Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Valerie A. Frydrychowski"'
Publikováno v:
The Journal of Organic Chemistry. 66:925-938
A newly designed synthetic entry to the C1-C27 domain of okadaic acid has been developed. This incorporates substantial improvements in the preparations of the key okadaic acid building blocks representing the C3-C8, C9-C14, and C16-C27 portions. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7cc1de3d7b6dd7b2ca6942a3f700a4a
https://doi.org/10.1021/jo001433n
https://doi.org/10.1021/jo001433n
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:647-649
Okadaic acid is a potent inhibitor of select serine/threonine protein phosphatases. The importance of the C28-C38 hydrophobic domain of okadaic acid for inhibition of PP1 and PP2A was investigated. The hydrophobic domain is required but not sufficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391f267312247967a52cd7d650721a21
https://doi.org/10.1016/s0960-894x(01)00026-9
https://doi.org/10.1016/s0960-894x(01)00026-9
Publikováno v:
Journal of Chemical Education. 72:429
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121388e876445df40308ac61b4bfdf98
https://doi.org/10.1021/ed072p429
https://doi.org/10.1021/ed072p429