Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Valerie Kuan"'
Publikováno v:
Cardio-Oncology, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract Background There is substantial evidence that systemic anticancer therapies and radiotherapy can increase the long-term risk of cardiovascular disease (CVD). Optimal management decisions for cancer patients therefore need to take into accoun
Externí odkaz:
https://doaj.org/article/358b64320ca44fb4a05ad96a3040439f
Autor:
Harry Hemingway, Riyaz Patel, Joan K Morris, Aroon D Hingorani, Reecha Sofat, Claudia Langenberg, Nicholas J Wald, Valerie Kuan, Chris Finan, Jasmine Gratton, A Floriaan Schmidt
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To clarify the performance of polygenic risk scores in population screening, individual risk prediction, and population risk stratification.Design Secondary analysis of data in the Polygenic Score Catalog.Setting Polygenic Score Catalog, Ap
Externí odkaz:
https://doaj.org/article/c69e54411b7f40da9fe90317bc2b73ca
Autor:
Anoop D Shah, Anuradhaa Subramanian, Jadene Lewis, Samir Dhalla, Elizabeth Ford, Shamil Haroon, Valerie Kuan, Krishnarajah Nirantharakumar
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0290583 (2023)
BackgroundLong Covid is a widely recognised consequence of COVID-19 infection, but little is known about the burden of symptoms that patients present with in primary care, as these are typically recorded only in free text clinical notes.AimsTo compar
Externí odkaz:
https://doaj.org/article/c0f76ef3f9c94003b2dc9421929fe655
Autor:
Valerie Kuan, Helen C. Fraser, Melanie Hingorani, Spiros Denaxas, Arturo Gonzalez-Izquierdo, Kenan Direk, Dorothea Nitsch, Rohini Mathur, Constantinos A. Parisinos, R. Thomas Lumbers, Reecha Sofat, Ian C. K. Wong, Juan P. Casas, Janet M. Thornton, Harry Hemingway, Linda Partridge, Aroon D. Hingorani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Reducing the burden of late-life morbidity requires an understanding of the mechanisms of ageing-related diseases (ARDs), defined as diseases that accumulate with increasing age. This has been hampered by the lack of formal criteria to ident
Externí odkaz:
https://doaj.org/article/a4cfa63aeff54b99ac644b906f56e8bb
Autor:
Amal R Khanolkar, Nishi Chaturvedi, Valerie Kuan, Daniel Davis, Alun Hughes, Marcus Richards, David Bann, Praveetha Patalay
Publikováno v:
PLoS Medicine, Vol 18, Iss 9, p e1003775 (2021)
BackgroundWe aimed to estimate multimorbidity trajectories and quantify socioeconomic inequalities based on childhood and adulthood socioeconomic position (SEP) in the risks and rates of multimorbidity accumulation across adulthood.Methods and findin
Externí odkaz:
https://doaj.org/article/025ea47d561d486fb875ccf88357bace
Publikováno v:
Results in Physics, Vol 26, Iss , Pp 104264- (2021)
In this paper, we propose a continuous-time stochastic intensity model, namely, two-phase dynamic contagion process (2P-DCP), for modelling the epidemic contagion of COVID-19 and investigating the lockdown effect based on the dynamic contagion model
Externí odkaz:
https://doaj.org/article/60d85658047d44a38ece9ffa34436271
Autor:
Judit García-González, Alistair J Brock, Matthew O Parker, Riva J Riley, David Joliffe, Ari Sudwarts, Muy-Teck Teh, Elisabeth M Busch-Nentwich, Derek L Stemple, Adrian R Martineau, Jaakko Kaprio, Teemu Palviainen, Valerie Kuan, Robert T Walton, Caroline H Brennan
Publikováno v:
eLife, Vol 9 (2020)
To facilitate smoking genetics research we determined whether a screen of mutagenized zebrafish for nicotine preference could predict loci affecting smoking behaviour. From 30 screened F3 sibling groups, where each was derived from an individual ethy
Externí odkaz:
https://doaj.org/article/5047a4e5ac344a06a8f71324faeda877
Autor:
Valerie Kuan, MBBS, Spiros Denaxas, PhD, Arturo Gonzalez-Izquierdo, PhD, Kenan Direk, PhD, Osman Bhatti, FRCGP, Shanaz Husain, MBBS, Shailen Sutaria, FFPH, Melanie Hingorani, FRCOphth, Dorothea Nitsch, ProfMD, Constantinos A Parisinos, MRCP, R Thomas Lumbers, PhD, Rohini Mathur, PhD, Reecha Sofat, PhD, Juan P Casas, ProfPhD, Ian C K Wong, ProfPhD, Harry Hemingway, ProfFFPH FRCP, Aroon D Hingorani, ProfPhD
Publikováno v:
The Lancet: Digital Health, Vol 1, Iss 2, Pp e63-e77 (2019)
Summary: Background: To effectively prevent, detect, and treat health conditions that affect people during their lifecourse, health-care professionals and researchers need to know which sections of the population are susceptible to which health condi
Externí odkaz:
https://doaj.org/article/e5b06d849205495190a8a2bda5d4673a
Autor:
Anoop D. Shah, Anuradhaa Subramanian, Jadene Lewis, Samir Dhalla, Elizabeth Ford, Shamil Haroon, Valerie Kuan, Krishnarajah Nirantharakumar
BACKGROUNDLong Covid is a widely recognised consequence of COVID-19 infection, but little is known about the burden of symptoms that patients present with in primary care, as these are typically recorded only in free text clinical notes. Our objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab18baedcf79492a3c85005e2118b5e8
https://doi.org/10.1101/2023.01.06.23284202
https://doi.org/10.1101/2023.01.06.23284202
Autor:
Valerie Kuan, Spiros Denaxas, Praveetha Patalay, Dorothea Nitsch, Rohini Mathur, Arturo Gonzalez-Izquierdo, Reecha Sofat, Linda Partridge, Amanda Roberts, Ian C K Wong, Melanie Hingorani, Nishi Chaturvedi, Harry Hemingway, Aroon D Hingorani, Daniel C Alexander, Innocent G Asiimwe, Simon Ball, Frances Bennett, Maria Carolina Borges, Adam Butterworth, Sandesh Chopade, Christopher Clarkson, Martin Cox, Caroline Dale, Diana Dunca, Jorgen E Engmann, Alba Fernandez-Sanles, Chris Finan, Natalie Fitzpatrick, Jean Gallagher, Jasmine Gratton, Christian Gross, Albert Henry, Mira Hidajat, Aroon Hingorani, Nikita Hukerikar, Andrea Jorgensen, Roshni Joshi, Michail Katsoulis, Rashmi Kumar, Alvina G Lai, Claudia Langenberg, Deborah Lawlor, Mary Mancini, Diane Miller, Margaret Ogden, Eda B Ozyigit, Shilpa Patel, Munir Pirmohamed, David Ryan, Amand F Schmidt, Anoop D Shah, Tina Shah, Rohan Takhar, Ana Torralbo, Ayath Ullah, Lauren E Walker, Alasdair Warwick, Eleanor Wheeler, Victoria L Wright, Honghan Wu, Magdalena Zwierzyna
Publikováno v:
Lancet Digit Health
BACKGROUND: Globally, there is a paucity of multimorbidity and comorbidity data, especially for minority ethnic groups and younger people. We estimated the frequency of common disease combinations and identified non-random disease associations for al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7846da2bd254f898cdef909442be297
https://hdl.handle.net/21.11116/0000-000B-B70D-9
https://hdl.handle.net/21.11116/0000-000B-B70D-9