Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Valerie Dardalhon"'
Autor:
Jean Nakhle, Khattar Khattar, Tülin Özkan, Adel Boughlita, Daouda Abba Moussa, Amelie Darlix, Frédérique Lorcy, Valérie RIGAU, Luc BAUCHET, Sabine Gerbal-Chaloin, Martine Daujat-Chavanieu, Floriant Bellvert, Laurent Turchi, Thierry Virolle, Jean-Philippe Hugnot, Nicolas Buisine, Mireille Galloni, Valerie Dardalhon, Anne-Marie Rodriguez, Marie-Luce Vignais
Publikováno v:
Cancer Research Communications
Cancer Research Communications, 2023, 3 (6), pp.1041-1056. ⟨10.1158/2767-9764.CRC-23-0144⟩
Cancer Research Communications, 2023, 3, pp.1041-1056. ⟨10.1158/2767-9764.crc-23-0144⟩
Cancer Research Communications, 2023, 3 (6), pp.1041-1056. ⟨10.1158/2767-9764.CRC-23-0144⟩
Cancer Research Communications, 2023, 3, pp.1041-1056. ⟨10.1158/2767-9764.crc-23-0144⟩
International audience; Glioblastomas (GBM) are heterogeneous tumors with high metabolic plasticity. Their poor prognosis is linked to the presence of glioblastoma stem cells (GSC), which support resistance to therapy, notably to temozolomide (TMZ).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82ca59d992aa68ebf144b2b728720ed
https://hal.science/hal-04154698
https://hal.science/hal-04154698
Autor:
Marie-Luce Vignais, Anne-Marie Rodriguez, Valerie Dardalhon, Mireille Galloni, Nicolas Buisine, Jean-Philippe Hugnot, Thierry Virolle, Laurent Turchi, Floriant Bellvert, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin, Luc BAUCHET, Valérie RIGAU, Frédérique Lorcy, Amelie Darlix, Daouda Abba Moussa, Adel Boughlita, Tülin Özkan, Khattar Khattar, Jean Nakhle
Effects of MSC mitochondria on GSCs metabolic response to TMZ (A, B) GSC mitochondrial mass and ROS production. FACS analysis of MitoTracker and MitoSox-labeled GSCs after the acquisition of MSC mitochondria and TMZ treatment (24 hr). (A) Mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8796aadcf2cdfb3e2bc1eadc68de8a
https://doi.org/10.1158/2767-9764.23192215
https://doi.org/10.1158/2767-9764.23192215
Autor:
Marie-Luce Vignais, Anne-Marie Rodriguez, Valerie Dardalhon, Mireille Galloni, Nicolas Buisine, Jean-Philippe Hugnot, Thierry Virolle, Laurent Turchi, Floriant Bellvert, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin, Luc BAUCHET, Valérie RIGAU, Frédérique Lorcy, Amelie Darlix, Daouda Abba Moussa, Adel Boughlita, Tülin Özkan, Khattar Khattar, Jean Nakhle
TMZ dose-response assay Caspase-GloⓇ 3/7 assay Cytotox assay Extracellular Flux Assays Cell Proliferation Western Blot Flow Cytometry Metabolite usage Mitoplates Mass Spectrometry Quantification 13C stable isotope tracing experiments Preparation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5721f3708ee485a20a9e29d39d09e8b7
https://doi.org/10.1158/2767-9764.23192200.v1
https://doi.org/10.1158/2767-9764.23192200.v1
Autor:
Marie-Luce Vignais, Anne-Marie Rodriguez, Valerie Dardalhon, Mireille Galloni, Nicolas Buisine, Jean-Philippe Hugnot, Thierry Virolle, Laurent Turchi, Floriant Bellvert, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin, Luc BAUCHET, Valérie RIGAU, Frédérique Lorcy, Amelie Darlix, Daouda Abba Moussa, Adel Boughlita, Tülin Özkan, Khattar Khattar, Jean Nakhle
Cocultures of red MitoTracker-labeled MSCs and green CellTracker-labeled GSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0323551ad7d7b898ed4438cdfccee65a
https://doi.org/10.1158/2767-9764.23192197.v1
https://doi.org/10.1158/2767-9764.23192197.v1
Autor:
Marie-Luce Vignais, Anne-Marie Rodriguez, Valerie Dardalhon, Mireille Galloni, Nicolas Buisine, Jean-Philippe Hugnot, Thierry Virolle, Laurent Turchi, Floriant Bellvert, Martine Daujat-Chavanieu, Sabine Gerbal-Chaloin, Luc BAUCHET, Valérie RIGAU, Frédérique Lorcy, Amelie Darlix, Daouda Abba Moussa, Adel Boughlita, Tülin Özkan, Khattar Khattar, Jean Nakhle
Glioblastomas (GBM) are heterogeneous tumors with high metabolic plasticity. Their poor prognosis is linked to the presence of glioblastoma stem cells (GSCs), which support resistance to therapy, notably to temozolomide (TMZ). Mesenchymal stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3920829ce074ee71aeddfb94bb7003f0
https://doi.org/10.1158/2767-9764.c.6664816.v1
https://doi.org/10.1158/2767-9764.c.6664816.v1
Autor:
Pedro Gonzalez-Menendez, Ira Phadke, Meagan E Olive, Axel Joly, Julien Papoin, Hongxia Yan, Jérémy Galtier, Jessica Platon, Sun Woo Sophie Kang, Kathy L. McGraw, Marie Daumur, Marie Pouzolles, Taisuke Kondo, Stéphanie Boireau, Franciane Paul, David J Young, Sylvain Lamure, Raghavendra G Mirmira, Anu Narla, Guillaume Cartron, Cynthia E. Dunbar, Myriam Boyer-Clavel, Natalie Porat-Shliom, Valerie Dardalhon, Valerie S Zimmermann, Marc Sitbon, Thomas Dever, Narla Mohandas, Lydie M Da Costa, Namrata D. Udeshi, Lionel Blanc, Sandrina Kinet, Naomi Taylor
Publikováno v:
Blood.
