Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Valeria Eckhardt"'
Autor:
Marco Bardelli, Karl Frontzek, Luca Simonelli, Simone Hornemann, Mattia Pedotti, Federica Mazzola, Manfredi Carta, Valeria Eckhardt, Rocco D'Antuono, Tommaso Virgilio, Santiago F González, Adriano Aguzzi, Luca Varani
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007335 (2018)
Antibodies to the prion protein, PrP, represent a promising therapeutic approach against prion diseases but the neurotoxicity of certain anti-PrP antibodies has caused concern. Here we describe scPOM-bi, a bispecific antibody designed to function as
Externí odkaz:
https://doaj.org/article/b333e425dac04363bafbe5d00b152b89
Autor:
Valeria Eckhardt, Claudia Scheckel, Marc Emmenegger, Daniel Patrick Pease, Ioannis Xenarios, Elke Schaper, Adriano Aguzzi
Publikováno v:
Brain Pathology. 29:232-244
The cellular prion protein (PrPC ) is best known for its misfolded disease-causing conformer, PrPS c . Because the availability of PrPC is often limiting for prion propagation, understanding its regulation may point to possible therapeutic targets. W
Autor:
Federica Mazzola, Valeria Eckhardt, Rocco D'Antuono, Manfredi Carta, Marco Bardelli, Simone Hornemann, Mattia Pedotti, Luca Simonelli, Adriano Aguzzi, Tommaso Virgilio, Luca Varani, Karl Frontzek, Santiago F. Gonzalez
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 10, p e1007335 (2018)
PLoS Pathogens, Vol 14, Iss 10, p e1007335 (2018)
Antibodies to the prion protein, PrP, represent a promising therapeutic approach against prion diseases but the neurotoxicity of certain anti-PrP antibodies has caused concern. Here we describe scPOM-bi, a bispecific antibody designed to function as
Autor:
Daniel, Pease, Claudia, Scheckel, Elke, Schaper, Valeria, Eckhardt, Marc, Emmenegger, Ioannis, Xenarios, Adriano, Aguzzi
Publikováno v:
Brain Pathol
The cellular prion protein (PrP(C)) is best known for its misfolded disease‐causing conformer, PrP(Sc). Because the availability of PrP(C) is often limiting for prion propagation, understanding its regulation may point to possible therapeutic targe