Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valerie Hindie"'
Autor:
TomoKazu Tsurugizawa, Damien Marechal, Aude-Marie Lepagnol-Bestel, Jean-Christophe Rain, Michel Simonneau, Martina Reiss, Nicolas Bourg, Helin Atas-Ozcan, Alexandra Winkeler, Valerie Hindie, Jocelyn Laporte, Patrick Dutar, Jorge Diaz, Doulaye Dembélé, Guillaume Dupuis, Yoshifumi Abe, Harald Kranz, Maxime Sartori, Denis Le Bihan, Claire Chevalier, Chiara Guerrera, Guillaume Pavlovic, Bernard Malissen, Roxane Golgolab, Luisa Ciobanu, Andrew M. McKenzie, Sandrine Lévêque-Fort, Brigitte Potier, Bin Zhang, Loic Lindner, Joanna Lipecka, Christelle Thibault-Carpentier, Julia Viard, Elisabeth Davenas, Cyril Poupon, Yann Herault, Ivy Uszynski, Marie-Christine Birling, Qing Jun Wang, Rachel Daudin, Yann Loe-Mie
Publikováno v:
SSRN Electronic Journal.
Genetic factors are known to contribute to Late Onset Alzheimer’s disease (LOAD) but their contribution to pathophysiology, specially to prodomic phases accessible to therapeutic approaches are far to be understood. To translate genetic risk of Alz
Autor:
Julia Viard, Guofa Liu, Jean Christophe Rain, Henri Bléhaut, Thomas Moncion, Malik Khelfaoui, Rachel Daudin, Clotilde Mircher, Yann Herault, Eunjoon Kim, Richard L. Huganir, Francisco J. Tejedor, Eugene Yu, Makoto Kinoshita, Christine Plancon, Yann Loe-Mie, Michel Simonneau, Aude-Marie Lepagnol-Bestel, Jean-François Deleuze, Anne Boland, Volker Haucke, Valerie Hindie
Intellectual disability (ID) found in Down syndrome (DS), which is characterized by an extra copy of 234 genes on Chr21 is poorly understood. We first used two DS mouse models that either display an extra copy of the Dyrk1A gene or of the mouse Chr16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eef638bef824b32b05377fed456cd96
https://hal.archives-ouvertes.fr/hal-03065473
https://hal.archives-ouvertes.fr/hal-03065473
Autor:
Elena Sügis, Rachel Daudin, Vincent Collura, Yann Herault, Valerie Hindie, Yann Loe-Mie, Jean-Charles Lambert, Michel Simonneau, Jérôme Dauvillier, Priit Adler, Hedi Peterson, Thomas Moncion, Henning Hermjakob, Anna Leontjeva, Jean-Christophe Rain, Tal Pupko, Jaak Vilo, Ioannis Xenarios
Publikováno v:
Scientific Data
Scientific Data, Nature Publishing Group, 2019, 6 (1), pp.151. ⟨10.1038/s41597-019-0152-0⟩
Scientific data, vol. 6, no. 1, pp. 151
Scientific Data, 2019, 6 (1), pp.151. ⟨10.1038/s41597-019-0152-0⟩
Scientific Data, Vol 6, Iss 1, Pp 1-18 (2019)
Scientific Data, Nature Publishing Group, 2019, 6 (1), pp.151. ⟨10.1038/s41597-019-0152-0⟩
Scientific data, vol. 6, no. 1, pp. 151
Scientific Data, 2019, 6 (1), pp.151. ⟨10.1038/s41597-019-0152-0⟩
Scientific Data, Vol 6, Iss 1, Pp 1-18 (2019)
Alzheimer’s disease and other types of dementia are the top cause for disabilities in later life and various types of experiments have been performed to understand the underlying mechanisms of the disease with the aim of coming up with potential dr
Autor:
Michel Mallat, Fabrice Daubigney, Catherine Colin, Sandrine Middendorp, Jean-Christophe Rain, Nadim Kassis, Valerie Hindie, M.L. Arbonés, Blandine Gausserès, Jean-Maurice Delabar, Jean-Louis Paul, Nathalie Janel, Yuchen Gu, Eugene Yu, Alizée Latour
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2019, 56 (2), pp.963-975. ⟨10.1007/s12035-018-1113-x⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurobiology, Humana Press, 2019, 56 (2), pp.963-975. ⟨10.1007/s12035-018-1113-x⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
