Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Valerie A Novakovic"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays a crucial role in forming in situ thrombosis, pulmonary dysfunction, and hy
Externí odkaz:
https://doaj.org/article/cd2e18f47dab4caab95b7a5f86f2e877
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications are associated with severe COVID-19 and high mortality. COVID-19 disease is associated with a hyper-inflammatory response (cytokine storm) mediated by the immune
Externí odkaz:
https://doaj.org/article/8a88eb09ce744e698506fd5152adac2d
Autor:
Mengqi Xiang, Xiaoming Wu, Haijiao Jing, Langjiao Liu, Chunxu Wang, Yufeng Wang, Valerie A. Novakovic, Jialan Shi
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with COVID-19 often have hypoxemia, impaired lung function, and abnormal imaging manifestations in acute and convalescent stages. Alveolar inflammation, pulmonary vasculitis, and thromboembolism synergistically damage the blood-air barrier,
Externí odkaz:
https://doaj.org/article/2b84cf37a3fb4a4bb72cd2a52567eda8
Autor:
Langjiao Liu, Haijiao Jing, Xiaoming Wu, Mengqi Xiang, Valerie A. Novakovic, Shuye Wang, Jialan Shi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
The pandemic respiratory illness SARS-CoV-2 has increasingly been shown to be a systemic disease that can also have profound impacts on the cardiovascular system. Although associated cardiopulmonary sequelae can persist after infection, the link betw
Externí odkaz:
https://doaj.org/article/6d7efa308c6b487980665135e158ee99
Autor:
Chengyue Wang, Chengyuan Yu, Haijiao Jing, Xiaoming Wu, Valerie A. Novakovic, Rujuan Xie, Jialan Shi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life leading to an increased burden on the healthcare system, their families and society at large. Possible pathophysiological mechanisms of long COVID include: pers
Externí odkaz:
https://doaj.org/article/3a29832620544b26accf187cf9a48cb0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lung injury may persist during the recovery period of COVID-19 as shown through imaging, six-minute walk, and lung function tests. The pathophysiological mechanisms leading to long COVID have not been adequately explained. Our aim is to investigate t
Externí odkaz:
https://doaj.org/article/ccd048942afe458099ee15dd0536a891
Autor:
Xiaoming Wu, Haijiao Jing, Chengyue Wang, Yufeng Wang, Nan Zuo, Tao Jiang, Valerie A. Novakovic, Jialan Shi
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The intestinal tract, with high expression of angiotensin-converting enzyme 2 (ACE2), is a major site of extrapulmonary infection in COVID-19. During pulmonary infection, the virus enters the bloodstream forming viremia, which infects and damages ext
Externí odkaz:
https://doaj.org/article/72fbe1715d134dc1ab1797920fba2ad4
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Cancer patients have increased SARS-CoV-2 susceptibility and are prone to developing severe COVID-19 infections. The incidence of venous thrombosis is approximately 20% in COVID-19 patients with cancer. It has been suggested that thrombus formation h
Externí odkaz:
https://doaj.org/article/213cab30efea484c8e8e9d8e48defeba
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
As more is learned about the pathophysiological mechanisms of COVID-19, systemic thrombosis has been recognized as being associated with more severe clinical manifestations, mortality and sequelae. As many as 40% of patients admitted to the hospital
Externí odkaz:
https://doaj.org/article/04f65994d5e24b01ab4c797fd28858f8
Autor:
Chunxu Wang, Muxin Yu, Peng Zhou, Baorong Li, Yingmiao Liu, Lixiu Wang, Xiaojing Chen, Jingwen Du, Yufeng Wang, Jinming Zhang, Haijiao Jing, Yiming Feng, Yue Zhang, Yueyue Li, Zengxiang Dong, Shaohong Fang, Valerie A Novakovic, Jin Zhou, Jialan Shi
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102992- (2020)
Background: The role of vascular endothelium in acute promyelocytic leukaemia (APL) remains unknown. We aimed to investigate the mechanisms by which APL cells interact with endothelial cells (ECs) and to further explore how the endothelium affects bl
Externí odkaz:
https://doaj.org/article/9e7215b4572249358ef3e665423ae589