Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Valerie Fremont"'
Autor:
Bruce D. Weintraub, Torsten Kuwert, Martin G. Pomper, Valerie Fremont, Mariusz W. Szkudlinski, Simone Maschauer, Vladimir Wolf, Catherine A. Foss, Sridhar Nimmagadda, Olaf Prante, Julia Reinfelder
Publikováno v:
Thyroid. 21:783-792
Superagonist analogs of human thyroid-stimulating hormone (hTSH) may stimulate the uptake of (131)I-iodide and (18)F-fluorodeoxyglucose ((18)F-FDG) in thyroid carcinomas to a greater degree than hTSH. We herein report the potency and efficacy of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe15d41a7d040381a1df3b5e241de498
https://doi.org/10.1089/thy.2010.0394
https://doi.org/10.1089/thy.2010.0394
Autor:
Julia Reinfelder, Robert Stoehr, Valerie Fremont, Simone Maschauer, Mariusz W. Szkudlinski, Olaf Prante, Bruce D. Weintraub, Arndt Hartmann, Torsten Kuwert
Publikováno v:
Journal of Nuclear Medicine. 50:1364-1370
Dedifferentiation of thyroid carcinoma is accompanied by increased accumulation of the PET tracer (18)F-FDG. The molecular mechanisms responsible for this phenomenon are poorly understood. Therefore, we studied the regulation of (18)F-FDG uptake by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7f0b8ea26ff8fa15b3c1c5b5adce6d
https://doi.org/10.2967/jnumed.109.062331
https://doi.org/10.2967/jnumed.109.062331
Autor:
Krassimira Angelova, Mariusz W. Szkudlinski, Valerie Fremont, David Puett, Meng Zhang, Renita Jain, Prema Narayan
Publikováno v:
Endocrine. 24:025-032
The alpha-subunit is common to the heterodimeric glycoprotein hormones and has been highly conserved throughout vertebrate evolution. In an effort to determine if wild-type and engineered human alpha analogs can serve as agonists or antagonists to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35bb0a2b6b6212ac0b4b0399e5fae26
https://doi.org/10.1385/endo:24:1:025
https://doi.org/10.1385/endo:24:1:025
Autor:
Bruce D. Weintraub, Alberto Signore, Filippo Galli, Valerie Fremont, Mariusz W. Szkudlinski, Lajos Balogh, Giulia Piaggio, Rudi Dierckx, Isabella Manni
Publikováno v:
Thyroid, 24(8), 1297-1308. MARY ANN LIEBERT, INC
Background: Differentiated thyroid carcinomas originating from thyroid follicular cells are frequent tumors of the thyroid with relatively good prognosis due to improved surgical techniques and follow-up procedures. Poorly differentiated thyroid canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f12ceaddcedc3b8e568b128941e795
http://hdl.handle.net/11573/652057
http://hdl.handle.net/11573/652057
Autor:
Theodore J. Mullmann, Gilles Ferrat, Kathleen M. Giangiacomo, Herve Darbon, Valerie Fremont, Cedric Bernard
Publikováno v:
Biochemistry. 40:10998-11006
Noxiustoxin (NxTX) and iberiotoxin (IbTX) exhibit extraordinary differences in their ability to inhibit current through the large-conductance calcium-activated potassium (maxi-K) and voltage-gated potassium (Kv1.3) channels. The three-dimensional str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eff0ce5619118061bdb483e338a8a2b
https://doi.org/10.1021/bi010228e
https://doi.org/10.1021/bi010228e
Autor:
Bruce D. Weintraub, David Puett, Perma Narayan, Kim Phuong T. Tong, Valerie Fremont, Judy Chen, Meng Zhang, Mariusz W. Szkudlinski
Publikováno v:
Endocrinology. 141:3514-3517
Among glycoprotein hormone receptors the TSH receptor (TSHR) is the most susceptible to constitutive activation by mutations in various regions of the molecule, including mutations in the extracellular domain (ECD) and extracellular loops of the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da7365c704c24e4f9d46c49f825c1ae
https://doi.org/10.1210/endo.141.9.7790
https://doi.org/10.1210/endo.141.9.7790
Autor:
Theodore J. Mullmann, Kathleen M. Giangiacomo, Robert H. Cox, Maria L. Garcia, Valerie Fremont, Markus Hanner
Publikováno v:
Biochemistry. 39:6115-6122
The maxi-K channel from bovine aortic smooth muscle consists of a pore-forming alpha subunit and a regulatory beta1 subunit that modifies the biophysical and pharmacological properties of the alpha subunit. In the present study, we examine ChTX-S10A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceca60f141855f9e8d66a632d86e7d3
https://doi.org/10.1021/bi992865z
https://doi.org/10.1021/bi992865z
Publikováno v:
Perspectives in Drug Discovery and Design. :167-186
This review examines recent work aimed at revealing the molecular structures of the potassium channel vestibules using the α-K toxin (α-KTx) peptide blockers from the venoms of scorpions. The three subfamilies of α-K toxins are discussed in terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0a589cea98349d793cc05cc4c4634e
https://doi.org/10.1023/a:1017020325315
https://doi.org/10.1023/a:1017020325315
Publikováno v:
Physiological reviews. 82(2)
This review focuses on recent advances in the structure-function relationships of thyroid-stimulating hormone (TSH) and its receptor. TSH is a member of the glycoprotein hormone family constituting a subset of the cystine-knot growth factor superfami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3448b033c0d46743a0504ca95b5d321b
https://pubmed.ncbi.nlm.nih.gov/11917095
https://pubmed.ncbi.nlm.nih.gov/11917095