Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Valerie P. Wright"'
Autor:
Dharti Shantaram, Rebecca Hoyd, Alecia M. Blaszczak, Linda Antwi, Anahita Jalilvand, Valerie P. Wright, Joey Liu, Alan J. Smith, David Bradley, William Lafuse, YunZhou Liu, Nyelia F. Williams, Owen Snyder, Caroline Wheeler, Bradley Needleman, Stacy Brethauer, Sabrena Noria, David Renton, Kyle A. Perry, Prabha Nagareddy, Daniel Wozniak, Sahil Mahajan, Pranav S. J. B. Rana, Maciej Pietrzak, Larry S. Schlesinger, Daniel J. Spakowicz, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from individuals with obesity contains more neutrophils than in those without obesity and is associated
Externí odkaz:
https://doaj.org/article/9193f2df0d714844a1ba35b032ffb441
Publikováno v:
International Journal of Qualitative Methods, Vol 22 (2023)
Mainland Chinese born in the 1940s–1950s have experienced unique socio-cultural circumstances that have shaped their late-life immigration experiences. Little is known about what this population perceives would reduce their loneliness. This study a
Externí odkaz:
https://doaj.org/article/18b5be76460f4129a4b034ee31e7394d
Autor:
Alecia M. Blaszczak, Anahita Jalilvand, Joey Liu, Valerie P. Wright, Andrew Suzo, Bradley Needleman, Sabrena Noria, William Lafuse, Willa A. Hsueh, David Bradley
Publikováno v:
Journal of Diabetes Research, Vol 2019 (2019)
Obesity is associated with a state of chronic low-grade inflammation both systemically and within specific tissues, including adipose tissue (AT). In murine models of obesity, there is a shift in the inflammatory profile of the AT immune cells, with
Externí odkaz:
https://doaj.org/article/7fc0f253207240ba9a11ba6d6cc1bd80
Autor:
DHARTI SHANTARAM, ALECIA M. BLASZCZAK, REBECCA HOYD, ALAN SMITH, LINDA ANTWI, JOEY Z. LIU, VALERIE P. WRIGHT, DAVID BRADLEY, YUNZHOU LIU, NYELIA F. WILLIAMS, DAN SPAKOWICZ, WILLA HSUEH
Publikováno v:
Diabetes. 71
Neutrophils protect against invading bacteria, and their unique role in adipose tissue inflammation and insulin resistance (IR) in obesity is increasingly recognized. We found that visceral adipose tissue (VAT) of obese (n=83) compared to lean (n=13)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bdc5897e27b5917093c8ddfd3577fbb
https://doi.org/10.2337/db22-1417-p
https://doi.org/10.2337/db22-1417-p
Autor:
Gina S. Torres Matias, Valerie P. Wright, Alecia Blaszczak, Willa A. Hsueh, David Bradley, William E. Carson, Dionisia Quiroga, Joey Liu, Lianbo Yu, Anahita Jalilvand
Publikováno v:
Surg Oncol
Background Adipose tissue has emerged as an important window into cancer pathophysiology, revealing potential targets for novel therapeutic interventions. The goal of this study was to compare the breast adipose tissue (BrAT) immune milieu surroundin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ce8c35b5d5f639fc5d19defaaf522d
https://europepmc.org/articles/PMC8671189/
https://europepmc.org/articles/PMC8671189/
Autor:
Valerie P. Wright, Sarah M. Nicoloro, Joey Liu, Kajol Anandani, Michael P. Czech, Tuo Deng, Anahita Jalilvand, Alecia Blaszczak, William P. Lafuse, David Bradley, Willa A. Hsueh, Stephen M. Bergin
Publikováno v:
The Journal of Immunology. 202:2451-2459
Macrophages, B cells, and adipocytes are among the adipose tissue (AT) APCs that differentiate and activate naive CD4+ T cells. Mice with adipocyte loss of MHC class II (MHC II) are more insulin sensitive. Because macrophages are professional APCs, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c614b57ae6250e612da907b855b77
https://doi.org/10.4049/jimmunol.1801470
https://doi.org/10.4049/jimmunol.1801470
Autor:
Stephen M. Bergin, Willa A. Hsueh, Anahita Jalilvand, Árpád Somogyi, Joey Liu, Matt Bernier, Valerie P. Wright, David C. Bradley, Kajol Anandani, Alecia Blaszczak, Vicki H. Wysocki, Gina Gebhardt
Publikováno v:
Immunometabolism
Background: Obesity is characterized by visceral adipose tissue (AT) inflammation. Immunosuppressive regulatory T cells (Tregs), phagocytic M2-like macrophages, and innate lymphoid cells type 2 (ILC2) control lean AT inflammation to maintain systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b29176f88f82e050025bd7d477103d
https://pubmed.ncbi.nlm.nih.gov/32774894
https://pubmed.ncbi.nlm.nih.gov/32774894
Autor:
Jae Cheon Ryu, David C. Bradley, Rawan Tarawneh, Valerie P. Wright, Alecia Blaszczak, Joey Z. Liu, Yuxi Liu, Willa A. Hsueh, Sung Ok Yoon
Publikováno v:
Diabetes. 69
Background: Obesity heightens the risk for both cardiometabolic complications and Alzheimer’s disease (AD). Although the reasons have yet to be fully elucidated, weight loss improves cognition. Given this link, factors overproduced by obese adipose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc9d7d542c5434f7b02bab130f6b4674
https://doi.org/10.2337/db20-2010-p
https://doi.org/10.2337/db20-2010-p
Autor:
Sabrena Noria, Willa A. Hsueh, Anahita Jalilvand, Alecia Blaszczak, David C. Bradley, Kathleen Wyne, Joshua J. Joseph, Valerie P. Wright, Alan L. Smith, Joey Z. Liu
Publikováno v:
Diabetes. 69
Background: AT Tregs are decreased in obese mice. We have previously shown that preventing this decline improves insulin sensitivity, despite persistent obesity, underscoring a key role for AT Tregs in systemic metabolism. Therefore, we sought to exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd652bc6a4decd033244a24e1822006
https://doi.org/10.2337/db20-1675-p
https://doi.org/10.2337/db20-1675-p
Autor:
Kajol Anandani, Joshua J. Joseph, Valerie P. Wright, Stephen T. C. Wong, Willa A. Hsueh, David Renton, Bradley Needleman, Sabrena Noria, Alecia Blaszczak, Martha Yearsley, Joey Liu, David Bradley, Zheng Yin
Publikováno v:
Diabetes Care. 42:466-475
OBJECTIVE Components of the adipose tissue (AT) extracellular matrix (ECM) are recently discovered contributors to obesity-related cardiometabolic disease. We identified increased adipocyte expression of ECM-related clusterin (apolipoprotein J) in ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2577e72e5d82e52bc189645ee73dcdc6
https://doi.org/10.2337/dc18-0870
https://doi.org/10.2337/dc18-0870