Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Valeria Bianconi"'
Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca2+-Activated KCa3.1 Channels
Autor:
Marta Morotti, Stefano Garofalo, Germana Cocozza, Fabrizio Antonangeli, Valeria Bianconi, Chiara Mozzetta, Maria Egle De Stefano, Riccardo Capitani, Heike Wulff, Cristina Limatola, Myriam Catalano, Francesca Grassi
Publikováno v:
Life, Vol 12, Iss 4, p 538 (2022)
Duchenne muscular dystrophy (DMD) is an X-linked disease, caused by a mutant dystrophin gene, leading to muscle membrane instability, followed by muscle inflammation, infiltration of pro-inflammatory macrophages and fibrosis. The calcium-activated po
Externí odkaz:
https://doaj.org/article/c150d023676543ebae690e664575e39d
Autor:
Pietro Randazzo, Roberta Sinisi, Davide Gornati, Stefania Bertuolo, Leda Bencheva, Marilenia De Matteo, Martina Nibbio, Edith Monteagudo, Lorenzo Turcano, Valeria Bianconi, Giovanna Peruzzi, Vincenzo Summa, Alberto Bresciani, Chiara Mozzetta, Romano Di Fabio
Publikováno v:
Bioorganicmedicinal chemistry letters. 72
A new series of in vitro potent and highly selective histone methyl transferase enzyme G9a inhibitors was obtained. In particular, compound 2a, one the most potent G9a inhibitor identified, was endowed with >130-fold selectivity over GLP and excellen
Autor:
Chiara Mozzetta, VALERIA BIANCONI
Publikováno v:
Trends in genetics : TIG. 38(5)
Muscle stem cells (MuSCs) are responsible for skeletal muscle homeostasis and repair. In response to extracellular cues, MuSCs activate from quiescence, expand, differentiate into mature myofibers, and self-renew within their regenerative niche. Thes
Autor:
Tiziana Santini, Romano Di Fabio, Valeria Bianconi, Fabrizia Marullo, Giovanna Peruzzi, Daniel Fernandez Perez, Diego Pasini, Stefano Biagioni, Carlo Toniatti, Vincenzo Summa, Beatrice Biferali, Federica Polverino, Roberta Maggio, Sigmar Stricker, Chiara Mozzetta, Sophie Pöhle Kronawitter, Fulvio Chiacchiera
Publikováno v:
Science Advances
A druggable mechanism is found to reprogram fibro-adipogenic progenitors toward myogenesis and to improve muscle repair.
H3K9 methylation maintains cell identity orchestrating stable silencing and anchoring of alternate fate genes within the het
H3K9 methylation maintains cell identity orchestrating stable silencing and anchoring of alternate fate genes within the het
Autor:
Alberto Gualtieri, Valeria Bianconi, Alessandra Renzini, Luisa Pieroni, Valerio Licursi, Chiara Mozzetta
Publikováno v:
Cell reports. 40(9)
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood characterized by the inability to exit the proliferative myoblast-like stage. The alveolar fusion positive subtype (FP-RMS) is the most aggressive and is mainly caused by the
Publikováno v:
SSRN Electronic Journal.
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood characterized by the inability to exit the proliferative myoblast-like stage. The alveolar fusion positive subtype (FP-ARMS) is the most aggressive and is mainly caused by the