5a82f77d172aa900a
https://doi.org/10.1182/blood.v124.21.4068.4068
https://doi.org/10.1182/blood.v124.21.4068.4068
Autor:
Valerie Schrott, Grant C. Bullock
Publikováno v:
Blood. 122:3443-3443
Several clinical observations illustrate the link between iron and erythropoietin (Epo)-mediated signaling in early erythroid progenitor cells. In iron deficiency anemia (IDA) erythropoiesis is blocked at an early stage despite increased serum Epo co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f74891300e20781a78747a972775e2ad
https://doi.org/10.1182/blood.v122.21.3443.3443
https://doi.org/10.1182/blood.v122.21.3443.3443
Autor:
Arunava Manna, Rita Mihailescu, Rebecca Barnard, Damian S. McAninch, Danith H. Ly, Valerie Schrott
Publikováno v:
Biophysical Journal. 104:264a
microRNA-122 (miR-122), a liver specific microRNA, has been shown to facilitate the Hepatitis C virus (HCV) replication and/or translation. Although the exact role played by miR-122 in this process is not fully understood, it has been shown that one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236800789cf540f4653e02fe28c2fa13
https://doi.org/10.1016/j.bpj.2012.11.1482
https://doi.org/10.1016/j.bpj.2012.11.1482