Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valerie Girling"'
Autor:
Steven A Yukl, Amandeep K Shergill, Valerie Girling, Qingsheng Li, Maudi Killian, Lorrie Epling, Peilin Li, Philipp Kaiser, Ashley Haase, Diane V Havlir, Kenneth McQuaid, Elizabeth Sinclair, Joseph K Wong
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121290 (2015)
Gastrointestinal T lymphocytes are critical for mucosal immunity and HIV pathogenesis, yet little is known about normal T cell numbers and phenotypes in different regions of the gut, or the degree to which ART can restore levels to those of HIV-uninf
Externí odkaz:
https://doaj.org/article/7a8df5c21ac1472ead6f187884857ba2
Autor:
Jonathan Karn, Rowena Johnston, Rebecca Hoh, Robert J. Gorelick, Peter Bacchetti, Ajantha Solomon, Marcelle I. Cedars, Eileen P. Scully, Monica Gandhi, Arlvin Ellefson, Steven G. Deeks, Amélie Pagliuzza, Ainsley Lockhart, Nicolas Chomont, Marcus Altfeld, Jeffrey M. Milush, Curtis Dobrowolski, Jeffrey D. Lifson, Christopher A Baker, Galit Alter, Sharon R Lewin, Valerie Girling
Publikováno v:
The Journal of infectious diseases, vol 219, iss 7
Plasma human immunodeficiency virus type 1 (HIV-1) RNA levels in women are lower early in untreated HIV-1 infection compared with those in men, but women have higher T-cell activation and faster disease progression when adjusted for viral load. It is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ed9adc064f0a724c9b88d8890260af
https://pubmed.ncbi.nlm.nih.gov/30371873
https://pubmed.ncbi.nlm.nih.gov/30371873
Autor:
Mark Pandori, Steven A. Yukl, Lorrie Epling, Katsuya Fujimoto, Peilin Li, Terence Ho, Amandeep K. Shergill, Alex Choi, Marek Fischer, Harry Lampiris, Joseph K. Wong, Sara Gianella, Huldrych F. Günthard, Lijie Duan, C. Bradley Hare, Kenneth R. McQuaid, Diane V. Havlir, Valerie Girling, Elizabeth Sinclair, Ashley T. Haase, Qingsheng Li
Publikováno v:
The Journal of infectious diseases
Background. The gut is a major reservoir for human immunodeficiency virus (HIV) in patients receiving antiretroviral therapy (ART). We hypothesized that distinct immune environments within the gut may support varying levels of HIV.Methods. In 8 HIV-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7eacf333e068fb06e092bd44e24a4b
http://doc.rero.ch/record/301653/files/202-10-1553.pdf
http://doc.rero.ch/record/301653/files/202-10-1553.pdf
Autor:
Nicolas Chomont, Rémi Fromentin, Ajantha Solomon, Peter W. Hunt, Wendy Hartogensis, Ma Somsouk, Rebecca Hoh, Steven G. Deeks, Marisela Killian, Sharon R Lewin, Paul U. Cameron, Frederick Hecht, Gabriela Khoury, Valerie Girling, Elizabeth Sinclair, Peter Bacchetti, Jenny L. Anderson
Background: Immune activation and inflammation remain elevated in human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART) and may contribute to HIV persistence. Methods: Using flow cytometry expression of CD38,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692fd2e43956333e3d86e8ebf4065d28
https://europepmc.org/articles/PMC5407052/
https://europepmc.org/articles/PMC5407052/
Autor:
Elizabeth Sinclair, Diane V. Havlir, Steven A. Yukl, Peilin Li, Lisa K. Wong, Lorrie Epling, Pierre Crouch, Valerie Girling, Joseph K. Wong, Terence Ho, Kenneth R. McQuaid, Amandeep K. Shergill, Maudi Killian, Steven G. Deeks
Publikováno v:
The Journal of infectious diseases, vol 208, iss 8
Even with optimal antiretroviral therapy, human immunodeficiency virus (HIV) persists in plasma, blood cells, and tissues. To develop new therapies, it is essential to know what cell types harbor residual HIV. We measured levels of HIV DNA, RNA, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0d034590c7becd4219f1dcab4a0788
