Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Valeria Palumbo"'
Autor:
Pietro Poggio, Stefania Rocca, Federica Fusella, Roberta Ferretti, Ugo Ala, Flora D’Anna, Emilia Giugliano, Cristina Panuzzo, Diletta Fontana, Valeria Palumbo, Giovanna Carrà, Daniela Taverna, Carlo Gambacorti-Passerini, Giuseppe Saglio, Carmen Fava, Rocco Piazza, Alessandro Morotti, Francesca Orso, Mara Brancaccio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Morgana is a ubiquitous HSP90 co-chaperone protein coded by the CHORDC1 gene. Morgana heterozygous mice develop with age a myeloid malignancy resembling human atypical myeloid leukemia (aCML), now renamed MDS/MPN with neutrophilia. Patients
Externí odkaz:
https://doaj.org/article/6c827363c8c04882b2a5e5aa1fda4491
Autor:
Manuel Scimeca, Valeria Palumbo, Erica Giacobbi, Francesca Servadei, Stefano Casciardi, Elena Cornella, Federica Cerbara, Gabriele Rotondaro, Christian Seghetti, Maria Paola Scioli, Manuela Montanaro, Francesco Barillà, Renata Sisto, Gerry Melino, Alessandro Mauriello, Rita Bonfiglio
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38047- (2024)
Environmental pollution poses a significant threat to human health, particularly concerning its impact on cardiovascular diseases (CVDs). This review synthesizes epidemiological and molecular evidence to elucidate the intricate relationship between e
Externí odkaz:
https://doaj.org/article/efd6ef3698914f42a21ad0ebf742ce6c
Autor:
Elena Fiorelli, Maria Giovanna Scioli, Sonia Terriaca, Arsalan Ul Haq, Gabriele Storti, Marta Madaghiele, Valeria Palumbo, Ermal Pashaj, Fabio De Matteis, Diego Ribuffo, Valerio Cervelli, Augusto Orlandi
Publikováno v:
Bioengineering, Vol 11, Iss 9, p 920 (2024)
Osteochondral lesions may be due to trauma or congenital conditions. In both cases, therapy is limited because of the difficulty of tissue repair. Tissue engineering is a promising approach that relies on designed scaffolds with variable mechanical a
Externí odkaz:
https://doaj.org/article/de914d4e6bde423981707613ae7d8367
Autor:
Manuel Scimeca, Valentina Rovella, Valeria Palumbo, Maria Paola Scioli, Rita Bonfiglio, TOR CENTRE, Gerry Melino, Mauro Piacentini, Luigi Frati, Massimiliano Agostini, Eleonora Candi, Alessandro Mauriello
Publikováno v:
Cancers, Vol 15, Iss 14, p 3638 (2023)
Cholangiocarcinoma is a highly aggressive cancer arising from the bile ducts. The limited effectiveness of conventional therapies has prompted the search for new approaches to target this disease. Recent evidence suggests that distinct programmed cel
Externí odkaz:
https://doaj.org/article/9f954ac9671b4ef1ab7bb36f01492153
Autor:
Alyona V. Razuvaeva, Lucia Graziadio, Valeria Palumbo, Gera A. Pavlova, Julia V. Popova, Alexey V. Pindyurin, Silvia Bonaccorsi, Maria Patrizia Somma, Maurizio Gatti
Publikováno v:
Cells, Vol 12, Iss 6, p 922 (2023)
The Drosophila abnormal spindle (asp) gene was discovered about 40 years ago and shown to be required for both mitotic and meiotic cell division. Subsequent studies showed that asp is highly conserved and that mutations in its human ortholog ASPM (Ab
Externí odkaz:
https://doaj.org/article/b292e45b999142e0be2b9736be985ba5
Autor:
Nicola Antonio Martino, Ernesto Picardi, Elena Ciani, Anna Maria D’Erchia, Luisa Bogliolo, Federica Ariu, Antonella Mastrorocco, Letizia Temerario, Luigi Mansi, Valeria Palumbo, Graziano Pesole, Maria Elena Dell’Aquila
Publikováno v:
Biology, Vol 12, Iss 2, p 249 (2023)
Cadmium (Cd), a highly toxic pollutant, impairs oocyte fertilization, through oxidative damage on cumulus cells (CCs). This study analysed the transcriptomic profile of CCs of cumulus-oocyte complexes (COCs) from adult and prepubertal sheep, exposed
Externí odkaz:
https://doaj.org/article/924c1a4d974045ffb9835dbaa97af931
Autor:
Anna De Grassi, Patrizia Tritto, Valeria Palumbo, Maria Pia Bozzetti, Maria Francesca Berloco
Publikováno v:
Cells, Vol 11, Iss 23, p 3725 (2022)
The cry-Ste system is a genetic interaction system between heterochromatin and euchromatin in Drosophila melanogaster, regulated via the piRNA pathway. Deregulation of this system leads to meiotic defects and male sterility. Although the cry-Ste syst
Externí odkaz:
https://doaj.org/article/1b68d8be7bbd4422b760d51f35ab2586
Autor:
Paolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Veronica Lisi, Valeria Palumbo, Simone D'Angeli, Stefano Cacchione, Giovanni Cenci, Laura Ciapponi, James G Wakefield, Maurizio Gatti, Grazia Daniela Raffa
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008815 (2020)
Trimethylguanosine synthase 1 (TGS1) is a conserved enzyme that mediates formation of the trimethylguanosine cap on several RNAs, including snRNAs and telomerase RNA. Previous studies have shown that TGS1 binds the Survival Motor Neuron (SMN) protein
Externí odkaz:
https://doaj.org/article/6068dac10ba64033b50cebbe66a307f8
Autor:
Patrizia Tritto, Valeria Palumbo, Lucia Micale, Marco Marzulli, Maria Pia Bozzetti, Valeria Specchia, Gioacchino Palumbo, Sergio Pimpinelli, Maria Berloco
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120859 (2015)
Pol32 is an accessory subunit of the replicative DNA Polymerase δ and of the translesion Polymerase ζ. Pol32 is involved in DNA replication, recombination and repair. Pol32's participation in high- and low-fidelity processes, together with the phen
Externí odkaz:
https://doaj.org/article/8595c0f520804d3db357146d435ed7af
Autor:
Lu Chen, Caitlin M Roake, Paolo Maccallini, Francesca Bavasso, Roozbeh Dehghannasiri, Pamela Santonicola, Natalia Mendoza-Ferreira, Livia Scatolini, Ludovico Rizzuti, Alessandro Esposito, Ivan Gallotta, Sofia Francia, Stefano Cacchione, Alessandra Galati, Valeria Palumbo, Marie A Kobin, Gian Gaetano Tartaglia, Alessio Colantoni, Gabriele Proietti, Yunming Wu, Matthias Hammerschmidt, Cristiano De Pittà, Gabriele Sales, Julia Salzman, Livio Pellizzoni, Brunhilde Wirth, Elia Di Schiavi, Maurizio Gatti, Steven E Artandi, Grazia D Raffa
Publikováno v:
Nucleic Acids Research. 50:12400-12424
Trimethylguanosine synthase 1 (TGS1) is a highly conserved enzyme that converts the 5′-monomethylguanosine cap of small nuclear RNAs (snRNAs) to a trimethylguanosine cap. Here, we show that loss of TGS1 in Caenorhabditis elegans, Drosophila melanog