Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Valerie A. Trabosh"'
Autor:
Valerie A. Trabosh, Dean S. Rosenthal, You-Shin Chen, Cynthia M. Simbulan-Rosenthal, Kyle A. DiVito
Publikováno v:
Carcinogenesis. 35:951-958
The role for the inhibitors of differentiation (Ids) proteins in melanomagenesis has been poorly explored. In other cell types, Ids have been shown to contribute to cell proliferation, migration and angiogenesis and, along with a number of other gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4f6ba3dd9f55e6d5f8006bf7e60c21
https://doi.org/10.1093/carcin/bgt479
https://doi.org/10.1093/carcin/bgt479
Autor:
Dean S. Rosenthal, You-Shin Chen, Yu Chen, Chris Albanese, Kyle A. DiVito, Valerie A. Trabosh, Alain Mauviel, Delphine Javelaud, Cynthia M. Simbulan-Rosenthal
Publikováno v:
Pigment Cell & Melanoma Research. 23:795-808
The list of transforming growth factor-beta (TGF-β)-related proteins in non-canonical TGF-β signaling is growing. Examples include receptor-Smads directing micro-RNA processing and inhibitory-Smads, e.g. Smad7, directing cell adhesion. Human skin g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931e2b756db06765c671a15868bec85b
https://doi.org/10.1111/j.1755-148x.2010.00758.x
https://doi.org/10.1111/j.1755-148x.2010.00758.x
Autor:
Valerie A. Trabosh, Wesley W. Holmes, Brian Keyser, Dean S. Rosenthal, Radharaman Ray, Ahmad Daher, Dana R. Anderson, Betty Benton, Cynthia M. Simbulan-Rosenthal
Publikováno v:
Toxicology. 271:94-99
Sulfur mustard (SM [bis-(2-chloroethyl) sulfide]) is a chemical warfare agent that causes skin blisters presumably due to DNA alkylation and cross-links. We recently showed that SM also induces apoptotic death in cultured normal human bronchial/trach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f46207e4fb44e585b3b86bb07b4f2b3
https://doi.org/10.1016/j.tox.2010.03.008
https://doi.org/10.1016/j.tox.2010.03.008
Autor:
Baltazar D. Aguda, Cynthia M. Simbulan-Rosenthal, Valerie A. Trabosh, Dean S. Rosenthal, Kyle A. DiVito
Publikováno v:
Carcinogenesis. 30:1252-1259
Id2 is a member of the helix-loop-helix (HLH) family of transcription regulators known to antagonize basic HLH transcription factors and proteins of the retinoblastoma tumor suppressor family and is implicated in the regulation of proliferation, diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650cb7827c83e6d9a559b210494efe10
https://doi.org/10.1093/carcin/bgp115
https://doi.org/10.1093/carcin/bgp115
Autor:
Valerie A. Trabosh, Ahmad Daher, W.-C. Chen, Cynthia M. Simbulan-Rosenthal, E. Soeda, D. Gerstel, Dean S. Rosenthal
Publikováno v:
Oncogene. 25:3649-3660
Inhibitor of differentiation/DNA binding (Id) proteins comprise a class of helix-loop-helix transcription factors involved in proliferation, differentiation, apoptosis, and carcinogenesis. We have shown that while Id2 is induced by UVB in primary ker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d78c64d0f6f1464aaf527cbaad43c24
https://doi.org/10.1038/sj.onc.1209407
https://doi.org/10.1038/sj.onc.1209407
Autor:
Ronniel Nazarian, Kenneth J. McPartland, John H. Henson, Katrina L. Schulberg, Andrew R. Burns, Sarah E. Kolnik, Valerie A. Trabosh
Publikováno v:
Molecular Biology of the Cell. 13:1001-1014
The actomyosin purse string is an evolutionarily conserved contractile structure that is involved in cytokinesis, morphogenesis, and wound healing. Recent studies suggested that an actomyosin purse string is crucial for the closure of wounds in singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d99a26c25542872f448186d9913a21
https://doi.org/10.1091/mbc.01-04-0167
https://doi.org/10.1091/mbc.01-04-0167
Autor:
You-Shin Chen, Dean S. Rosenthal, Cynthia M. Simbulan-Rosenthal, Valerie A. Trabosh, Kyle A. DiVito
Publikováno v:
Experimental dermatology. 24(2)
TGF-β and the inhibitors of differentiation (Id) are linked. Smad7 and other TGF-β inhibitors can potently suppress melanomagenesis; however, little work examining Ids has been reported in melanoma, particularly for Id4. Here, we report that Id4, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e64801dd893ae3604efdf56938d468
https://pubmed.ncbi.nlm.nih.gov/25363621
https://pubmed.ncbi.nlm.nih.gov/25363621
Autor:
Yesha Patel, Chris Albanese, Maria Laura Avantaggiati, Dean S. Rosenthal, Milton L. Brown, Paul Sirajuddin, Lymor Ringer, Amanda Brophy, Venkata Mahidhar Yenugonda, Valerie A. Trabosh, Anup K. Ghosh, Kyle A. DiVito, Scott Grindrod, Olga Rodriguez, Michael P. Lisanti
Publikováno v:
Cancer biologytherapy. 10(4)
The 2,6,9-trisubstituted purine group of cyclin dependent kinase inhibitors have the potential to be clinically relevant inhibitors of cancer cell proliferation. We have recently designed and synthesized a novel dansylated analog of purvalanol B, ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d35010f58a29baf549f5da317986a6
https://pubmed.ncbi.nlm.nih.gov/20703097
https://pubmed.ncbi.nlm.nih.gov/20703097
Autor:
Valerie A. Trabosh, Ahmad Daher, Dean S. Rosenthal, Karishma S Amin, Cynthia M. Simbulan-Rosenthal, Kyle A. DiVito
Id3 belongs to the inhibitor of differentiation family of helix-loop-helix transcription factors, important in proliferation, differentiation and apoptosis. We showed that Id3, but not Id2 or Id1, mediates the UVB-sensitization of immortalized kerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d838cf9a83c8e510485015ed15b8727
https://europepmc.org/articles/PMC2759318/
https://europepmc.org/articles/PMC2759318/
Autor:
Ahmad Daher, Dean S. Rosenthal, Cynthia M. Simbulan-Rosenthal, Valerie A. Trabosh, Fnu Tenzin, Takashi Tokino, A Velarde, Feng-Pai Chou
Publikováno v:
Oncogene. 24(35)
Solar ultraviolet B (UVB) acts as both an initiator and promoter in models of multistage skin carcinogenesis. We found that, whereas UVB induces apoptosis in human papillomavirus-16 E6/7-immortalized keratinocytes, it inhibits markers of differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88a3a59170a9805fec2b4607d23bdb8
https://pubmed.ncbi.nlm.nih.gov/16007217
https://pubmed.ncbi.nlm.nih.gov/16007217