Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Valeria Nele"'
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background In non-small cell lung cancer (NSCLC) the efficacy of chemo-immunotherapy is affected by the high expression of drug efflux transporters as ABCC1 and by the low expression of ABCA1, mediating the isopentenyl pyrophosphate (IPP)-de
Externí odkaz:
https://doaj.org/article/4a6851a8a8824044acb7cc89ddb408bf
Autor:
Muhlis Akman, Ciro Monteleone, Gabriella Doronzo, Martina Godel, Francesca Napoli, Alessandra Merlini, Virginia Campani, Valeria Nele, Elisa Balmas, Tatiana Chontorotzea, Simona Fontana, Sabrina Digiovanni, Francesca Alice Barbu, Elena Astanina, Niloufar Jafari, Iris Chiara Salaroglio, Joanna Kopecka, Giuseppe De Rosa, Thomas Mohr, Alessandro Bertero, Luisella Righi, Silvia Novello, Giorgio Vittorio Scagliotti, Federico Bussolino, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/695ef33a539a4a9296cf6230050b6b60
Autor:
Pasquale Cepparulo, Ornella Cuomo, Virginia Campani, Antonio Vinciguerra, Maria Josè Sisalli, Valeria Nele, Serenella Anzilotti, Valeria Valsecchi, Antonella Casamassa, Paola Brancaccio, Antonella Scorziello, Giuseppe De Rosa, Lucio Annunziato, Giuseppe Pignataro
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102131- (2024)
MicroRNA (miRNA), by post-transcriptionally regulating the expression of genes involved in stroke response, represents important effectors in stroke pathophysiology. Recently, the 103/107 miRNA family emerged as a possible therapeutic target in strok
Externí odkaz:
https://doaj.org/article/2ebf7d8566f04d7f9aad9303fb3be282
Autor:
Marianna Abate, Angela Lombardi, Amalia Luce, Manuela Porru, Carlo Leonetti, Marco Bocchetti, Virginia Campani, Giuseppe De Rosa, Sossio Fabio Graziano, Valeria Nele, Francesco Cardile, Federica Zito Marino, Renato Franco, Andrea Ronchi, Marianna Scrima, Rossella Sperlongano, Roberto Alfano, Gabriella Misso, Evzen Amler, Michele Caraglia, Silvia Zappavigna
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 127-141 (2023)
Nanodiamonds are innovative nanocrystalline carbon particles able to deliver chemically conjugated miRNAs. In oncology, the use of miRNA-based therapies may represent an advantage, based on their ability to simultaneously target multiple intracellula
Externí odkaz:
https://doaj.org/article/c25edbbf2a774f64bb6dcb2905b5ccfc
Autor:
Fabrizio Villapiano, Ritamaria Di Lorenzo, Rosa Sparaco, Elisa Magli, Francesco Frecentese, Sonia Laneri, Alessandra D’Orsi, Valeria Nele, Marco Biondi, Laura Mayol, Virginia Campani, Vincenzo Santagada, Giuseppe De Rosa
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 777 (2024)
Chronic wounds are marked by an extended healing period during which damaged tissues fail to undergo orderly and timely repair. Examples of chronic wounds encompass venous ulcers, pressure ulcers, and diabetic foot ulcers. The process of wound healin
Externí odkaz:
https://doaj.org/article/5e54e6a42b0f47028cbed75bebae7b29
Autor:
Rossella Delle Donne, Rosa Iannucci, Laura Rinaldi, Luca Roberto, Maria A. Oliva, Emanuela Senatore, Domenica Borzacchiello, Luca Lignitto, Giorgio Giurato, Francesca Rizzo, Assunta Sellitto, Francesco Chiuso, Salvatore Castaldo, Giovanni Scala, Virginia Campani, Valeria Nele, Giuseppe De Rosa, Chiara D’Ambrosio, Corrado Garbi, Andrea Scaloni, Alessandro Weisz, Concetta Ambrosino, Antonella Arcella, Antonio Feliciello
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The E3 ubiquitin ligase praja2 is expressed in glioblastoma (GBM), targets the kinase suppressor of Ras 2 for degradation and attenuates oxidative metabolism. Nanoparticle-mediated delivery of praja2 siRNA to GBM-bearing mice reduces tumour size.
Externí odkaz:
https://doaj.org/article/f36755ba0d994459bddc465aebef1c4a
Autor:
Valeria Nele, Valentina Tedeschi, Virginia Campani, Raffaella Ciancio, Alessia Angelillo, Sossio Fabio Graziano, Giuseppe De Rosa, Agnese Secondo
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 358 (2023)
Neurodegenerative diseases are characterized by mitochondrial dysfunction leading to abnormal levels of reactive oxygen species (ROS), making the use of ROS-scavenging nanomaterials a promising therapeutic approach. Here, we combined the unique ROS-s
Externí odkaz:
https://doaj.org/article/7cb8f13edcea4a18ba1a44ceea16ab99
Autor:
Marianna Abate, Lorena Scotti, Valeria Nele, Michele Caraglia, Marco Biondi, Giuseppe De Rosa, Carlo Leonetti, Virginia Campani, Silvia Zappavigna, Manuela Porru
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5138 (2022)
Self-assembling nanoparticles (SANPs) promise an effective delivery of bisphosphonates or microRNAs in the treatment of glioblastoma (GBM) and are obtained through the sequential mixing of four components immediately before use. The self-assembling a
Externí odkaz:
https://doaj.org/article/3dcd70f2a89041bdbd492b0acc4850a5
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non-EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact
Externí odkaz:
https://doaj.org/article/0bbdcb14137e4af2829830fdd4deaadc
Targeted Self-Emulsifying Drug Delivery Systems to Restore Docetaxel Sensitivity in Resistant Tumors
Autor:
Virginia Campani, Iris Chiara Salaroglio, Valeria Nele, Joanna Kopecka, Andreas Bernkop-Schnürch, Chiara Riganti, Giuseppe De Rosa
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 292 (2022)
The use of chemotherapeutic agents such as docetaxel (DTX) in anticancer therapy is often correlated to side effects and the occurrence of drug resistance, which substantially impair the efficacy of the drug. Here, we demonstrate that self-emulsifyin
Externí odkaz:
https://doaj.org/article/b05a6b68b8d442d8aa326c81eb38b610