https://doi.org/10.1093/infdis/jit308
https://doi.org/10.1093/infdis/jit308
Autor:
Chungkee Poon, Qi Xuan Tan, Douglas A. Jabs, Mark L. Van Natta, Valerie Girling, Margaret Inokuma, Mark A. Jacobson, Barry M. Bredt, Holden T. Maecker, Elizabeth Sinclair
Publikováno v:
Clinical Infectious Diseases. 46:458-466
Background. We examined the potential clinical utility of using a cytomegalovirus (CMV)–specific T cell immunoassay to determine the risk of developing new-onset CMV retinitis (CMVR) in patients with acquired immunodeficiency syndrome (AIDS). Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358e5be8d256b56997310dcadc4b35bd
https://doi.org/10.1086/525853
https://doi.org/10.1086/525853
Autor:
Peilin Li, Ashley T. Haase, Steven A. Yukl, Joseph K. Wong, Valerie Girling, Elizabeth Sinclair, Diane V. Havlir, Amandeep K. Shergill, Lorrie Epling, Maudi Killian, Qingsheng Li, Philipp Kaiser, Kenneth R. McQuaid
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121290 (2015)
Wong, Joseph; Havlir, Diane; McQuaid, Kenneth; Yukl, SA; Shergill, AK; Girling, V; et al.(2015). Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/4qd2655x
PLoS ONE
Wong, Joseph; Havlir, Diane; McQuaid, Kenneth; Yukl, SA; Shergill, AK; Girling, V; et al.(2015). Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/4qd2655x
PLoS ONE
Gastrointestinal T lymphocytes are critical for mucosal immunity and HIV pathogenesis, yet little is known about normal T cell numbers and phenotypes in different regions of the gut, or the degree to which ART can restore levels to those of HIV-uninf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b6714f5b1c7144cb7b7077632a63a5
http://europepmc.org/articles/PMC4374729?pdf=render
http://europepmc.org/articles/PMC4374729?pdf=render
Autor:
Douglas A. Jabs, Margaret Inokuma, Margaret Sharp, Chungkee Poon, Qi Xuan Tan, Elizabeth Sinclair, Mark L. Van Natta, Holden T. Maecker, Valerie Girling, Barry M. Bredt
Publikováno v:
The Journal of Infectious Diseases. 194:1537-1546
To determine potential correlates of immune recovery from AIDS-related cytomegalovirus retinitis (CMVR), multiparameter flow cytometry was used to characterize CMV-specific T cells from subjects with CMVR. Individuals with active retinitis were compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ca18a73370c3adf358c48104d8f6a7
https://doi.org/10.1086/508997
https://doi.org/10.1086/508997
Autor:
Diane V. Havlir, Peilin Li, Ma Somsouk, Steven A. Yukl, Joseph K. Wong, Steven G. Deeks, Peter W. Hunt, Lorrie Epling, Valerie Girling, Maudi Killian, Elizabeth Sinclair, Hiroyu Hatano
Publikováno v:
AIDS (London, England), vol 28, iss 3
We compared different techniques for measuring gut HIV reservoirs and assessed for HIV in non-CD4+T cells. HIV DNA levels were similar when measured from rectal biopsies and isolated rectal cells, while HIV RNA tended to be higher in rectal cells. HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfea907a6f3ab82469e165a47e8a057
https://europepmc.org/articles/PMC4130176/
https://europepmc.org/articles/PMC4130176/
Autor:
Laurie Agrillo, Barry M. Bredt, Mark A. Jacobson, Stuart P. Adler, Terence Ho, Elizabeth Sinclair, C. Lorrie Epling, Douglas Black, Raji Bains, Valerie Girling, Alexander Carvidi
Publikováno v:
Vaccine. 24(25)
The Towne, human cytomegalovirus (CMV) vaccine is safe and immunogenic but has not prevented infection at doses tested to date. We administered 3000 pfu Towne CMV vaccine, with or without adjuvant recombinant interleukin-12 (rhIL-12), to CMV-seronega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68e1e830eb4a391d2b5bdf0868723d2
https://pubmed.ncbi.nlm.nih.gov/16701925
https://pubmed.ncbi.nlm.nih.gov/16701925