Výsledky vyhledávání - "Valeria Pozzato"

Ovalbumin sensitization of guinea pig at birth prevents the ontogenetic decrease in airway smooth muscle responsiveness

Autor: Delbert R. Dorscheid, Thomas M. Murphy, Charles L. Worthington, Simone Degan, Syed H. Hussaini, Wesley C. Turner, Valeria Pozzato, Lu Wang, Pasquale Chitano

Publikováno v: Physiological Reports

Airway smooth muscle (ASM) displays a hyperresponsive phenotype at young age and becomes less responsive in adulthood. We hypothesized that allergic sensitization, which causes ASM hyperresponsiveness and typically occurs early in life, prevents the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb5b063f03602c47987c8201a805bc3
https://pubmed.ncbi.nlm.nih.gov/25501429

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Reduced spontaneus relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release

Autor: Pasquale Chitano, Lu Wang, Valeria Pozzato, Graziella Turato, Thomas M. Murphy, Aasakiran Madamanchi

Airway smooth muscle (ASM) from infant guinea pigs has less spontaneous relaxation during stimulation than ASM from adults. Inhibition of cyclooxygenase (COX), which catalyzes the production of prostanoids, increases this relaxation in infant ASM and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a96384518b5c3516b38531557715d6
http://hdl.handle.net/11577/2270225

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Ontogenesis of myosin light chain kinase mRNA and protein content in guinea pig tracheal smooth muscle

Autor: Viviana Cantillana, Lu Wang, Pasquale Chitano, Thomas M. Murphy, Judith A. Voynow, Lauranell H. Burch, Valeria Pozzato

Publikováno v: Pediatric pulmonology. 38(6)

We previously reported in guinea pig tracheal smooth muscle that maximal shortening velocity decreases from 3 weeks of age to adulthood. It is not known whether myosin light chain kinase (MLCK), a key enzyme determining the velocity of smooth muscle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f21b124087f0eb50d6ff91f783c85a
https://pubmed.ncbi.nlm.nih.gov/15376333

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Long-term follow-up of toluene diisocyanate-induced asthma

Autor: Piero Maestrelli, L Zedda, G Milan, C. Piola, M Simoni, Ilaria Bononi, Valeria Pozzato, Piera Boschetto, Michele Padoan, Cristina E. Mapp

Eighty-seven cases of occupational asthma induced by toluene diisocyanate (TDI) were diagnosed by an inhalation challenge with TDI and methacholine. After an average follow-up interval of 11 yrs, all subjects were re-examined. Of the 87 subjects exam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec94ef299f2eb8233de1a67426d65f32
http://hdl.handle.net/11577/1357117

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Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates

Autor: Richard C. Strange, Monica A. Spiteri, Nicoletta De Marzo, Michele Padoan, Cristina E. Mapp, Anja Hemmingsen, Valeria Pozzato, Anthony A. Fryer, Piera Boschetto

Publikováno v: The Journal of allergy and clinical immunology. 109(5)

Background: Polymorphism at the π class glutathione-S-transferase locus (GSTP1) is associated with allergen-induced asthma and related phenotypes. Objective : We sought to determine whether GSTP1 polymorphism influences susceptibility to asthma indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54f3ac6b8d4fe7c78c0676bb3fe6c1b
https://pubmed.ncbi.nlm.nih.gov/11994698

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