Metabolic programs contribute to hematopoietic stem and progenitor cell (HSPC) fate, but it is not known whether the metabolic regulation of protein synthesis controls HSPC differentiation. Here, we show that SLC7A1/CAT1-dependent arginine uptake and
Autor:
Josquin Moraly, Taisuke Kondo, Mehdi Benzaoui, Justyn DuSold, Sohan Talluri, Marie C. Pouzolles, Christopher Chien, Valérie Dardalhon, Naomi Taylor
Publikováno v:
Molecular Oncology, Vol 18, Iss 7, Pp 1695-1718 (2024)
Tumor‐infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T cells have demonstrated remarkable success in the treatment of relapsed/refractory melanoma and hematological malignancies, respectively. These treatments have marked a piv
Externí odkaz:
https://doaj.org/article/708332c6de7f4a75b557c9cbb7ea8d26
Autor:
Julie Perrault, Anais Rivière, Chloe Goldsmith, Jonas Dehairs, Cédric Mongellaz, Laurent Yvan-Charvet, Naomi Taylor, Valérie S. Zimmermann, Saverio Tardito, Maria I. Matias, Valerie Dardalhon, Océane Delos, Amir Foroushani, Kandice R. Levental, Stefan A. Muljo, Sandrina Kinet, Ilya Levental, Hector Hernandez-Vargas, Ali Talebi, Jean-Charles Portais, Justine Bertand-Michel, Madeline Wong, Ameeta Kelekar, Julien C. Marie, Johannes V. Swinnen, Carmen S M Yong, Erdinc Sezgin
Publikováno v:
Cell Reports
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Cell Reports, 2021, 37 (5), pp.109911. ⟨10.1016/j.celrep.2021.109911⟩
Cell Rep
Cell Reports, Vol 37, Iss 5, Pp 109911-(2021)
Suppressive regulatory T cell (Treg) differentiation is controlled by diverse immunometabolic signaling pathways and intracellular metabolites. Here we show that cell-permeable α-ketoglutarate (αKG) alters the DNA methylation profile of naive CD4 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0285e83f2c785c903977fe07dec51
https://lirias.kuleuven.be/handle/20.500.12942/691431
https://lirias.kuleuven.be/handle/20.500.12942/691431
Autor:
Anne Sirvent, Claire Lozano, Cédric Mongellaz, Guillaume Cartron, Hanane Guedon, François Van Laethem, Adeline Quintard, Mehdi Benzaoui, John De Vos, Aurélie Conte, Laura Platon, Jean-Jacques Tudesq, Delphine De Verbizier, Tarik Kanouni, Xavier Ayrignac, Patrice Ceballos, Chris Serrand, Mickael François, Emmanuelle Tchernonog, Eve Gehlkopf, Naomi Taylor, Valerie Dardalhon, Sylvain Lamure, Caroline Bret, Charles Herbaux, Philippe Quittet
Publikováno v:
Cancers, Vol 13, Iss 4279, p 4279 (2021)
Cancers
Cancers, MDPI, 2021, 13 (17), pp.4279. ⟨10.3390/cancers13174279⟩
Volume 13
Issue 17
Cancers
Cancers, MDPI, 2021, 13 (17), pp.4279. ⟨10.3390/cancers13174279⟩
Volume 13
Issue 17
CD19-directed CAR T-cells have been remarkably successful in treating patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and transformed follicular lymphoma (t-FL). In this cohort study, we treated 60 patients with axicabta
Autor:
Marc Sitbon, Michaela Fontenay, Marie Daumur, Julien Papoin, Naomi Taylor, Hongxia Yan, Ira Phadke, Anne-Sophie Dumé, Sandrina Kinet, Narla Mohandas, Valérie S. Zimmermann, Phuong-Nhi Bories, Xiuli An, Ruhi Deshmukh, Manuela Romano, Pedro Gonzalez-Menendez, Xiaoli Qu, Valerie Dardalhon, Cédric Mongellaz, Saverio Tardito, Patrick G. Gallagher, Leal Oburoglu, Lionel Blanc
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2021, 34 (5), pp.108723. ⟨10.1016/j.celrep.2021.108723⟩
Cell Rep
Cell Reports, Elsevier Inc, 2021, 34 (5), pp.108723. ⟨10.1016/j.celrep.2021.108723⟩
Cell Rep
The metabolic changes controlling the stepwise differentiation of hematopoietic stem and progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that HSPC development to an erythroid-committed proerythroblast results in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ccb8919a4bd55b40eb15cb7db34acc
https://hal.archives-ouvertes.fr/hal-03161590
https://hal.archives-ouvertes.fr/hal-03161590