From papers to RDF-based integration of physicochemical data and adverse outcome pathways for nanomaterials

Autor: Jeaphianne P. M. van Rijn, Marvin Martens, Ammar Ammar, Mihaela Roxana Cimpan, Valerie Fessard, Peter Hoet, Nina Jeliazkova, Sivakumar Murugadoss, Ivana Vinković Vrček, Egon L. Willighagen

Publikováno v: Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-15 (2024)

Abstract Adverse Outcome Pathways (AOPs) have been proposed to facilitate mechanistic understanding of interactions of chemicals/materials with biological systems. Each AOP starts with a molecular initiating event (MIE) and possibly ends with adverse

Externí odkaz: https://doaj.org/article/72dd282e70fd40a5b849f43a37f053b1

Current status and future challenges of genotoxicity OECD Test Guidelines for nanomaterials: a workshop report

Autor: Shareen H Doak, Cristina Andreoli, Michael J Burgum, Qasim Chaudhry, Eric A J Bleeker, Cecilia Bossa, Josefa Domenech, Damjana Drobne, Valerie Fessard, Nina Jeliazkova, Eleonora Longhin, Elise Rundén-Pran, Maciej Stepnik, Naouale El Yamani, Julia Catalán, Maria Dusinska

Publikováno v: Mutagenesis

Genotoxicity testing for nanomaterials remains challenging as standard testing approaches require some adaptation, and further development of nano-specific OECD Test Guidelines (TGs) and Guidance Documents (GDs) are needed. However, the field of geno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1eb13aabc0fe6140a2b8cb16d3654ad
https://hdl.handle.net/11250/3079665

Environmental considerations and current status of grouping and regulation of engineered nanomaterials

Autor: Harald R. Tschiche, Frank S. Bierkandt, Otto Creutzenberg, Valerie Fessard, Roland Franz, Bernd Giese, Ralf Greiner, Karl‑Heinz Haas, Andrea Haase, Andrea Hartwig, Kerstin Hund‑Rinke, Pauline Iden, Charlotte Kromer, Katrin Loeschner, Diana Mutz, Anastasia Rakow, Kirsten Rasmussen, Hubert Rauscher, Hannes Richter, Janosch Schoon, Otmar Schmid, Claudia Som, Günter E. M.Tovar, Paul Westerhoff, Wendel Wohlleben, Andreas Luch, Peter Laux

Publikováno v: Tschiche, H R, Bierkandt, F S, Creutzenberg, O, Fessard, V, Franz, R, Giese, B, Greiner, R, Haas, K-H, Haase, A, Hartwig, A, Hund-Rinke, K, Iden, P, Kromer, C, Loeschner, K, Mutz, D, Rakow, A, Rasmussen, K, Rauscher, H, Richter, H, Schoon, J, Schmid, O, Som, C, Tovar, G E M, Westerhoff, P, Wohlleben, W, Luch, A & Laux, P 2022, ' Environmental considerations and current status of grouping and regulation of engineered nanomaterials ', Environmental Nanotechnology, Monitoring and Management . https://doi.org/10.1016/j.enmm.2022.100707
Environmental Nanotechnology, Monitoring and Management, 18, Art.-Nr.: 100707

This article reviews the current status of nanotechnology with emphasis on application and related environmental considerations as well as legislation. Application and analysis of nanomaterials in infrastructure (construction, building coatings, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6855153e1e5d32ac6f08b125f9c9f28
https://orbit.dtu.dk/en/publications/e130a369-a1cf-49ef-a9ed-f19b0bccdc7a

New Approach Methods to Assess the Enteropathogenic Potential of Strains of the Bacillus cereus Group, including Bacillus thuringiensis

Autor: Arnaud Fichant, Rachelle Lanceleur, Salma Hachfi, Alexandra Brun-Barale, Anne-Louise Blier, Olivier Firmesse, Armel Gallet, Valérie Fessard, Mathilde Bonis

Publikováno v: Foods, Vol 13, Iss 8, p 1140 (2024)

Bacillus cereus (Bc) is a wide group of Gram-positive and spore-forming bacteria, known to be the etiological agents of various human infections, primarily food poisoning. The Bc group includes enteropathogenic strains able to germinate in the digest

Externí odkaz: https://doaj.org/article/203c02e5d0ac4754a485a9d13032d526

Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines

Autor: Pégah Jalili, Benjamin-Christoph Krause, Rachelle Lanceleur, Agnès Burel, Harald Jungnickel, Alfonso Lampen, Peter Laux, Andreas Luch, Valérie Fessard, Kevin Hogeveen

Publikováno v: Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-20 (2022)

Abstract Background TiO2 nanomaterials (NMs) are present in a variety of food and personal hygiene products, and consumers are exposed daily to these NMs through oral exposition. While the bulk of ingested TiO2 NMs are eliminated rapidly in stool, a

Externí odkaz: https://doaj.org/article/fdc0619b8ed04116bbc117947356bbd6