Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Valerie A. Siclari"'
Autor:
Ji Zhu, Valerie A Siclari, Fei Liu, Jordan M Spatz, Abhishek Chandra, Paola Divieti Pajevic, Ling Qin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50099 (2012)
Intermittent administration of parathyroid hormone (PTH) dramatically increases bone mass and currently is one of the most effective treatments for osteoporosis. However, the detailed mechanisms are still largely unknown. Here we demonstrate that con
Externí odkaz:
https://doaj.org/article/f9bbf6db7f9044f28c55fd61ab97b01f
Autor:
Valerie A. Siclari, Elena M. Candela, Eiki Koyama, Motomi Enomoto-Iwamoto, Ling Qin, Xianrong Zhang, Abhishek Chandra, Tiao Lin, Ji Zhu, Yumei Li
Publikováno v:
Journal of Biological Chemistry. 288:32229-32240
The epidermal growth factor receptor (EGFR) is an essential player in the development of multiple organs during embryonic and postnatal stages. To understand its role in epiphyseal cartilage development, we generated transgenic mice with conditionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f50afa0d01c714602c128c4ca6ddcd1
https://doi.org/10.1074/jbc.m113.463554
https://doi.org/10.1074/jbc.m113.463554
Publikováno v:
Journal of Biological Chemistry. 288:20488-20498
Maintaining bone architecture requires continuous generation of osteoblasts from osteoprogenitor pools. Our previous study of mice with epidermal growth factor receptor (EGFR) specifically inactivated in osteoblast lineage cells revealed that EGFR st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945b7d2487410471e3358a33f3ff0dc2
https://doi.org/10.1074/jbc.m112.447250
https://doi.org/10.1074/jbc.m112.447250
Autor:
Frank Beier, Shenghui Lan, Holly Dupuis, Ling Qin, Ji Zhu, Eiki Koyama, Valerie A. Siclari, Xianrong Zhang, Motomi Enomoto-Iwamoto
Publikováno v:
Paediatrics Publications
Loss of epidermal growth factor receptor (EGFR) activity in mice alters growth plate development, impairs endochondral ossification, and retards growth. However, the detailed mechanism by which EGFR regulates endochondral bone formation is unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2583ff13f6653a244a9317dbb6dd6ceb
https://doi.org/10.1002/jbmr.502
https://doi.org/10.1002/jbmr.502
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1226
Bone marrow mesenchymal stem cells (MSCs) are promising therapeutic tools for tissue repair and the treatment of a number of human diseases. As a result, there is substantial interest in characterizing and expanding these cells to uncover their thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::004a32ffc2243ca5cecd9bed3cab2375
https://pubmed.ncbi.nlm.nih.gov/25331040
https://pubmed.ncbi.nlm.nih.gov/25331040
Publikováno v:
Methods in Molecular Biology ISBN: 9781493916184
Bone marrow mesenchymal stem cells (MSCs) are promising therapeutic tools for tissue repair and the treatment of a number of human diseases. As a result, there is substantial interest in characterizing and expanding these cells to uncover their thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6902f90df8ceaff1507836eff47945
https://doi.org/10.1007/978-1-4939-1619-1_3
https://doi.org/10.1007/978-1-4939-1619-1_3
Autor:
Xianrong Zhang, Ling Qin, Ji Zhu, Abhishek Chandra, Valerie A. Siclari, Fei Liu, Hyun-Duck Nah, Kentaro Akiyama, Songtao Shi
Long bone is an anatomically complicated tissue with trabecular-rich metaphyses at two ends and cortical-rich diaphysis at the center. The traditional flushing method only isolates mesenchymal progenitor cells from the central region of long bones an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f11211d5ec87cf7cd72f274d45e076
https://europepmc.org/articles/PMC3674849/
https://europepmc.org/articles/PMC3674849/
Autor:
Valerie A. Siclari, Tiao Lin, Xianrong Zhang, Keith A. Cengel, Shenghui Lan, X. Sherry Liu, Abhishek Chandra, Ji Zhu, Ling Qin, Allison R. Altman
Publikováno v:
Bone. 55(2)
Radiation therapy is a common treatment regimen for cancer patients. However, its adverse effects on the neighboring bone could lead to fractures with a great impact on quality of life. The underlying mechanism is still elusive and there is no preven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ad813ba1e6f84342834975efea7cab
https://pubmed.ncbi.nlm.nih.gov/23466454
https://pubmed.ncbi.nlm.nih.gov/23466454
Autor:
Valerie A Siclari
The majority of patients with advanced breast cancer develop bone metastases, which are incurable. Recently, tumor-secreted factors have shown promise as targets for the treatment of bone metastasis. Adrenomedullin (AM) is a breast cancer-secreted pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca97422e541dd1dda7dc590ff14b695d
https://doi.org/10.21236/ada486581
https://doi.org/10.21236/ada486581
Publikováno v:
Metastasis of Breast Cancer ISBN: 9781402058660
Bone is the most common site of breast cancer metastasis. Over eighty percent of patients with advanced breast cancer develop bone metastases. Once breast cancer has spread to bone, the cancer is incurable and patients develop mostly osteolytic, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fde446daec649e75d3232df6f425be5
https://doi.org/10.1007/978-1-4020-5867-7_12
https://doi.org/10.1007/978-1-4020-5867-7_12