Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valeria C. Labra"'
Autor:
Gonzalo I. Gómez, Romina V. Falcon, Carola J. Maturana, Valeria C. Labra, Nicole Salgado, Consuelo A. Rojas, Juan E. Oyarzun, Waldo Cerpa, Rodrigo A. Quintanilla, Juan A. Orellana
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
A mounting body of evidence indicates that adolescents are specially more susceptible to alcohol influence than adults. However, the mechanisms underlying this phenomenon remain poorly understood. Astrocyte-mediated gliotransmission is crucial for hi
Externí odkaz:
https://doaj.org/article/4300ac1bc8854dfabe1467bfed1d39c1
Autor:
Rosario Gajardo-Gómez, Cristian A. Santibañez, Valeria C. Labra, Gonzalo I. Gómez, Eliseo A. Eugenin, Juan A. Orellana
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2503 (2020)
At least half of human immunodeficiency virus (HIV)-infected individuals suffer from a wide range of cognitive, behavioral and motor deficits, collectively known as HIV-associated neurocognitive disorders (HAND). The molecular mechanisms that amplify
Externí odkaz:
https://doaj.org/article/abe4dbe843374ec6857e3f30d54caf5d
Autor:
Juan C. Sáez, Susana Contreras-Duarte, Gonzalo I. Gómez, Valeria C. Labra, Cristian A. Santibañez, Rosario Gajardo-Gómez, Beatriz C. Avendaño, Esteban F. Díaz, Trinidad D. Montero, Victoria Velarde, Juan A. Orellana
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The present work was done to elucidate whether hemichannels of a cell line derived from endothelial cells are affected by pro-inflammatory conditions (high glucose and IL-1β/TNF-α) known to lead to vascular dysfunction. We used EAhy 926 cells treat
Externí odkaz:
https://doaj.org/article/1e4f03d8525a4bd293b2ee61e30ff826
Autor:
Valeria C. Labra, Cristian A. Santibáñez, Rosario Gajardo-Gómez, Esteban F. Díaz, Gonzalo I. Gómez, Juan A. Orellana
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
The formation of gap junctions was initially thought to be the central role of connexins, however, recent evidence had brought to light the high relevance of unopposed hemichannels as an independent mechanism for the selective release of biomolecules
Externí odkaz:
https://doaj.org/article/c952ded3708847a1b15c37fb0a9f7ba5
Autor:
Gonzalo Gomez, Eliseo A. Eugenin, Cristian A. Santibañez, Juan A. Orellana, Rosario Gajardo-Gómez, Valeria C. Labra
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 7
International Journal of Molecular Sciences, Vol 21, Iss 2503, p 2503 (2020)
Volume 21
Issue 7
International Journal of Molecular Sciences, Vol 21, Iss 2503, p 2503 (2020)
At least half of human immunodeficiency virus (HIV)-infected individuals suffer from a wide range of cognitive, behavioral and motor deficits, collectively known as HIV-associated neurocognitive disorders (HAND). The molecular mechanisms that amplify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d10bbd2d3bca8386790b00fb57e1f1d3
https://pubmed.ncbi.nlm.nih.gov/32260308
https://pubmed.ncbi.nlm.nih.gov/32260308
Autor:
Mauricio A. Retamal, Susana Contreras-Duarte, Juan C. Sáez, Juan A. Orellana, Cristian A. Santibañez, Victoria Velarde, Luis A. Mellado, Tanhia F. Alvear, Valeria C. Labra, Carla A. Inostroza
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1867(8)
Both IFN-γ or high glucose have been linked to systemic inflammatory imbalance with serious repercussions not only for endothelial function but also for the formation of the atherosclerotic plaque. Although the uncontrolled opening of connexin hemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cad4f270b5c65dcf804b2fc9ade5db6
https://pubmed.ncbi.nlm.nih.gov/32302669
https://pubmed.ncbi.nlm.nih.gov/32302669
Autor:
Esteban F. Díaz, Carla A. Inostroza, Luis A. Mellado, Rodrigo A. Quintanilla, Nicole Salgado, Valeria C. Labra, Juan Esteban Oyarzún, Juan A. Orellana, Tanhia F. Alvear
Publikováno v:
Glia.
Diverse studies have suggested that cytoplasmic inclusions of misfolded α-synuclein in neuronal and glial cells are main pathological features of different α-synucleinopathies, including Parkinson's disease and dementia with Lewy bodies. Up to now,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::628cf81759538d6357687bc349863c67
https://doi.org/10.1002/glia.23631
https://doi.org/10.1002/glia.23631
Autor:
Christian Giaume, Juan A. Orellana, Carola J. Maturana, Cristian A. Santibañez, Valeria C. Labra, Kenji F. Shoji, Juan C. Sáez, Rosario Gajardo-Gómez
Publikováno v:
Glia. 65:122-137
The mechanisms involved in Alzheimer's disease are not completely understood and how astrocytes and their gliotransmission contribute to this neurodegenerative disease remains to be fully elucidated. Previous studies have shown that amyloid-β peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::274a00d73f5e4187f54b289cc85dadf3
https://doi.org/10.1002/glia.23080
https://doi.org/10.1002/glia.23080
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Under physiological conditions, microglia adopt a resting phenotype associated with the production of anti-inflammatory and neurotrophic factors. In response to a wide variety of insults, these cells shift to an activated phenotype that is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9891c02225e4b8e3a80f6357d318b2
http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00086/full
http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00086/full
Autor:
Rosario, Gajardo-Gómez, Valeria C, Labra, Carola J, Maturana, Kenji F, Shoji, Cristian A, Santibañez, Juan C, Sáez, Christian, Giaume, Juan A, Orellana
Publikováno v:
Glia. 65(1)
The mechanisms involved in Alzheimer's disease are not completely understood and how astrocytes and their gliotransmission contribute to this neurodegenerative disease remains to be fully elucidated. Previous studies have shown that amyloid-β peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad9468e1fa2a6062723a5ed515be756c
https://pubmed.ncbi.nlm.nih.gov/27757991
https://pubmed.ncbi.nlm.nih.gov/27757991