Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Valerie F, Crepin"'
Autor:
James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation o
Externí odkaz:
https://doaj.org/article/b6965592be8f4c16ab3622e53a3e14e5
Autor:
Caroline Mullineaux-Sanders, James W. Collins, David Ruano-Gallego, Maayan Levy, Meirav Pevsner-Fischer, Izabela T. Glegola-Madejska, Agnes M. Sågfors, Joshua L.C. Wong, Eran Elinav, Valerie F. Crepin, Gad Frankel
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3381-3389 (2017)
Summary: We investigated the role of commensals at the peak of infection with the colonic mouse pathogen Citrobacter rodentium. Bioluminescent and kanamycin (Kan)-resistant C. rodentium persisted avirulently in the cecal lumen of mice continuously tr
Externí odkaz:
https://doaj.org/article/7ea88cecb2fd495fb66456bd2dcd639d
Autor:
Cedric N Berger, Valerie F Crepin, Theodoros I Roumeliotis, James C Wright, Nicolas Serafini, Meirav Pevsner-Fischer, Lu Yu, Eran Elinav, James P Di Santo, Jyoti S Choudhary, Gad Frankel
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007406 (2018)
Infection with Citrobacter rodentium triggers robust tissue damage repair responses, manifested by secretion of IL-22, in the absence of which mice succumbed to the infection. Of the main hallmarks of C. rodentium infection are colonic crypt hyperpla
Externí odkaz:
https://doaj.org/article/3eb206d205fa466db808ba509a30b60a
Autor:
James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The original version of this Article contained an error in the spelling of the author David Ruano-Gallego, which was incorrectly given as David R. Gallego. This has now been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/3c7d3a9004e84e9fa8e7699baf6f939b
Autor:
Cedric N. Berger, Valerie F. Crepin, Kobi Baruch, Aurelie Mousnier, Ilan Rosenshine, Gad Frankel
Publikováno v:
mBio, Vol 3, Iss 5 (2012)
ABSTRACT Translocation of effector proteins via a type III secretion system (T3SS) is a widespread infection strategy among Gram-negative bacterial pathogens. Each pathogen translocates a particular set of effectors that subvert cell signaling in a w
Externí odkaz:
https://doaj.org/article/bb00251f42bf4da3a34ef5612c0ef42c
Publikováno v:
mBio, Vol 3, Iss 1 (2012)
ABSTRACT Rho GTPases are important regulators of many cellular processes. Subversion of Rho GTPases is a common infection strategy employed by many important human pathogens. Enteropathogenic Escherichia coli and enterohemorrhagic Escherichia coli (E
Externí odkaz:
https://doaj.org/article/91d6ca35fe4947ffb1da6d305ae018a5
Autor:
Richard Bulgin, Ana Arbeloa, David Goulding, Gordon Dougan, Valerie F Crepin, Benoit Raymond, Gad Frankel
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000683 (2009)
Enteropathogenic Escherichia coli (EPEC) strains are defined as extracellular pathogens which nucleate actin rich pedestal-like membrane extensions on intestinal enterocytes to which they intimately adhere. EPEC infection is mediated by type III secr
Externí odkaz:
https://doaj.org/article/a03459f130174481ab00fd0ef277f90f
Autor:
Melanie A, McDowell, Alexander Mp, Byrne, Elli, Mylona, Rebecca, Johnson, Agnes, Sagfors, Valerie F, Crepin, Susan, Lea, Gad, Frankel
Publikováno v:
Life Science Alliance
Salmonella Typhi is estimated to cause 100,000–200,000 deaths annually, yet its infection strategy remains elusive. This article reports of the first Typhi-specific effector, which has an E3/E4 ubiquitin ligase activity and can uniquely bind K48- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34f5f2500fdd10facd43832f0ff54e14
https://pubmed.ncbi.nlm.nih.gov/31142637
https://pubmed.ncbi.nlm.nih.gov/31142637
Publikováno v:
Nature Protocols. 11:1851-1876
Infection of mice with Citrobacter rodentium is a robust model to study bacterial pathogenesis, mucosal immunology, the health benefits of probiotics and the role of the microbiota during infection. C. rodentium was first isolated by Barthold from an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea75177c1ff284dfe39549096c9b351e
https://doi.org/10.1038/nprot.2016.100
https://doi.org/10.1038/nprot.2016.100
Autor:
Pawel Herzyk, David Ruano-Gallego, Gillian Douce, James P. R. Connolly, Gad Frankel, Sabrina L. Slater, Robert J. Goldstone, Valerie F. Crepin, David Smith, Nicky O’Boyle, Andrew J. Roe
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Niche-adaptation of a bacterial pathogen hinges on the ability to recognize the complexity of signals from the environment and integrate that information with the regulation of genes critical for infection. Here we report the transcriptome of the att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60837fd87feb9818bd2c52026de28796
http://europepmc.org/articles/PMC6265335
http://europepmc.org/articles/PMC6265335