Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Valerie Fliakas-Boltz"'
Autor:
Joseph L. Roberson, William Decker, Sherman F. Stinson, Melinda G. Hollingshead, John P. Bader, Luke A. Pallansch, Carrie Bonomi, Tim Siford, Robert Shores, Suzanne Borgel, Louis Malspeis, Robert W. Buckheit, Valerie Fliakas-Boltz, Cindy Elder
Publikováno v:
AIDS Research and Human Retroviruses. 13:789-796
A series of compounds related to oxathiin carboxanilide has been identified as nonnucleoside reverse transcriptase inhibitors (NNRTIs) of HIV-1, and structure-activity relationships have been described (Buckheit RW, et al.: Antimicrob Agents Chemothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae15a786ec40097caf66f6b99b36134
https://doi.org/10.1089/aid.1997.13.789
https://doi.org/10.1089/aid.1997.13.789
Autor:
Valerie Fliakas-Boltz, Julie Russell, M J Snow, Luke A. Pallansch, W G Brouwer, T L Kinjerski, S. S. Yang, Robert W. Buckheit
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:831-837
The structure-activity relationships of a series of compounds related to the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) oxathiin carboxanilide have been described (R. W. Buckheit, Jr., T. L. Kinjerski, V. Fliakas-Boltz, J. D. Russell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37261729c318a8231d261d8e6b887165
https://doi.org/10.1128/aac.41.4.831
https://doi.org/10.1128/aac.41.4.831
Autor:
Valerie Fliakas-Boltz, Murray Zanger, T. N. Khan, M J Snow, Julie Russell, Luke A. Pallansch, S. S. Yang, J. P. Bader, Robert W. Buckheit
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:243-252
Structure-activity relationship evaluations with a series of diarylsulphone non-nucleoside reverse transcriptase (RT) inhibitors indicated that the steric properties of the molecule and compound lipophilicity primarily contributed to the overall leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39ee295557f98adace956f367ac5bb4f
https://doi.org/10.1177/095632029600700504
https://doi.org/10.1177/095632029600700504
Autor:
John P. Bader, Sharon Yeagy-Bargo, Shih-Hsi Chu, Bai-Chuan Pan, Owen S. Weislow, Robert W. Buckheit, Douglas L. Mayers, Stephen H. Hughes, Paul L. Boyer, Valerie Fliakas-Boltz
Publikováno v:
Virology. 210:186-193
Virus isolates resistant to 1-[(2-hydroxyethoxy) methyl]-6-(phenylthio)thymine (HEPT) and a highly potent HEPT derivative, [1-benzyloxymethyl-5-ethyl-6-(α-pyridylthio)uracil] (NSC 648400, E-BPTU), were selected in cell culture. Cross-resistance eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f212453de8e5ae1d989050d76b467d03
https://doi.org/10.1006/viro.1995.1330
https://doi.org/10.1006/viro.1995.1330
Autor:
Valerie Fliakas-Boltz, Michael R. Boyd, Michael J. Currens, Tracy L. Stup, Joseph L. Roberson, William Decker, C A Pyle, E L White, James B. McMahon, Robert W. Buckheit
Publikováno v:
Antiviral Research. 26:117-132
We have biologically and biochemically evaluated a structurally diverse group of HIV-1-specific reverse transcriptase (RT) inhibitors and determined that the members of this class share many common properties. These include reproducible and selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb56f747810d46cabb7378f11f61284
https://doi.org/10.1016/0166-3542(94)00069-k
https://doi.org/10.1016/0166-3542(94)00069-k
Autor:
John P. Bader, E. Lucile White, Bonnie J. Bowdon, Joseph L. Roberson, W. Don Decker, James B. McMahon, Tammy Antonucci, Valerie Fliakas-Boltz, Cathi A. Pyle, Hubert Barth, Michael R. Boyd, Robert W. Buckheit, David G. Nickell
Publikováno v:
Antiviral Research. 25:43-56
A series of benzothiadiazine derivatives were screened against the human immunodeficiency virus (HIV) and certain structure-activity relationships were defined for anti-HIV activity in this chemical class. The selected representative NSC 287474 was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c776a765c4fa882b09cf56eac5ea88
https://doi.org/10.1016/0166-3542(94)90092-2
https://doi.org/10.1016/0166-3542(94)90092-2
Autor:
Tracy L Loftus, Jong-Sun Lee, Karen M. Watson, Mark C. Osterling, Shu-An Lee, Eui Hwan Cho, Luke A. Pallansch, Valerie Fliakas-Boltz, J.-W. Oh, Julie Russell, Ho Seok Kwon, Jim A. Turpin, Chung Sun-Gan, Robert W. Buckheit, E. Lucile White
Publikováno v:
Antimicrobial agents and chemotherapy. 45(2)
We have identified and characterized a potent new nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) that also is active against HIV-2 and which interferes with virus replication by two distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0885fdf8367db989aeb38afa6630a28d
https://pubmed.ncbi.nlm.nih.gov/11158731
https://pubmed.ncbi.nlm.nih.gov/11158731
Autor:
T L Kinjerski, E. Lucile White, Tracy L. Stup, Julie Russell, Ann Weigand, Valerie Fliakas-Boltz, Mark C. Osterling, Robert W. Buckheit, John P. Bader
(+)-Calanolide A (NSC 650886) has previously been reported to be a unique and specific nonnucleoside inhibitor of the reverse transcriptase (RT) of human immunodeficiency virus (HIV) type 1 (HIV-1) (M. J. Currens et al., J. Pharmacol. Exp. Ther., 279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cdc31dd15a8f7b32d67ace10797bcd
https://europepmc.org/articles/PMC89377/
https://europepmc.org/articles/PMC89377/
Autor:
Robert W. Buckheit, Julie Russell, Luke A. Pallansch, R J Schultz, W G Brouwer, T L Kinjerski, W A Harrison, D C Dao, Tracy L. Stup, Valerie Fliakas-Boltz
Publikováno v:
Antimicrobial agents and chemotherapy. 39(12)
A series of compounds related to the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) oxathiin carboxanilide (UC84) were evaluated for activity against the human immunodeficiency virus (HIV) to determine structural requirements for anti-HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8335f17709dbe47f30044c44f7bddbe
https://pubmed.ncbi.nlm.nih.gov/8593008
https://pubmed.ncbi.nlm.nih.gov/8593008