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Autor:
Andrew Lombardo, Cécile Sauvanet, David J. McDermitt, Riasat Zaman, Raghuvir Viswanatha, Valerie Awad, Anthony Bretscher, Locke Ezra-Ros Bonomo
Publikováno v:
The Journal of Cell Biology
Zaman and Lombardo et al. characterize cells lacking all ERM proteins or their activating kinases. This reveals that active ERMs are local negative regulators of RhoA necessary to mediate the architecture of the apical domain.
Activated ezrin-ra
Activated ezrin-ra