Výsledky vyhledávání - "Valerie Barbié"

A comparative integrated transcript analysis and functional characterization of differential mechanisms for induction of liver hypertrophy in the rat

Autor: Alexander Amberg, Maximilian Sieber, Laura Suter, Willem G. Schoonen, Nicolas Sajot, Diane McCarthy, Kirstin Meyer, Hans Gmuender, Arnd Brandenburg, Eric Boitier, Marian Raschke, Craig E. Thomas, Valerie Barbié, Albrecht Gruhler, Arne Blichenberg, Bjoern Riefke

Publikováno v: Toxicology and Applied Pharmacology. 252:85-96

The main goal of the present work was to better understand the molecular mechanisms underlying liver hypertrophy (LH), a recurrent finding observed following acute or repeated drug administration to animals, using transcriptomic technologies together

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8429e467c1445343f26443640a3c21
https://doi.org/10.1016/j.taap.2011.01.021

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Characterization of immune cell subsets during the active phase of multiple sclerosis reveals disease and c-Jun N-terminal kinase pathway biomarkers

Autor: Patrizia Tavano, Beatrice Greco, Jean Pierre Gotteland, Ehud Hauben, Paola Zaratin, Chiara Ferrandi, Gianvito Martino, Valerie Barbié, Giancarlo Comi, Mara Fortunato, Maurizio F. Mariani, Roberto Furlan, Fabien Richard

Publikováno v: Multiple Sclerosis Journal. 17:43-56

Background:Autoimmune activation and deregulated apoptosis of T lymphocytes are involved in multiple sclerosis (MS). c-Jun N-terminal kinase (JNK) plays a role in T-cell survival and apoptosis. Objectives:The aim of this work was to investigate the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90377b2c27ea2d9d83305d6c4e6ac59d
https://doi.org/10.1177/1352458510381258

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Akademický článek

Initial presentation, management and follow-up data of 33 treated patients with hereditary tyrosinemia type 1 in the absence of newborn screening

Autor: Hela Hajji, Apolline Imbard, Anne Spraul, Ludmia Taibi, Valérie Barbier, Dalila Habes, Anaïs Brassier, Jean-Baptiste Arnoux, Juliette Bouchereau, Samia Pichard, Samira Sissaoui, Florence Lacaille, Muriel Girard, Dominique Debray, Pascale de Lonlay, Manuel Schiff

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 33, Iss , Pp 100933- (2022)

Hereditary tyrosinemia type 1 (HT1) is a rare autosomal recessive disorder of phenylalanine and tyrosine catabolism due to a deficiency of fumarylacetoacetate hydrolase. HT1 has a large clinical spectrum with acute forms presenting before six months

Externí odkaz: https://doaj.org/article/06ee16d9c5f84e49b379a7616bb8c55f

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Akademický článek

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

Autor: Valerie Barbier, Johanna Erbani, Corrine Fiveash, Julie M. Davies, Joshua Tay, Michael R. Tallack, Jessica Lowe, John L. Magnani, Diwakar R. Pattabiraman, Andrew C. Perkins, Jessica Lisle, John E. J. Rasko, Jean-Pierre Levesque, Ingrid G. Winkler

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)

The cell adhesion molecule E-selectin regulates haematopoietic stem cell self-renewal in the bone marrow vascular niche. Here, the authors show E-selectin adhesion directly induces survival signaling in acute myeloid leukaemia and therapeutic inhibit

Externí odkaz: https://doaj.org/article/7dde84bbf79f4a748ecf6d1fab0d7161

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Akademický článek

Diagnosis and phenotypic assessment of trimethylaminuria, and its treatment with riboflavin: 1H NMR spectroscopy and genetic testing

Autor: Nadia Bouchemal, Lisa Ouss, Anaïs Brassier, Valérie Barbier, Stéphanie Gobin, Laurence Hubert, Pascale de Lonlay, Laurence Le Moyec

Publikováno v: Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-10 (2019)

Abstract Background Trimethylaminuria (TMAU) is a metabolic disorder characterized by the excessive excretion of the malodorous compound trimethylamine (TMA). The diagnosis of TMAU is challenging because this disorder is situated at the boundary betw

Externí odkaz: https://doaj.org/article/e9c6d4b437ca45deb5651b37c9bcf377

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Akademický článek

Enteral tube feeding in patients receiving dietary treatment for metabolic diseases: A retrospective analysis in a large French cohort

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 26, Iss , Pp 100655- (2021)

Context: A strictly controlled diet (often involving enteral tube feeding (ETF)) is part of the treatment of many inherited metabolic diseases (IMDs). Objective: To describe the use of ETF in a large cohort of patients with IMDs. Design: A retrospect

Externí odkaz: https://doaj.org/article/5305a830d5894d958f53a020b67a5820

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Akademický článek

NGS-Based S. aureus Typing and Outbreak Analysis in Clinical Microbiology Laboratories: Lessons Learned From a Swiss-Wide Proficiency Test

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Whole genome sequencing (WGS) enables high resolution typing of bacteria up to the single nucleotide polymorphism (SNP) level. WGS is used in clinical microbiology laboratories for infection control, molecular surveillance and outbreak analyses. Give

Externí odkaz: https://doaj.org/article/c20aa348c6e94d02a156f6cbe0b95785

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Akademický článek

Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner

Autor: Kavita Bisht, Joshua Tay, Rebecca N. Wellburn, Crystal McGirr, Whitney Fleming, Bianca Nowlan, Valerie Barbier, Ingrid G. Winkler, Jean-Pierre Levesque

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

Anemia of inflammation (AI) is the second most prevalent anemia after iron deficiency anemia and results in persistent low blood erythrocytes and hemoglobin, fatigue, weakness, and early death. Anemia of inflammation is common in people with chronic

Externí odkaz: https://doaj.org/article/ff12dcb49dd94ebabbf3b487e364337d

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