International audience; Down syndrome is characterized by premature aging and dementia with neurological features that mimic those found in Alzheimer's disease. This pathology in Down syndrome could be related to inflammation, which plays a role in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1f26769338a1ae350f08e7f4bdceea
https://hal-cnrs.archives-ouvertes.fr/hal-03201563
https://hal-cnrs.archives-ouvertes.fr/hal-03201563
Autor:
Marie-Christine Birling, Y Abe, Jean-Christophe Rain, Martina Reiss, Maxime Sartori, I. Uszynski, Christelle Thibault-Carpentier, Alexandra Winkeler, Julia Viard, Andrew M. McKenzie, D Le Bihan, Bernard Malissen, Harald Kranz, Damien Marechal, Guillaume Dupuis, Cyril Poupon, Aude-Marie Lepagnol-Bestel, R Golgolab, Yann Loe-Mie, Chiara Guerrera, Helin Atas-Ozcan, B Potier, Valerie Hindie, Jocelyn Laporte, Luisa Ciobanu, Jorge Diaz, Guillaume Pavlovic, R Daudin, Yann Herault, Loic Lindner, Joanna Lipecka, Tomokazu Tsurugizawa, Sandrine Lévêque-Fort, Qing Jun Wang, Elisabeth Davenas, Doulaye Dembélé, Claire Chevalier, P. Dutar, Michel Simonneau, Bin Zhang, Nathalie Bourg
Late Onset Alzheimer Disease (LOAD) is the most common form of dementia and one of the most challenging diseases of modern society. Understanding the preclinical stages of AD that begins in the brain at least 2 to 3 decades before evidence of episodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7730c59a0190bf3be5e31ebeae482b9
https://doi.org/10.1101/437228
https://doi.org/10.1101/437228
Autor:
P. Dutar, Michel Simonneau, Yann Loe-Mie, Nathalie Bourg, S. Leveque Fort, Guillaume Dupuis, Brigitte Potier, Jean-Christophe Rain, Julia Viard, Marie-Christine Birling, Yann Herault, Aude-Marie Lepagnol-Bestel, Guillaume Pavlovic, Valerie Hindie, Jocelyn Laporte, Maxime Sartori, Rachel Daudin, Damien Marechal
Publikováno v:
European Neuropsychopharmacology. 27:S742-S743
Autor:
Ricardo M. Biondi, Valerie Hindie, Rolf W. Hartmann, L.A. Lopez-Garcia, Matthias Engel, Wolfgang Fröhner, Francis Schaeffer, Iris Adrian, Adriana Stroba
Publikováno v:
Journal of Medicinal Chemistry. 52:4683-4693
The modulation of protein kinase activities by low molecular weight compounds is a major goal of current pharmaceutical developments. In this line, important efforts are directed to the development of drugs targeting the conserved ATP binding site. H
Autor:
Pinar Coskun, Fabian Corlier, Marie Sarazin, Foudil Lamari, Jean Maurice Delabar, Valerie Hindie, Hélène Corne, Jean Christophe Rain, M.L. Arbonés, Leonardo Cruz de Souza, Marie-Claude Potier, Ira T. Lott, Jean-Louis Paul, Jorge Busciglio, Michel Bottlaender, Nathalie Janel, Henri Bléhaut
Publikováno v:
Alzheimer's & Dementia. 10
Publikováno v:
The FASEB Journal. 25
Autor:
Fabian Corlier, L. C. de Souza, Bruno Dubois, Nathalie Janel, Julien Lagarde, J-C Rain, Jean M. Delabar, H Corne, Valerie Hindie, M.L. Arbonés, Michel Bottlaender, Marie-Claude Potier, Lorraine Hamelin, Henri Bléhaut, Marie Sarazin, A Aka
Publikováno v:
Translational Psychiatry
Translational Psychiatry, 2014, 4, pp.e425. ⟨10.1038/tp.2014.61⟩
Translational Psychiatry, Nature Pub. Group, 2014, 4, pp.e425. ⟨10.1038/tp.2014.61⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Translational Psychiatry, 2014, 4, pp.e425. 〈10.1038/tp.2014.61〉
Translational Psychiatry, 2014, 4, pp.e425. ⟨10.1038/tp.2014.61⟩
Translational Psychiatry, Nature Pub. Group, 2014, 4, pp.e425. ⟨10.1038/tp.2014.61⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Translational Psychiatry, 2014, 4, pp.e425. 〈10.1038/tp.2014.61〉
To determine whether apparent involvement of DYRK1A in Alzheimer's disease (AD) pathology makes it a candidate plasma biomarker for diagnosis, we developed a method to quantify plasma DYRK1A by immunoblot in transgenic mouse models having different g