Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Valerie D. Myers"'
Autor:
Valerie D. Myers, PhD, Gavin P. Landesberg, BS, Marcia L. Bologna, BA, Marc J. Semigran, MD, Arthur M. Feldman, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 7, Iss 9, Pp 951-953 (2022)
Externí odkaz:
https://doaj.org/article/80d35a8dc9f04220a4f6ed022ce9646f
Autor:
Thomas G. Martin, Valerie D. Myers, Praveen Dubey, Shubham Dubey, Edith Perez, Christine S. Moravec, Monte S. Willis, Arthur M. Feldman, Jonathan A. Kirk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Decreased expression of BAG3 in the heart is associated with contractile dysfunction and heart failure. Here the authors show that this is due to decreased BAG3-dependent sarcomere protein turnover, which impairs mechanical function, and that sarcome
Externí odkaz:
https://doaj.org/article/e8b11b6fcce64e39a9fa3c8e82869801
Autor:
Valerie D. Myers, MS, Joseph M. McClung, PhD, JuFang Wang, MD, Farzaneh G. Tahrir, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Christopher H. Kontos, MD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 1, Pp 122-131 (2018)
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy;
Externí odkaz:
https://doaj.org/article/33d9e8f9566344c191444dc53631ac00
Autor:
Tijana Knezevic, PhD, Valerie D. Myers, MS, Feifei Su, MD, PhD, JuFang Wang, MD, Jianliang Song, MD, PhD, Xue-Qian Zhang, MD, Erhe Gao, MD, PhD, Guofeng Gao, MD, PhD, Muniswamy Madesh, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Kristen N. Weiner, BS, Joseph Rabinowitz, PhD, Frederick V. Ramsey, PhD, Douglas G. Tilley, PhD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 647-656 (2016)
Mutations in Bcl-2–associated athanogene 3 (BAG3) were associated with skeletal muscle dysfunction and dilated cardiomyopathy. Retro-orbital injection of an adeno-associated virus serotype 9 expressing BAG3 (rAAV9-BAG3) significantly (p < 0.0001) i
Externí odkaz:
https://doaj.org/article/70f170720da34f2985f48ff26cb0cbfd
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 10 (2019)
Externí odkaz:
https://doaj.org/article/3b3e0ecbb5a84a4ba520af4c235e7422
Autor:
JuFang Wang, Dhadendra Tomar, Thomas G. Martin, Shubham Dubey, Praveen K. Dubey, Jianliang Song, Gavin Landesberg, Michael G. McCormick, Valerie D. Myers, Salim Merali, Carmen Merali, Bonnie Lemster, Charles F. McTiernan, Kamel Khalili, Muniswamy Madesh, Joseph Y. Cheung, Jonathan A. Kirk, Arthur M. Feldman
Publikováno v:
JACC: Basic to Translational Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::610677ec5eded2e07ebe578bc967dd93
https://doi.org/10.1016/j.jacbts.2022.12.013
https://doi.org/10.1016/j.jacbts.2022.12.013
Autor:
Joseph Y. Cheung, Jianliang Song, Kamel Khalili, Arthur M. Feldman, Jennifer Gordon, Xue-Qian Zhang, Dhanendra Tomar, JuFang Wang, Glenn S. Gerhard, Valerie D. Myers
Publikováno v:
J Card Fail
Background We reported 3 novel nonsynonymous single nucleotide variants of Bcl2-associated athanogene 3 (BAG3) in African Americans with heart failure (HF) that are associated with a 2-fold increase in cardiac events (HF hospitalization, heart transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c8dceea7f8ef1385f509265b0a973f
https://doi.org/10.1016/j.cardfail.2020.09.009
https://doi.org/10.1016/j.cardfail.2020.09.009
Autor:
Kamel Khalili, Joseph Y. Cheung, Manish K. Gupta, JuFang Wang, Joseph M. McClung, Farzaneh G. Tahrir, Christopher H. Kontos, Jennifer Gordon, Valerie D. Myers, Arthur M. Feldman
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 1, Pp 122-131 (2018)
The B-cell lymphoma 2–associated anthanogene (BAG3) protein is expressed most prominently in the heart, the skeletal muscle, and in many forms of cancer. In the heart, it serves as a co-chaperone with heat shock proteins in facilitating autophagy;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd67a703fbb67af8f0aec78000b7ad8
https://doi.org/10.1016/j.jacbts.2017.09.009
https://doi.org/10.1016/j.jacbts.2017.09.009
Autor:
Guofeng Gao, Jennifer Gordon, Feifei Su, Joseph Y. Cheung, Muniswamy Madesh, Jianliang Song, Joseph E. Rabinowitz, Valerie D. Myers, Erhe Gao, Manish K. Gupta, Kamel Khalili, Frederick V. Ramsey, Douglas G. Tilley, Tijana Knezevic, Xue-Qian Zhang, JuFang Wang, Kristen N. Weiner, Arthur M. Feldman
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 647-656 (2016)
The present study was undertaken to test the hypothesis that gene delivery of BCL2-Associated Athanogene 3 (BAG3) to the heart of mice with left ventricular dysfunction secondary to a myocardial infarction could enhance cardiac performance.BAG3 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b151cd79c22661fac4c499de5756f4c
https://doi.org/10.1016/j.jacbts.2016.08.008
https://doi.org/10.1016/j.jacbts.2016.08.008
Publikováno v:
Circulation Research. 125
Bcl-2-associated athanogene 3 (BAG3) is an adaptor protein often associated with protein quality control. In the heart, decreased BAG3 expression is linked to dilated cardiomyopathy. Mutations to BAG3 can result in myofibrillar disarray, indicating a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40280089cce24dc62c16f786dca28b15
https://doi.org/10.1161/res.125.suppl_1.909
https://doi.org/10.1161/res.125.suppl_1.909