Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Valerie A. Kelly"'
Autor:
Rosie Morris, Douglas N. Martini, Katrina Ramsey, Valerie E. Kelly, Katrijn Smulders, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated wi
Externí odkaz:
https://doaj.org/article/56b617566f02418bacfaf0ca87b711a1
Autor:
Rosie Morris, Douglas N. Martini, Valerie E. Kelly, Katrijn Smulders, Katrina Ramsey, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100201- (2023)
Background: Gait and balance impairments are among the most troublesome and heterogeneous in Parkinson’s disease (PD). This heterogeneity may, in part, reflect genetic variation. The apolipoprotein E (APOE) gene has three major allelic variants (ε
Externí odkaz:
https://doaj.org/article/3cac717a7a5542b3a906ea0c2ee206cc
Autor:
Douglas N. Martini, Rosie Morris, Valerie E. Kelly, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, John Oakley, Kathleen Poston, Ignacio F. Mata, Karen L. Edwards, Jodi A. Lapidus, Thomas J. Grabowski, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Mobility and sensorimotor inhibition impairments are heterogeneous in Parkinson's disease (PD). Genetics may contribute to this heterogeneity since the apolipoprotein (APOE) ε4 allele and glucocerebrosidase (GBA) gene variants have been
Externí odkaz:
https://doaj.org/article/336eb63f38414cdc9467ccea733af154
Autor:
Douglas N. Martini, Rosie Morris, Graham Harker, Valerie E. Kelly, John G. Nutt, Fay B. Horak
Publikováno v:
Experimental Brain Research. 241:127-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0539ee3675fb4ef98591737980f45dad
https://doi.org/10.1007/s00221-022-06509-1
https://doi.org/10.1007/s00221-022-06509-1
Autor:
Amir, Besharat, Sheri I, Imsdahl, Momona, Yamagami, Nawat, Nhan, Olivia, Bellatin, Samuel A, Burden, Kathleen, Cummer, Sujata D, Pradhan, Valerie E, Kelly
Publikováno v:
Gait & Posture. 92:442-448
Many people with Parkinson disease (PD) experience freezing of gait (FoG), a transient gait disturbance associated with increased fall risk and reduced quality of life. Head-mounted virtual reality (VR) systems allow overground walking and can create
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badad76c1aa6ebc3b9243f266dee8fe8
https://doi.org/10.1016/j.gaitpost.2021.12.013
https://doi.org/10.1016/j.gaitpost.2021.12.013
Publikováno v:
Disability and Rehabilitation. 44:5585-5591
Purpose: Sleep deficits are a common nonmotor symptom of Parkinson disease (PD). People with mild PD also achieve less physical activity (PA) than healthy older adults (HOA), but the relationship b...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b356ba821ad3537b204644fae69b890b
https://doi.org/10.1080/09638288.2021.1940320
https://doi.org/10.1080/09638288.2021.1940320
Autor:
Rosie Morris, Douglas N. Martini, Katrina Ramsey, Valerie E. Kelly, Katrijn Smulders, Amie Hiller, Kathryn A. Chung, Shu-Ching Hu, Cyrus P. Zabetian, Kathleen L. Poston, Ignacio F. Mata, Karen L. Edwards, Jodi Lapidus, Brenna Cholerton, Thomas J. Montine, Joseph F. Quinn, Fay Horak
Publikováno v:
NPJ Parkinson's disease. 8(1)
The extent to which the heterogeneity of gait and balance problems in PD may be explained by genetic variation is unknown. Variants in the glucocerebrosidase (GBA) gene are the strongest known genetic risk factor for PD and are associated with greate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a0a186272c7af06a1b9edbe7d465ae
https://pubmed.ncbi.nlm.nih.gov/35725575
https://pubmed.ncbi.nlm.nih.gov/35725575
Publikováno v:
Phys Occup Ther Geriatr
AIMS: To examine concurrent and construct validity of inertial sensor 360°turn measures in relation with motion capture and mobility assessments in cognitively impaired older adults. METHODS: Data was collected in 31 participants, mean age 85.2 (SD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22efd4cef319977e865ed552980e4c28
https://pubmed.ncbi.nlm.nih.gov/34305253
https://pubmed.ncbi.nlm.nih.gov/34305253
Autor:
Cyrus P. Zabetian, Thomas J. Grabowski, Kathryn A. Chung, Douglas N. Martini, Amie L. Hiller, Shu Ching Hu, Kathleen L. Poston, Joseph F. Quinn, Laurice Yang, Fay B. Horak, Katrijn Smulders, Valerie E. Kelly, Karen L. Edwards, Thomas J. Montine, Rosie Morris, Brenna Cholerton
Publikováno v:
Parkinsonism Relat Disord
Introduction Gait and balance impairments are cardinal features of Parkinson's disease (PD) that require cognitive input. However, the extent to which specific gait and balance characteristics relate to cognition in PD is unclear. In addition, indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210ff5ceaa8ba2280bbf8db18f6cca52
https://doi.org/10.1016/j.parkreldis.2019.06.014
https://doi.org/10.1016/j.parkreldis.2019.06.014
Autor:
Thomas J. Grabowski, Valerie E. Kelly, Rosie Morris, John G. Nutt, Douglas N. Martini, Tara M. Madhyastha, Fay B. Horak
Publikováno v:
Parkinsonism Relat Disord
Mobility deficits, including gait disturbance, balance impairments and falls, are common features of Parkinson's disease (PD) that negatively impact quality of life. Mobility deficits respond poorly to dopaminergic medications, indicating a role for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc6fdc8fb8329abb87ec9b0f8ac7f36
https://doi.org/10.1016/j.parkreldis.2019.02.017
https://doi.org/10.1016/j.parkreldis.2019.02.017