Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Valerie, Meresse"'
Autor:
Yvonne W. S. Jauw, Marc C. Huisman, Tapan K. Nayak, Danielle J. Vugts, Randolph Christen, Valerie Meresse Naegelen, Dominik Ruettinger, Florian Heil, Adriaan A. Lammertsma, Henk M. W. Verheul, Otto S. Hoekstra, Guus A. M. S. van Dongen, C. Willemien Menke-van der Houven van Oordt
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Background Ideally, monoclonal antibodies provide selective treatment by targeting the tumour, without affecting normal tissues. Therefore, antibody imaging is of interest, preferably in early stages of drug development. However, the imaging
Externí odkaz:
https://doaj.org/article/8d731bf420ab4d29a39b50bd3ca1c04f
Autor:
Florence I. Raynaud, Udai Banerji, Paul Workman, Stanley B. Kaye, Johann S. de Bono, Suzanne A. Eccles, Valerie Meresse, Ruediger Rueger, Miro Venturi, Debra J. Skene, Victoria L. Revell, Alexis de haven Brandon, Gary Box, Melanie Valenti, Alan T. Henley, Yasmin J. Asad, Akos Pal, Joo Ern Ang
Time of day variation in metabolites in healthy volunteers and in patients treated with the MEK inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83107465c9a5097e379e6d18c459f627
https://doi.org/10.1158/1535-7163.22508289.v1
https://doi.org/10.1158/1535-7163.22508289.v1
Autor:
Wilfried Ernst Erich Eberhardt, Jan H.M. Schellens, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J.L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Vanesa Lopez-Valverde, Avinash Gupta, Max E. Scheulen, Veronique Dieras, Françoise Kraeber-Bodéré, Patricia Tresca, Mark R. Middleton, Suzanne Leijen
PDF file, 1001K, Methods; Supplementary Table 1 - Temporary dose interruptions due to adverse events; Supplementary Table 2 - Changes in biomarker levels between baseline and Day 15; Supplementary Figure 1: Schematic showing dosing cohorts, DLTs and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7be86e7d7ff6abbb2f08c3c8e17ccc
https://doi.org/10.1158/1078-0432.22452476.v1
https://doi.org/10.1158/1078-0432.22452476.v1
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
PDF file, 130K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006b8947be1db4b35cb0c1be9eb3d2ac
https://doi.org/10.1158/1078-0432.22451105.v1
https://doi.org/10.1158/1078-0432.22451105.v1
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
Purpose: This phase I study assessed the maximum tolerated dose (MTD), dose-limiting toxicities (DLT), safety, pharmacokinetics, pharmacodynamics, and clinical activity of the first-in-class dual MEK/RAF inhibitor, RO5126766.Experimental Design: Init
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbca345e19eeb5455a74ad1913cfe943
https://doi.org/10.1158/1078-0432.c.6522101
https://doi.org/10.1158/1078-0432.c.6522101
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Purpose: CD44, a cell surface glycoprotein, plays important roles in the development, progression, and metastasis of various tumor types. The aim of this study was to investigate how the expression of CD44 isoforms influences the interaction with hya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0471a2b2e86dfb93e268dd809b75cb3d
https://doi.org/10.1158/1078-0432.c.6524757.v1
https://doi.org/10.1158/1078-0432.c.6524757.v1
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Supplementary Methods, Figures (1-6) and Tables (1, 2 and 4). Supplementary Figure 1: Shows how RG7356 blocks binding of CD44-Fc to HA in a concentration dependent manner for two fixed CD44-Fc concentrations. Supplementary Figure 2: Shows hyaluronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cdc6774cab1b66f39990c9e3e50834
https://doi.org/10.1158/1078-0432.22461303.v1
https://doi.org/10.1158/1078-0432.22461303.v1
Autor:
Jean-Charles Soria, Valerie Meresse, Ernesto Guarin, Michel Paques, Wilfried Ernst Erich Eberhardt, Jean J.L. Tessier, Françoise Kraeber-Bodéré, Miro Venturi, Simon Pacey, James Larkin, Luiz Paz-Ares, Emiliano Calvo, Mark R. Middleton, Jean-Philippe Spano, Jan H.M. Schellens, Veronique Dieras, Maria Martinez-Garcia, Fabrice Barlesi, Lisa Zimmer
Supplementary Figure 2. Case study: 64-year old female with BRAF V600-mutant melanoma (A) Immunhistochemistry for Ki67 expression showing a reduction between baseline and cycle1/day15 in lymph node biopsies (B) Immunhistochemistry for pERK expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56ff4910b9f44e59d235436e4fd36c4
https://doi.org/10.1158/1078-0432.22454862.v1
https://doi.org/10.1158/1078-0432.22454862.v1
Autor:
Michael Cannarile, Valeria Runza, Stefan Weigand, Valerie Meresse, Andrew L. Coveler, Devalingam Mahalingam, Carla van Herpen, Jean-Pierre Delord, Christophe Le Tourneau, Henk Verheul, Sabine Lohmann, Florian Heil, Konrad Honold, Adam Nopora, Edgar Voss, Fabian Birzele
Supplementary Tables 3, 5, 6 and 7. Supplementary Table 3: Contains the results of the differential gene expression analysis between CD44s HEK and native HEK cells (log ratios on the gene level and FDR corrected p-values) Supplementary Table 5: Conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b593e404f13a9e85d2d7dcab2575f9e
https://doi.org/10.1158/1078-0432.22461300
https://doi.org/10.1158/1078-0432.22461300
Autor:
Jean-Charles Soria, Valerie Meresse Naegelen, Steve Blotner, Eliezer Shochat, Jean J. L. Tessier, Ruediger Rueger, Zhi-Xin Xu, Ernesto Guarin, Emilie Routier, Federico Rojo, Françoise Kraeber-Bodéré, Saoirse Dolly, Rastilav Bahleda, Joan Albanell, Udai Banerji, Maria Martinez-Garcia
PDF file, 18K, Schematic showing cohort doses evaluated, dose-limiting-toxicities observed and maximum-tolerated-doses per dosing regimen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59472046794d1c2b3578f6cc4e14ad1
https://doi.org/10.1158/1078-0432.22451108.v1
https://doi.org/10.1158/1078-0432.22451108.v1