Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Valerie Chun Ling Lin"'
Autor:
Wing Shan Yu, Li Guan, Shawn Zheng Kai Tan, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Valerie Chun Ling Lin, Lee Wei Lim
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 6, Pp 698-703 (2022)
Objective(s): The involvement of tetratricopeptide repeat domain 9A (TTC9A) in anxiety-like behaviors through estrogen action has been reported in female mice, this study further investigated its effects on social anxiety and aggressive behaviors.Mat
Externí odkaz:
https://doaj.org/article/2bf0ea4292564fe5adff19b2987b2889
Autor:
Chew Leng Lim, Yu Zuan Or, Zoe Ong, Hwa Hwa Chung, Hirohito Hayashi, Smeeta Shrestha, Shunsuke Chiba, Feng Lin, Valerie Chun Ling Lin
Publikováno v:
eLife, Vol 9 (2020)
There is strong evidence that the pro-inflammatory microenvironment during post-partum mammary involution promotes parity-associated breast cancer. Estrogen exposure during mammary involution drives tumor growth through neutrophils’ activity. Howev
Externí odkaz:
https://doaj.org/article/9918b552aa5847058495917b5e436015
Autor:
Yu Zuan Or, Valerie Chun Ling Lin, YS Chan, Thomas Lufkin, Lee Wei Lim, Wing Shan Yu, Smeeta Shrestha, Li Guan
Publikováno v:
Brain Research Bulletin. 157:162-168
The involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd843a15589719daf1c82002ff78ff8a
https://doi.org/10.1016/j.brainresbull.2020.02.004
https://doi.org/10.1016/j.brainresbull.2020.02.004
Autor:
Valerie Chun Ling Lin, Chew Leng Lim
Publikováno v:
BMC Cancer
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Background Neutrophils are important for immune surveillance of tumour cells. Neutrophils may also be epigenetically programmed in the tumour microenvironment to promote tumour progression. In addition to the commonly known high-density neutrophils (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eb0ad3d80be8377d95697bfdec4db6
http://europepmc.org/articles/PMC8436517
http://europepmc.org/articles/PMC8436517
Autor:
Clara Ying Bei Low, Chingli Lee, Michelle G.K. Tan, Valerie Chun Ling Lin, Adrian Kian Long Lee, Frances Ting Wei Lim, Juliette Min Huey Lo
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46a7263f442ba2c8a09d3760afc9731
https://doi.org/10.1002/alz.040149
https://doi.org/10.1002/alz.040149
Autor:
Hwa Hwa Chung, Hirohito Hayashi, Feng Lin, Zoe Ong, Shunsuke Chiba, Chew Leng Lim, Smeeta Shrestha, Valerie Chun Ling Lin, Yu Zuan Or
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
There is strong evidence that the pro-inflammatory microenvironment during post-partum mammary involution promotes parity-associated breast cancer. Estrogen exposure during mammary involution drives tumor growth through neutrophils' activity. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc8e1f5f1fd8e44b0dd24d994cc95ee
https://hdl.handle.net/10356/144610
https://hdl.handle.net/10356/144610
Autor:
Valerie Chun Ling Lin, Jonathan Göke, Susana Geifman-Shochat, Lars Nordenskiöld, Jong Fu Wong, Kuan Pern Tan, I-hsin Su, Engin Cukuroglu, Hwa Hwa Chung, Abdollah Allahverdi, Mallur S. Madhusudhan, Yin Hoe Yau, Nandini Venkatesan
Publikováno v:
Oncogene. 37:461-477
Recently, we reported that the histone methyltransferase, EZH2, controls leukocyte migration through interaction with the cytoskeleton remodeling effector, VAV, and direct methylation of the cytoskeletal regulatory protein, Talin. However, it is uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb467042972b31ea9c0e4314a766894
https://doi.org/10.1038/onc.2017.309
https://doi.org/10.1038/onc.2017.309
Publikováno v:
Biochimica et biophysica acta. Gene regulatory mechanisms. 1862(4)
The activation functions AF1 and AF2 of nuclear receptors mediate the recruitment of coregulators in gene regulation. AF1 is mapped to the highly variable and intrinsically unstructured N terminal domain and AF2 lies in the conserved ligand binding d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e6220d231385b204ca6dfdcf2537c
https://pubmed.ncbi.nlm.nih.gov/30716532
https://pubmed.ncbi.nlm.nih.gov/30716532
Autor:
Valerie Chun Ling Lin, Fiona Tay, Naihsuan Guy, Paola Ramos, Marc B. Cox, Yu Zuan Or, Thomas Lufkin, Petra Kraus, Yenni A. Garcia, Smeeta Shrestha, Yang Sun
Publikováno v:
International Journal of Biological Sciences
Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone. It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A. The objectives of this study were to establish a Ttc9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a80dac634bc2d3c32b6e99fd487d9a
http://europepmc.org/articles/PMC4366642
http://europepmc.org/articles/PMC4366642