Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Valerie Lecureur"'
Autor:
Alain Lescoat, Riccardo Leinardi, Kevin Pouxvielh, Yousof Yacoub, Marie Lelong, Amandine Pochet, Erwan Dumontet, Nessrine Bellamri, Erwan Le Tallec, Cristina Pavan, Francesco Turci, Christophe Paris, François Huaux, valerie Lecureur
Although epidemiological studies have suggested an association between asbestos exposure and systemic autoimmunity, the underlying mechanisms are poorly understood. Short asbestos fibers are often considered less harmful than long fibers but such a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e3914139feb588ac17c00a11c40f82
https://doi.org/10.21203/rs.3.rs-2504079/v1
https://doi.org/10.21203/rs.3.rs-2504079/v1
Autor:
Erwan Le Tallec, Nessrine Bellamri, Marie Lelong, Claudie Morzadec, Quentin Frenger, Alice Ballerie, Claire Cazalets, Alain Lescoat, Frédéric Gros, Valérie Lecureur
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSystemic sclerosis (SSc) is an autoimmune disease characterized by antinuclear antibody production, which has been linked to an excess of apoptotic cells, normally eliminated by macrophages through efferocytosis. Additionally, circulating
Externí odkaz:
https://doaj.org/article/7927b447f89744eb8b44b33d3fa2133e
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Crystalline silica (cSiO2) is a mineral found in rocks; workers from the construction or denim industries are particularly exposed to cSiO2 through inhalation. cSiO2 inhalation increases the risk of silicosis and systemic autoimmu
Externí odkaz:
https://doaj.org/article/25d5578767884abf9c34679374759458
Autor:
Gerard P. Zambetti, Erin G. Schuetz, John D. Schuetz, Daxi Sun, Valerie Lecureur, Jaideep V. Thottassery, Jill M. Lahti
Publikováno v:
Oncogene. 20:303-313
The mdr1b gene is thought to be a "stress-responsive" gene, however it is unknown if this gene is regulated by p53 in the whole animal. Moreover, it is unknown if overexpression of mdr1b affects cell survival. The dependence of mdr1b upon p53 for upr
Autor:
Erin G. Schuetz, Jatinder K. Lamba, John D. Schuetz, Frank J. Gonzalez, Richard B. Kim, Raman Venkataramanan, Cynthia Brimer, Stephen C. Strom, Valerie Lecureur, Christopher J. Sinal, Hongbo Cai, Mahfoud Assem, Kazuto Yasuda, Vinod Ramachandran, Bernard J. Komoroski
Publikováno v:
The Journal of biological chemistry. 276(42)
Sister of P-glycoprotein (SPGP) is the major hepatic bile salt export pump (BSEP). BSEP/SPGP expression varies dramatically among human livers. The potency and hierarchy of bile acids as ligands for the farnesyl/bile acid receptor (FXR/BAR) parallele
Autor:
Alain Lescoat, Alice Ballerie, Marie Lelong, Yu Augagneur, Claudie Morzadec, Stéphane Jouneau, Patrick Jégo, Olivier Fardel, Laurent Vernhet, Valérie Lecureur
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Inhalation of crystalline silica (SiO2) is a risk factor of systemic autoimmune diseases such as systemic sclerosis (SSc) and fibrotic pulmonary disorders such as silicosis. A defect of apoptotic cell clearance (i.e., efferocytosis, a key process in
Externí odkaz:
https://doaj.org/article/fe6e52dfef2c4624bcd6a83f7553a292
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0116560 (2015)
Macrophages (MΦ), well-known to play an important role in immune response, also respond to environmental toxic chemicals such as diesel exhaust particles (DEP). Potential effects of DEPs towards MΦ polarization, a key hall-mark of MΦ physiology, r
Externí odkaz:
https://doaj.org/article/a0b357431e5a4d22a4745164761f5d53
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121232 (2015)
Diesel exhaust particles (DEPs) are common environmental air pollutants primarily affecting the lung. DEPs or chemicals adsorbed on DEPs also exert extra-pulmonary effects, including alteration of hepatic drug detoxifying enzyme expression. The prese
Externí odkaz:
https://doaj.org/article/a2a4697e4be04c62906058f7bd7fd2c3
Autor:
Karin Simonin-Le Jeune, André Le Jeune, Stéphane Jouneau, Chantal Belleguic, Pierre-François Roux, Marie Jaguin, Marie-Thérèse Dimanche-Boitre, Valérie Lecureur, Caroline Leclercq, Benoît Desrues, Graziella Brinchault, Jean-Pierre Gangneux, Corinne Martin-Chouly
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75667 (2013)
BACKGROUND: Early in life, cystic fibrosis (CF) patients are infected with microorganisms. The role of macrophages has largely been underestimated in literature, whereas the focus being mostly on neutrophils and epithelial cells. Macrophages may howe
Externí odkaz:
https://doaj.org/article/cdf1d65f67bc4284b3bb8ddfbbc99523