Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Valerie Jenkins"'
Autor:
Sally Wheelwright, Lucy Matthews, Valerie Jenkins, Shirley May, Daniel Rea, Pat Fairbrother, Claire Gaunt, Jennie Young, Sarah Pirrie, Matthew G. Wallis, Lesley Fallowfield, on behalf of the LORIS Trial Management Group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background The LOw RISk DCIS (LORIS) study was set up to compare conventional surgical treatment with active monitoring in women with ductal carcinoma in situ (DCIS). Recruitment to trials with a surveillance arm is known to be challenging,
Externí odkaz:
https://doaj.org/article/503fbba1f83546d5b5e97ab96d86990c
Publikováno v:
Cancer Research. 83:OT1-13
Research question: Is it feasible to conduct a multicentre randomised controlled trial (RCT) to test the long-term efficacy and safety of biological matrices compared with synthetic meshes in women undergoing one-stage mesh and implant breast reconst
Autor:
Wei Tan, Alastair Thompson, Alan Montgomery, Sarah Craig, Laura Ternent, Eleanor Mitchell, Lelia Duley, Ian Ellis, Alistair Ring, Nicole Francis, Hannah Price, David Dodwell, Elizabeth Miles, Rebecca Haydock, Margaret Childs, Mara Ozolins, Diane Whitham, Apostolos Fakis, David Whynes, Patricia Fairbrother, Robert Newcombe, Malcolm Reed, Daniel Davis, Tara Homer, Kathryn Monson, Ramsey Cutress, Valerie Jenkins, Lesley Fallowfield, Clare Brittain, Daniel Rea, Judith Bliss, Amit Goyal, G Bruce Mann, Robert E Coleman, Shabina Sadiq, Heath Badger, Rachel Helen Haines, Mickey Lewis, Daniel Megias, Zohal Nabi, Preetinder Singh, Andrei Caraman, Romaana Mir, Teresa Grieve, Clare Upton, Aisha Shafayat, Charlotte Gidman, Flonda Probert, Lisa Paksec, Rose Lucas, Annette Dempsey, Rochelle Thornton, Roeum Butt, Peter Barrett Lee, Julie Wolfarth, Peter Dubsky
Publikováno v:
BMJ Open, Vol 11, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/12460454e606498ebdb4b066396a1d8f
Autor:
Lesley Fallowfield, Ivonne Solis-Trapala, Rachel Starkings, Shirley May, Lucy Matthews, Diana Eccles, D. Gareth Evans, Clare Turnbull, Gillian Crawford, Valerie Jenkins
Publikováno v:
Fallowfield, L, Solis-Trapala, I, Starkings, R, May, S, Matthews, L, Eccles, D, Evans, D G, Turnbull, C, Crawford, G & Jenkins, V 2022, ' Talking about Risk, UncertaintieS of Testing IN Genetics (TRUSTING) : development and evaluation of an educational programme for healthcare professionals about BRCA1 & BRCA2 testing ', BJC, vol. 127, no. 6, pp. 1116-1122 . https://doi.org/10.1038/s41416-022-01871-x
Background Mainstreaming of germline testing demands that all healthcare professionals have good communication skills, but few have genetic testing and counselling experience. We developed and evaluated educational workshops—Talking about Risk & Un
Autor:
Amit Goyal, Cydney Bruce, Shabina Sadiq, Mickey Lewis, Alan Montgomery, G Bruce Mann, Heath Badger, Kathryn Monson, Valerie Jenkins, Lesley Fallowfield, Malcolm Reed, David Dodwell, Patricia Fairbrother, Tara Homer, Luke Vale, Roeum Butt, Elizabeth Miles, Shelley Dowey, Lucy Matthews, Hugh Jarrett, Juliet Jackson, Arfan Ali
Publikováno v:
Cancer Research. 83:P5-01
Background: POSNOC is a UK-ANZ multicentre, non-inferiority, randomised trial comparing systemic therapy alone with systemic therapy plus Axillary Treatment (Axillary radiotherapy or ALND) for women with ≤2 macrometastases at SNB. The primary outco
Autor:
Lesley Fallowfield, Nina Fryer, Andrew Paramore, Valerie Jenkins, Shirley May, Amanda Ramirez
Publikováno v:
Cancer Research. 80:P2-14
Background Discussing risk of recurrence and potential treatment benefit in early breast cancer can be challenging, especially when dealing with anxious patients and/or those with difficult social circumstances. UK patients usually have access to spe
Publikováno v:
Cancer Research. 80:P2-12
The OPTION trial examined whether or not premenopausal women with early breast cancer receiving chemotherapy benefited from ovarian function protection with goserelin. This trial showed some preservation of ovarian function and fertility in women age
Autor:
Bethany Torr, Christopher Jones, Subin Choi, Sophie Allen, Grace Kavanaugh, Monica Hamill, Alice Garrett, Suzanne MacMahon, Lucy Loong, Alistair Reay, Lina Yuan, Mikel Valganon Petrizan, Kathryn Monson, Nicky Perry, Lesley Fallowfield, Valerie Jenkins, Rochelle Gold, Amy Taylor, Rhian Gabe, Jennifer Wiggins, Anneke Lucassen, Ranjit Manchanda, Ashu Gandhi, Angela George, Michael Hubank, Zoe Kemp, D Gareth Evans, Stephen Bremner, Clare Turnbull
Publikováno v:
Torr, B, Choi, S, Allen, S, Kavanaugh, G, Hamill, M, Garrett, A, MacMahon, S, Loong, L, Reay, A, Yuan, L, Valganon Petrizan, M, Monson, K, Perry, N, Fallowfield, L, Jenkins, V, Gold, R, Taylor, A, Gabe, R, Wiggins, J, Lucassen, A, Manchanda, R, Gandhi, A, George, A, Hubank, M, Kemp, Z, Evans, D G, Bremner, S & Turnbull, C 2022, ' A digital pathway for genetic testing in UK NHS patients with cancer : BRCA-DIRECT randomised study internal pilot ', Journal of Medical Genetics . https://doi.org/10.1136/jmg-2022-108655
BackgroundGermline genetic testing affords multiple opportunities for women with breast cancer, however, current UK NHS models for delivery of germline genetic testing are clinician-intensive and only a minority of breast cancer cases access testing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd56f4bf746f40812a6276eb8e07aa9
https://research.manchester.ac.uk/en/publications/280b7446-3bb8-46d5-a6bd-9809431c46fb
https://research.manchester.ac.uk/en/publications/280b7446-3bb8-46d5-a6bd-9809431c46fb
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Enterohemorrhagic and enteropathogenic Escherichia coli are gastrointestinal pathogens that disrupt the intestinal microvilli to form attaching and effacing (A/E) lesions on infected cells and cause diarrhea. This pathomorphological trait is encoded
Externí odkaz:
https://doaj.org/article/c584682067bb43bfacbf0c01e17b4616
Publikováno v:
Microorganisms, Vol 5, Iss 4, p 78 (2017)
The locus of enterocyte effacement is necessary for enteropathogenic Escherichia coli (EPEC) to form attaching and effacing (A/E) lesions. A/E lesions are characterized by intimate bacterial adherence to intestinal cells and destruction of microvilli
Externí odkaz:
https://doaj.org/article/31a9886acaec4acba51ffe2b03f8c975