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pro vyhledávání: '"Valerie Granados"'
Autor:
Rehana Z. Hussain, Todd N. Eagar, Richard Doelger, Valerie Granados, William A. Miller-Little, Olaf Stüve, Petra D. Cravens, Darin T. Okuda, Emily Herndon
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
ObjectiveThe goal of this study was to investigate the role of CD 19+B cells within the brain and spinal cord during CNS autoimmunity in a peptide-induced, primarily T-cell–mediated experimental autoimmune encephalomyelitis (EAE) model of MS. We hy
Publikováno v:
The Journal of Immunology. 186:147.9-147.9
In the U.S., over two-thirds of adults are overweight or obese, which correlates with chronic inflammation and is marked by an inability to effectively clear infection. Leptin, a pleiotropic adipokine, directly affects immunity via actions on immune
Publikováno v:
The Journal of Immunology. 184:130.7-130.7
Leptin is a pleiotropic cytokine/hormone that has been shown to play a critical role in immunity, including dendritic cells (DC). In vitro experiments in mice and humans have shown that short term leptin treatment results in enhanced DC function. We