Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valeria Guidolin"'
Autor:
Valeria Guidolin, Yupeng Li, Foster C. Jacobs, Margaret L. MacMillan, Peter W. Villalta, Stephen S. Hecht, Silvia Balbo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 197-210 (2023)
DNA alkylating drugs have been used as cancer chemotherapy with variable outcomes. The establishment of predictive biomarkers to identify patients who will effectively respond to treatment would allow for the development of personalized therapies. As
Externí odkaz:
https://doaj.org/article/f315c051a02546108a41e33146bf52da
Targeted High Resolution LC/MS3 Adductomics Method for the Characterization of Endogenous DNA Damage
Autor:
Andrea Carrà, Valeria Guidolin, Romel P. Dator, Pramod Upadhyaya, Fekadu Kassie, Peter W. Villalta, Silvia Balbo
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
DNA can be damaged through covalent modifications of the nucleobases by endogenous processes. These modifications, commonly referred to as DNA adducts, can persist and may lead to mutations, and ultimately to the initiation of cancer. A screening met
Externí odkaz:
https://doaj.org/article/687422b4c5214f029764927604d986e5
Autor:
Valeria Guidolin, Erik S. Carlson, Andrea Carrà, Peter W. Villalta, Laura A. Maertens, Stephen S. Hecht, Silvia Balbo
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 366 (2021)
Alcohol consumption is a risk factor for the development of several cancers, including those of the head and neck and the esophagus. The underlying mechanisms of alcohol-induced carcinogenesis remain unclear; however, at these sites, alcohol-derived
Externí odkaz:
https://doaj.org/article/6c70f60122434510be7df14aeaea875a
Autor:
Andrew M. Gulick, Courtney C. Aldrich, Eric J. Drake, Valeria Guidolin, Evan M. Alexander, Dale F. Kreitler, Alexander K. Hurben, Silvia Balbo, Peter W. Villalta
Publikováno v:
ACS Infect Dis
Tilimycin is an enterotoxin produced by the opportunistic pathogen Klebsiella oxytoca that causes antibiotic-associated hemorrhagic colitis (AAHC). This pyrrolobenzodiazepine (PBD) natural product is synthesized by a bimodular nonribosomal peptide sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617291f024e10a726790b85acbc53bc6
https://doi.org/10.1021/acsinfecdis.0c00326
https://doi.org/10.1021/acsinfecdis.0c00326
Autor:
Andrea Carrà, Z. Vivian Feng, Robert J. Hamers, Valeria Guidolin, Tian A. Qiu, Silvia Balbo, Peter W. Villalta, Thomas Pho, Jiayi He, Xiaoxiao Yao, Christy L. Haynes, Khoi Nguyen L. Hoang
Publikováno v:
Chemical Science
The increasing use of nanoscale lithium nickel manganese cobalt oxide (LixNiyMnzCo1−y−zO2, NMC) as a cathode material in lithium-ion batteries poses risk to the environment. Learning toxicity mechanisms on molecular levels is critical to promote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabff3c21fe4f823378db59479542a8e
https://pubmed.ncbi.nlm.nih.gov/34094365
https://pubmed.ncbi.nlm.nih.gov/34094365
Autor:
Valeria Guidolin, Jing Yang, Viviana Paiano, Silvia Balbo, Stephen S. Hecht, Laura A. Maertens
Publikováno v:
Chem Res Toxicol
Cigarette smoking is an important source of human exposure to toxicants and carcinogens and contributes significantly to cancer morbidity and mortality worldwide. Acrolein, a widespread environmental pollutant, is present in relatively high amounts i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e2c575401ba76626bb32e292b17ea7
https://europepmc.org/articles/PMC8185904/
https://europepmc.org/articles/PMC8185904/
Targeted High Resolution LC/MS3 Adductomics Method for the Characterization of Endogenous DNA Damage
Autor:
Valeria Guidolin, Peter W. Villalta, Pramod Upadhyaya, Silvia Balbo, Andrea Carrà, Fekadu Kassie, Romel P Dator
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry, Vol 7 (2019)
DNA can be damaged through covalent modifications of the nucleobases by endogenous processes. These modifications, commonly referred to as DNA adducts, can persist and may lead to mutations, and ultimately to the initiation of cancer. A screening met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570a44cd77a09d2cea0a6cda2e1f08b3
http://europepmc.org/articles/PMC6822301
http://europepmc.org/articles/PMC6822301
Autor:
Peter W. Villalta, Silvia Balbo, Valeria Guidolin, Erik S. Carlson, Andrea Carrà, Stephen S. Hecht, Laura A. Maertens
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 366, p 366 (2021)
Volume 11
Issue 3
Biomolecules, Vol 11, Iss 366, p 366 (2021)
Volume 11
Issue 3
Alcohol consumption is a risk factor for the development of several cancers, including those of the head and neck and the esophagus. The underlying mechanisms of alcohol-induced carcinogenesis remain unclear
however, at these sites, alcohol-deri
however, at these sites, alcohol-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f9c3ad37bbd458831fcaf9ba1e233a
https://doi.org/10.3390/biom11030366
https://doi.org/10.3390/biom11030366
Publikováno v:
Cancers, Vol 10, Iss 3, p 74 (2018)
Cancers
Cancers
Alcohol is classified by the International Agency for Research on Cancer (IARC) as a human carcinogen and its consumption has been associated to an increased risk of liver, breast, colorectum, and upper aerodigestive tract (UADT) cancers. Its mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91236956ae707271192200a84b635d24
http://www.mdpi.com/2072-6694/10/3/74
http://www.mdpi.com/2072-6694/10/3/74
Publikováno v:
Cancers, Vol 10, Iss 1, p 20 (2018)
Alcohol is classified by the International Agency for Research on Cancer (IARC) as a human carcinogen and its consumption has been associated to an increased risk of liver, breast, colorectum, and upper aerodigestive tract (UADT) cancers. Its mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c37c62bf72e0b21c1d96228b1da817b
http://www.mdpi.com/2072-6694/10/1/20
http://www.mdpi.com/2072-6694/10/1/20