Výsledky vyhledávání - "Valeria Montani"

Transforming Growth Factor-β1 Down-Regulation of Major Histocompatibility Complex Class I in Thyrocytes: Coordinate Regulation Of Two Separate Elements by Thyroid-Specific as Well as Ubiquitous Transcription Factors

Autor: Minoru Nakazato, Giovanna Laglia, Valentina Todisco, Valeria Montani, F. Monaco, Giulia Colletta, Giorgio Napolitano, Simonetta Di Vincenzo, Leonard D. Kohn, Dinah S. Singer, Anna Coppa, Ines Bucci, Cesidio Giuliani

Publikováno v: Molecular Endocrinology. 14:486-505

Transforming growth factor (TGF)-beta1-decreased major histocompatibility complex (MHC) class I gene expression in thyrocytes is transcriptional; it involves trans factors and cis elements important for hormone- as well as iodide-regulated thyroid gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8849ab61f508be00e17ed77ab4637dd4
https://doi.org/10.1210/mend.14.4.0454

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Regulation of Major Histocompatibility (MHC) Class II Human Leukocyte Antigen-DRα Gene Expression in Thyrocytes by Single Strand Binding Protein-1, a Transcription Factor That Also Regulates Thyrotropin Receptor and MHC Class I Gene Expression

Autor: Giorgio Napolitano, Pina L. Balducci-Silano, Valeria Montani, Jun Saito, Stefano Lavaroni, Masanori Ohta, Dinah S. Singer, Masayuki Ohmori, Leonard D. Kohn, Shin-ichi Taniguchi, Koichi Suzuki, Michele Pietrarelli, Minho Shong, Atsumi Mori

Publikováno v: Endocrinology. 139:2300-2313

The single strand binding protein (SSBP-1) is a positive regulator of TSH receptor gene expression and binds to an element with a GXXXXG motif. The S box of the mouse major histocompatibility class II gene has multiple GXXXXG motifs and can also bind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d8e9a1096395fbf2dd9e6fe1a7a053
https://doi.org/10.1210/endo.139.5.5991

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Regulation of Major Histocompatibility Class II Gene Expression in FRTL-5 Thyrocytes: Opposite Effects of Interferon and Methimazole*

Autor: Koichi Suzuki, Dinah S. Singer, Bruno Fiorentino, Cesidio Giuliani, Minho Shong, Andreas M. Reimold, Motoyasu Saji, Valeria Montani, Shin-ichi Taniguchi, Giorgio Napolitano, Leonard D. Kohn, Jun Saito

Publikováno v: Endocrinology. 139:290-302

Aberrant expression of major histocompatibility complex (MHC) class II antigens is associated with autoimmune thyroid disease; aberrant expression duplicating the autoimmune state can be induced by interferon-gamma (IFNgamma). We have studied IFNgamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e21948233148f5748620c7d17134925
https://doi.org/10.1210/endo.139.1.5658

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Major Histocompatibility Class II HLA-DRα Gene Expression in Thyrocytes: Counter Regulation by the Class II Transactivator and the Thyroid Y Box Protein

Autor: Cesidio Giuliani, Giorgio Napolitano, Valeria Montani, Andreas M. Reimold, Minho Shong, Jenny P.-Y. Ting, Bruno Fiorentino, Motoyasu Saji, Shin-ichi Taniguchi, Dinah S. Singer, Leonard D. Kohn, Masayuki Ohmori, Koichi Suzuki

Publikováno v: Endocrinology. 139:280-289

Aberrant expression of major histocompatibility complex (MHC) class II proteins on thyrocytes, which is associated with autoimmune thyroid disease, is mimicked by gamma-interferon (gamma-IFN). To define elements and factors that regulate class II gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326ff4d6f3a95debdee046aaca449321
https://doi.org/10.1210/endo.139.1.5673

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Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole

Autor: Giorgio Napolitano, Valeria Montani, Ines Bucci, Cesidio Giuliani, Dinah S. Singer, F. Monaco, Leonard D. Kohn

Publikováno v: The Journal of endocrinology. 204(1)

Increased expression of major histocompatibility complex (MHC) class-I genes and aberrant expression of MHC class-II genes in thyroid epithelial cells (TECs) are associated with autoimmune thyroid diseases. Previous studies have shown that methimazol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e59eed1eaf4afecc7bea9cb3cf8870
https://pubmed.ncbi.nlm.nih.gov/19837722

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Iodide suppression of major histocompatibility class I gene expression in thyroid cells involves enhancer A and the transcription factor NF-kappa B

Autor: Minho Shong, Valeria Montani, Motoyasu Saji, Dinah S. Singer, Koichi Suzuki, Giorgio Napolitano, Leonard D. Kohn, Shin-ichi Taniguchi, Cesidio Giuliani

Publikováno v: Molecular endocrinology (Baltimore, Md.). 12(1)

High concentrations of iodide can induce transient, clinical improvement in patients with autoimmune Graves' disease. Previous work has related this iodide action to the autoregulatory effect of iodide on the growth and function of the thyroid; more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2b5cd5e6ff1a8d8c8c8302627e8817
https://pubmed.ncbi.nlm.nih.gov/9440807

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