Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valerie J. Carpenter"'
Autor:
Tareq Saleh, Valerie J. Carpenter, Liliya Tyutyunyk‐Massey, Graeme Murray, Joel D. Leverson, Andrew J. Souers, Moureq R. Alotaibi, Anthony C. Faber, Jason Reed, Hisashi Harada, David A. Gewirtz
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2504-2519 (2020)
Tumor cells undergo senescence in response to both conventional and targeted cancer therapies. The induction of senescence in response to cancer therapy can contribute to unfavorable patient outcomes, potentially including disease relapse. This possi
Externí odkaz:
https://doaj.org/article/b1ca93626c5148b4a9daf8f17d95e358
Autor:
Tareq Saleh, Valerie J. Carpenter
Publikováno v:
Molecular Pharmacology. 100:580-587
Senescence is a cell state that contributes to several homeostatic and pathologic processes. In addition to being induced in somatic cells in response to replicative exhaustion (replicative senescence) as part of organismal aging, senescence can also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7620f71a40b71ba153040a25db05f11a
https://doi.org/10.1124/molpharm.121.000361
https://doi.org/10.1124/molpharm.121.000361
Autor:
Liliya Tyutyunyk-Massey, Tareq Saleh, Jason Reed, Valerie J. Carpenter, Andrew J. Souers, Anthony C. Faber, Joel D. Leverson, Graeme F. Murray, Hisashi Harada, David A. Gewirtz, Moureq R. Alotaibi
Publikováno v:
Molecular Oncology, Vol 14, Iss 10, Pp 2504-2519 (2020)
Tumor cells undergo senescence in response to both conventional and targeted cancer therapies. The induction of senescence in response to cancer therapy can contribute to unfavorable patient outcomes, potentially including disease relapse. This possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f33bad01b1dda0210c0351badfb89fc6
https://doi.org/10.1002/1878-0261.12761
https://doi.org/10.1002/1878-0261.12761
Publikováno v:
Minerva urology and nephrology. 73(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8580a2fd46fa11842d40fcd8951620
https://pubmed.ncbi.nlm.nih.gov/34114789
https://pubmed.ncbi.nlm.nih.gov/34114789
Autor:
Valerie J. Carpenter, David A. Gewirtz, Tareq Saleh, Andrew J. Souers, Jason Reed, So Min Lee, Graeme F. Murray, Hisashi Harada, Anthony C. Faber
Publikováno v:
Biochemical pharmacology. 193
Prostate cancer (PCa) is one of the leading causes of cancer-related deaths in men. Although androgen deprivation therapies (ADT) and antiandrogens confer increased survival rates, most patients eventually develop castration resistant disease (CRPC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522734acdc3980ceeb5524c1b72a6f89
https://pubmed.ncbi.nlm.nih.gov/34536356
https://pubmed.ncbi.nlm.nih.gov/34536356
Autor:
Ahmad T. Mansour, Tareq Saleh, Bilal Azab, Mohammed El-Sadoni, Omar Abuelaish, Valerie J. Carpenter, Mahmoud Al-Balas, Ahmad Alhesa, Heyam Awad
Publikováno v:
Bioscience Reports
Senescence is a cell stress response induced by replicative, oxidative, oncogenic, and genotoxic stresses. Tumor cells undergo senescence in response to several cancer therapeutics in vitro (Therapy-Induced Senescence, TIS), including agents utilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bffa0f310fdbdd3a3ced06fb3ab78e9
http://europepmc.org/articles/PMC8725197
http://europepmc.org/articles/PMC8725197
Autor:
Virginia D. McLane, Viktor Yarotskyy, Sara R. Nass, Pamela E. Knapp, Jingli Zhang, Aaron J. Barbour, A. Rory McQuiston, Kurt F. Hauser, Jean Moon, William D. Marks, Jason J. Paris, Arianna R.S. Lark, Valerie J. Carpenter
Publikováno v:
eNeuro
About half the people infected with HIV have neurocognitive deficits that often include memory impairment and hippocampal deficits, which can be exacerbated by opioid abuse. To explore the effects of opioids and HIV on hippocampal CA1 pyramidal neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb67ef218c0865d433d979b191cb3eb
http://europepmc.org/articles/PMC8146490
http://europepmc.org/articles/PMC8146490
Publikováno v:
Semin Cancer Biol
Senescence is a unique state of growth arrest that develops in response to a plethora of cellular stresses, including replicative exhaustion, oxidative injury, and genotoxic insults. Senescence has been implicated in the pathogenesis of multiple agin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640872e5ffcc1fc45e1bbb4d1a110e5e
https://pubmed.ncbi.nlm.nih.gov/33358748
https://pubmed.ncbi.nlm.nih.gov/33358748
Autor:
Steven C. Smith, David A. Gewirtz, Tareq Saleh, Valerie J. Carpenter, Riccardo Autorino, Bhaumik B. Patel
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1874(2)
The development of Castration-Resistant Prostate Cancer (CRPC) remains a major challenge in the treatment of this disease. While Androgen Deprivation Therapy (ADT) can result in tumor shrinkage, a primary response of Prostate Cancer (PCa) cells to AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd97dd4f8ada3bb5b343c72147f2b57b
https://pubmed.ncbi.nlm.nih.gov/32956765
https://pubmed.ncbi.nlm.nih.gov/32956765
Autor:
Sarah Bloukh, Jomana Bakeer, Valerie J. Carpenter, Sarah Darwish, Belal Azab, David A. Gewirtz, Enas Alwohoush, Tareq Saleh
Publikováno v:
Cancers
Cancers, Vol 12, Iss 822, p 822 (2020)
Cancers, Vol 12, Iss 822, p 822 (2020)
For the past two decades, cellular senescence has been recognized as a central component of the tumor cell response to chemotherapy and radiation. Traditionally, this form of senescence, termed Therapy-Induced Senescence (TIS), was linked to extensiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5475326b6b8751558c3f3358b5b8e82a
https://pubmed.ncbi.nlm.nih.gov/32235364
https://pubmed.ncbi.nlm.nih.gov/32235364