Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valerie M. Merkle"'
Publikováno v:
Extreme Mechanics Letters. 7:18-26
Deformation-induced mechanical and structural anisotropy has been analyzed using a gelatin film model. Specifically, gelatin films cast from water and 2,2,2-trifluoroethanol (TFE) are stretched at various draw ratios, locked-in the extended conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe4460a05d1d0b012c221a1b16e5a03
https://doi.org/10.1016/j.eml.2016.02.010
https://doi.org/10.1016/j.eml.2016.02.010
Publikováno v:
Biopolymers. 101:336-346
Coaxial electrospinning is used to fabricate nanofibers with gelatin in the shell and polyvinyl alcohol (PVA) in the core in order to derive mechanical strength from PVA and bioactivity from gelatin. At a 1:1 PVA/gelatin mass ratio, the core-shell na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e4210c227fac92fc1e1721d2d518e25
https://doi.org/10.1002/bip.22367
https://doi.org/10.1002/bip.22367
Publikováno v:
Polymer. 54:6003-6007
In this study, polyvinyl alcohol (PVA) and gelatin are coaxially electrospun into core–shell nanofibers to derive mechanical strength from PVA and bioactivity from gelatin. The core–shell nanofibers with PVA in the core and gelatin in the shell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3794e9187b49b8020986d065ba8a684f
https://doi.org/10.1016/j.polymer.2013.08.056
https://doi.org/10.1016/j.polymer.2013.08.056
Autor:
Valerie M. Merkle, Katrina J. DeCook, Kaitlyn R. Ammann, Phat L. Tran, Pak Kin Wong, Marvin J. Slepian
Publikováno v:
Journal of Biological Engineering
Background Cell migration is a vital process for growth and repair. In vitro migration assays, utilized to study cell migration, often rely on physical scraping of a cell monolayer to induce cell migration. The physical act of scrape injury results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a105d99487009cad9fc3037a87c61fa0
https://doi.org/10.1186/s13036-015-0015-y
https://doi.org/10.1186/s13036-015-0015-y
Autor:
Kaitlyn R. Ammann, Xiaoyi Wu, Marcus Hutchinson, Phat L. Tran, Katrina J. DeCook, Marvin J. Slepian, Valerie M. Merkle
Publikováno v:
Acta biomaterialia. 27
Cardiovascular disease is the leading cause of death in the world. In this study, coaxial electrospinning is employed to fabricate fibers in a core–shell structure with polyvinyl alcohol (PVA) in the core and gelatin in the shell for evaluation as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70feb01fbc7110a3b9a5ff2176f6d234
https://pubmed.ncbi.nlm.nih.gov/26320540
https://pubmed.ncbi.nlm.nih.gov/26320540
Autor:
Marvin J. Slepian, Valerie M. Merkle, Kaitlyn R. Ammann, Katrina J. DeCook, Phat L. Tran, Xiaoyi Wu
Publikováno v:
Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments.
Coaxial electrospinning is a novel technique that allows the fabrication of composite nanofibers in a core-shell structure. This technique can be used to optimize the biological properties of a natural polymer (i.e. gelatin) and the mechanical proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99b43d70598ad332137fe205095dc18e
https://doi.org/10.1115/sbc2013-14790
https://doi.org/10.1115/sbc2013-14790
Autor:
Marvin J. Slepian, Marcus Hutchinson, Xiaoyi Wu, Jawaad Sheriff, Phat L. Tran, Valerie M. Merkle, Danny Bluestein
Publikováno v:
Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments.
A biocompatible scaffold is vital to implant device design, tissue engineering, and drug delivery. Previous work has shown smooth muscle cell and human umbilical vascular endothelial cell viability, adhesion, proliferation, and migration on coaxially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abef929084c315a37b179471e6e3e6ca
https://doi.org/10.1115/sbc2013-14780
https://doi.org/10.1115/sbc2013-14780
Autor:
Tracy DeCook, Marvin J. Slepian, Phat L. Tran, Valerie M. Merkle, Jawaad Sheriff, Danny Bluestein, Marcus Hutchinson
Publikováno v:
Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments.
Mechanical circulatory support (MCS) devices, such as the total artificial heart and ventricular assist devices, are employed as bridge-to-transplant or destination therapies for advanced heart failure.[1] Recipients of these life-saving MCS devices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f35ec9f954601ce6180a0f211644f454
https://doi.org/10.1115/sbc2013-14825
https://doi.org/10.1115/sbc2013-14825
Publikováno v:
Biopolymers. 101(4)
Coaxial electrospinning is used to fabricate nanofibers with gelatin in the shell and polyvinyl alcohol (PVA) in the core in order to derive mechanical strength from PVA and bioactivity from gelatin. At a 1:1 PVA/gelatin mass ratio, the core-shell na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cc9d49cdef276f807a361a99b619efd
https://pubmed.ncbi.nlm.nih.gov/23913748
https://pubmed.ncbi.nlm.nih.gov/23913748
Autor:
Valerie M. Merkle, Xiaoyi Wu
Publikováno v:
2012 38th Annual Northeast Bioengineering Conference (NEBEC).
Electrospinning has been used to fabricate nanofibrous scaffolds from a variety of synthetic and natural materials, including polyvinyl alcohol (PVA) and gelatin. Although PVA possesses appealing mechanical properties for tissue engineering applicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac156036c0c3baa0b5fa54d1dcd8817
https://doi.org/10.1109/nebc.2012.6207123
https://doi.org/10.1109/nebc.2012.6207123