Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Valerie Huynh"'
Autor:
Thiago M. A. Santos, Katherine A. Hurley, Valerie Huynh, Jared T. Shaw, Douglas B. Weibel, Gabriella M. Nepomuceno
Publikováno v:
Journal of Medicinal Chemistry. 59:6975-6998
Similar to its eukaryotic counterpart, the prokaryotic cytoskeleton is essential for the structural and mechanical properties of bacterial cells. The essential protein FtsZ is a central player in the cytoskeletal family, forms a cytokinetic ring at m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5970cda476685767612e1d9ce5d3938
https://doi.org/10.1021/acs.jmedchem.5b01098
https://doi.org/10.1021/acs.jmedchem.5b01098
Publikováno v:
The Journal of organic chemistry, vol 81, iss 22
A short, diastereoselective synthesis of homocitric acid lactone is described. The key step is a bioinspired aldol addition to set the stereogenic center in an intermediate that requires only modest oxidation state manipulation to complete the synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65287ad4027d64aea4e3c587edbc64e0
https://pubmed.ncbi.nlm.nih.gov/27685496
https://pubmed.ncbi.nlm.nih.gov/27685496
Autor:
Jared T. Moore, Valerie Huynh, Kevin S. Martin, Terrence E. O’Brien, Zi Yao, David E. Anderson, James B. Ames, Clarissa Tadeus, Luiz A. E. Pollo, Gabriella M. Nepomuceno, Katie M. Chan, Jared T. Shaw, Francisco J. Sarabia
Publikováno v:
Nepomuceno, GM; Chan, KM; Huynh, V; Martin, KS; Moore, JT; Obrien, TE; et al.(2015). Synthesis and evaluation of quinazolines as inhibitors of the bacterial cell division protein FtsZ. ACS Medicinal Chemistry Letters, 6(3), 308-312. doi: 10.1021/ml500497s. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/6098r49t
ACS medicinal chemistry letters, vol 6, iss 3
ACS medicinal chemistry letters, vol 6, iss 3
© 2015 American Chemical Society. The bacterial cell division protein FtsZ is one of many potential targets for the development of novel antibiotics. Recently, zantrin Z3 was shown to be a cross-species inhibitor of FtsZ; however, its specific inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b7f6c96d5df05f51f3161cfc88afd1
http://www.escholarship.org/uc/item/6098r49t
http://www.escholarship.org/uc/item/6098r49t
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 29, Iss 2, Pp 91-94 (2015)
BACKGROUND: Clinical experiences of adults who underwent surgery for esophageal atresia at birth is limited. There is some evidence that suggests considerable long-term morbidity, partly because of dysphagia, which has been reported in up to 85% of a
Externí odkaz:
https://doaj.org/article/0825fd6ee9e44623a3dc45dc7b300f47