Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Valerie P O'Brien"'
Autor:
Kavita Agarwal, Lloyd S Robinson, Somya Aggarwal, Lynne R Foster, Ariel Hernandez-Leyva, Hueylie Lin, Brett A Tortelli, Valerie P O'Brien, Liza Miller, Andrew L Kau, Hilary Reno, Nicole M Gilbert, Warren G Lewis, Amanda L Lewis
Publikováno v:
PLoS Biology, Vol 18, Iss 8, p e3000788 (2020)
Women with bacterial vaginosis (BV), an imbalance of the vaginal microbiome, are more likely to be colonized by potential pathogens such as Fusobacterium nucleatum, a bacterium linked with intrauterine infection and preterm birth. However, the condit
Externí odkaz:
https://doaj.org/article/b43f4f413fa64ae5b5d56ce5f62edb0d
Autor:
Lu Yu, Valerie P O'Brien, Jonathan Livny, Denise Dorsey, Nirmalya Bandyopadhyay, Marco Colonna, Michael G Caparon, Elisha DO Roberson, Scott J Hultgren, Thomas J Hannan
Publikováno v:
eLife, Vol 8 (2019)
A mucosal infectious disease episode can render the host either more or less susceptible to recurrent infection, but the specific mechanisms that tip the balance remain unclear. We investigated this question in a mouse model of recurrent urinary trac
Externí odkaz:
https://doaj.org/article/b0c8e96f899e42328c14402806c5bb7b
Autor:
Valerie P O'Brien, Nicole M Gilbert, Tania Lebratti, Kavita Agarwal, Lynne Foster, Haina Shin, Amanda L Lewis
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219941 (2019)
Escherichia coli infection of the female reproductive tract is a significant cause of disease in humans and animals, but simple animal models are lacking. Here we report that vaginal inoculation of uropathogenic E. coli strains UTI89 and CFT073 in no
Externí odkaz:
https://doaj.org/article/6725de99779d46819db84f483a12ea6a
Publikováno v:
PLoS Pathogens, Vol 14, Iss 12, p e1007457 (2018)
Urinary tract infections (UTI) are extremely common and can be highly recurrent, with 1-2% of women suffering from six or more recurrent episodes per year. The high incidence of recurrent UTI, including recurrent infections caused by the same bacteri
Externí odkaz:
https://doaj.org/article/94aca2b4f8284e16befb101cb9ad53d0
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006238 (2017)
Pathogens often inhabit the body asymptomatically, emerging to cause disease in response to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are regarded as likely origins of recurrent urinary tract infection (rUTI),
Externí odkaz:
https://doaj.org/article/c0d3776eaa1f4efca04139b7469d25e8
Autor:
Seongmi K. Russell, Jessica K. Harrison, Benjamin S. Olson, Hyung Joo Lee, Valerie P. O’Brien, Xiaoyun Xing, Jonathan Livny, Lu Yu, Elisha D. O. Roberson, Rajdeep Bomjan, Changxu Fan, Marina Sha, Shady Estfanous, Amal O. Amer, Marco Colonna, Thaddeus S. Stappenbeck, Ting Wang, Thomas J. Hannan, Scott J. Hultgren
Publikováno v:
Nature Microbiology. 8:875-888
Previous urinary tract infections (UTIs) can predispose one to future infections; however, the underlying mechanisms affecting recurrence are poorly understood. We previously found that UTIs in mice cause differential bladder epithelial (urothelial)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4faeea41dd8a9df4355998246b870e1a
https://doi.org/10.1038/s41564-023-01346-6
https://doi.org/10.1038/s41564-023-01346-6
Autor:
Valerie P. O’Brien, Yuqi Kang, Meera K. Shenoy, Greg Finak, William C. Young, Julien Dubrulle, Lisa Koch, Armando E. Rodriguez Martinez, Jazmine A. Snow, Jeffery Williams, Elizabeth Donato, Surinder K. Batra, Cecilia C.S. Yeung, Susan Bullman, Meghan A. Koch, Raphael Gottardo, Nina R. Salama
Mechanisms forHelicobacter pylori(Hp)-driven stomach cancer are not fully understood. In a transgenic mouse model of gastric preneoplasia, concomitantHpinfection and induction of constitutively active KRAS (Hp+KRAS+) alters metaplasia phenotypes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1fc21591ef9fdaad8f1713d12a7cd4
https://doi.org/10.1101/2022.12.20.521287
https://doi.org/10.1101/2022.12.20.521287
Autor:
Nicole M. Gilbert, Valerie P. O’Brien, Chevaughn Waller, Ekatherina Batourina, Cathy Lee Mendelsohn, Amanda L. Lewis
Publikováno v:
Frontiers in Cellular and Infection Microbiology. 12
The anaerobic actinobacterium Gardnerella was first isolated from the bladder by suprapubic aspiration more than 50 years ago. Since then, Gardnerella has been increasingly recognized as a common and often abundant member of the female urinary microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc4e98b9f425aaf95df4626c6325095d
https://doi.org/10.3389/fcimb.2022.909799
https://doi.org/10.3389/fcimb.2022.909799
Bladder Exposure to Gardnerella Activates Host Pathways Necessary for Escherichia coli Recurrent UTI
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Recurrent urinary tract infections (rUTI) are a costly clinical problem affecting millions of women worldwide each year. The majority of rUTI cases are caused by uropathogenic Escherichia coli (UPEC). Data from humans and mouse models indicate that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a16057ea6e289caa7f814c70039eecf
https://doi.org/10.3389/fcimb.2021.788229
https://doi.org/10.3389/fcimb.2021.788229
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Recurrent urinary tract infections (rUTI) are a costly clinical problem affecting millions of women worldwide each year. The majority of rUTI cases are caused by uropathogenic Escherichia coli (UPEC). Data from humans and mouse models indicate that s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd5e388967fbfb7dc2e84d7c33cbbc35
https://pubmed.ncbi.nlm.nih.gov/34938672
https://pubmed.ncbi.nlm.nih.gov/34938672