Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Valerie A. Porter"'
Autor:
Pedro N. Bernardino, Brad A. Hobson, Sydney L. Huddleston, Peter M. Andrew, Jeremy A. MacMahon, Naomi H. Saito, Valerie A. Porter, Donald A. Bruun, Danielle J. Harvey, Joel R. Garbow, Angie Gelli, Abhijit J. Chaudhari, Pamela J. Lein
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106316- (2023)
Acute organophosphate (OP) intoxication can trigger seizures that progress to status epilepticus (SE), and survivors often develop chronic morbidities, including spontaneous recurrent seizures (SRS). The pathogenic mechanisms underlying OP-induced SR
Externí odkaz:
https://doaj.org/article/cf4eedabf6fd4818801f2e454472f2db
Autor:
Daniel P. Nelson, Valerie A. Porter, Andrea Olschewski, Zhigang Hong, E. Kenneth Weir, Douglas A Peterson
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 286:L15-L22
At birth, associated with the rise in oxygen tension, the pulmonary arteries (PA) dilate and the ductus arteriosus (DA) constricts. Both PA and DA constrict with vasoconstrictors and dilate with vasodilators. They respond in a contrary manner only to
Autor:
George A. Carlson, David N. Cornfield, Valerie A. Porter, Ken Kazama, Costantino Iadecola, Kiyoshi Niwa
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H2417-H2424
Amyloid-beta (A beta)-peptides are involved in the pathophysiology of Alzheimer's dementia. We studied the effects of A beta on selected constrictor responses of cerebral circulation. Mice were anesthetized (by using urethane-chloralose) and equipped
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 25:78-83
Polycyclic aromatic hydrocarbons (PAHs) increase cytosolic Ca(2+) concentration ([Ca(2+)](i)) in lymphocytes and mammary epithelial cells, but little is known regarding their effects on [Ca(2+)](i) in airway epithelium. We hypothesized that benzo[a]p
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 279:L751-L757
To study developmental changes in intracellular calcium handling in pulmonary artery smooth muscle cells (PASMCs), cells were isolated from distal and proximal pulmonary arteries from rabbits at different developmental stages: juvenile (4–6 wk old)
Publikováno v:
American Journal of Physiology-Cell Physiology. 278:C235-C256
Local intracellular Ca2+transients, termed Ca2+sparks, are caused by the coordinated opening of a cluster of ryanodine-sensitive Ca2+release channels in the sarcoplasmic reticulum of smooth muscle cells. Ca2+sparks are activated by Ca2+entry through
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 276:L925-L932
Evidence suggests that nitric oxide (NO) causes perinatal pulmonary vasodilation through K+-channel activation. We hypothesized that this effect worked through cGMP-dependent kinase-mediated activation of Ca2+-activated K+channel that requires releas
Autor:
Thomas Kleppisch, Adrian D. Bonev, Thomas J. Heppner, Andra S. Stevenson, Michael Rubart, Harm J. Knot, Mark T. Nelson, Valerie A. Porter, George C. Wellman, W. J. Lederer, Jonathan H. Jaggar, Maik Gollasch, Guillermo J. Pérez
Publikováno v:
Acta Physiologica Scandinavica. 164:577-587
Local calcium transients ('Ca2+ sparks') are thought to be elementary Ca2+ signals in heart, skeletal and smooth muscle cells. Ca2+ sparks result from the opening of a single, or the coordinated opening of many, tightly clustered ryanodine receptor (
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 261:G585-G591
Intestinal adaptation of glucose transport during streptozocin-induced diabetes in rats was examined using microdensitometric analysis of [3H]phlorizin binding. Results of specific phlorizin binding were correlated with measurements of maximal transp
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 69:1143-1148
Chronic diabetes enhances intestinal absorption of glucose and induces hyperphagia. We examined the enhanced intestinal absorption of glucose in ad libitum-fed rats with streptozocin-induced diabetes mellitus and compared these results with those obt