Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Valeria Benedusi"'
Autor:
Clara Meda, Valeria Benedusi, Alessandro Cherubini, Luca Valenti, Adriana Maggi, Sara Della Torre
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101143- (2024)
Background & Aims: The loss of ovarian functions defining menopause leads to profound metabolic changes and heightens the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD). Although estrogens primarily act on the fem
Externí odkaz:
https://doaj.org/article/1154a0a2003049acbe39dd3309c9da65
Autor:
Sara Della Torre, Valeria Benedusi, Giovanna Pepe, Clara Meda, Nicoletta Rizzi, Nina Henriette Uhlenhaut, Adriana Maggi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Menopause is associated with metabolic changes and an increased risk of a number of chronic diseases. Here, the authors show in a mouse model of menopause that an amino acid-enriched diet rescues liver lipid metabolism and prevents weight gain in a m
Externí odkaz:
https://doaj.org/article/aecd3a09aeab45749fa1ea641e6e0483
Autor:
Valeria Benedusi, Sara Della Torre, Nico Mitro, Donatella Caruso, Alessandra Oberto, Claire Tronel, Clara Meda, Adriana Maggi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Recent work revealed the major role played by liver Estrogen Receptor α (ERα) in the regulation of metabolic and reproductive functions. By using mutant mice with liver-specific ablation of Erα, we here demonstrate that the hepatic ERα i
Externí odkaz:
https://doaj.org/article/f63ae611519f4eff8bfd3828c8cb5cee
Autor:
Valeria Benedusi
Publikováno v:
Materials and Methods. 8
Autor:
N. Cesari, Nicoletta Rizzi, Adriana Maggi, Valeria Benedusi, Alessandro Villa, Electra Brunialti, Paolo Ciana
Publikováno v:
Journal of Neuroendocrinology
Most of the ageing-associated pathologies are coupled with a strong inflammatory component that accelerates the progress of the physiopathological functional decline related to ageing. The currently available pharmacological tools for the control of
Publikováno v:
Nature reviews. Endocrinology. 10(1)
In female animals, energy metabolism and fertility are tightly connected, and reciprocally regulated. However, the relative contributions of metabolic and reproductive pathways have changed over the course of evolution. In oviparous animals, metaboli
Publikováno v:
Journal of Biological Chemistry
The Journal of Biological Chemistry
Journal of Biological Chemistry; Vol 287
The Journal of Biological Chemistry
Journal of Biological Chemistry; Vol 287
Background: The mechanism of motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is poorly understood. Results: The peroxisome proliferator-activated receptor γ (PPARγ) can be activated by lipid peroxidation metabolites in ALS motor ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551ce1312ca6d8feb907f031c7be869
https://zenodo.org/record/7643
https://zenodo.org/record/7643
Autor:
Sara Della Torre, Clara Meda, Valeria Benedusi, Giuseppina Monteleone, Adriana Maggi, Elisabetta Vegeto
Publikováno v:
Endocrinology. 153(6)
Although several lines of evidence have indicated that menopause is associated with increased susceptibility to neurological disorders, the mechanisms involved in this phenomenon remain to be elucidated. Because neuroinflammation is a common feature
Recent studies highlight the prominent role played by estrogens in protecting the central nervous system (CNS) against the noxious consequences of a chronic inflammatory reaction. The neurodegenerative process of several CNS diseases, including Multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0899549a2b70a1869a20b0304593de64
https://europepmc.org/articles/PMC2630539/
https://europepmc.org/articles/PMC2630539/
Publikováno v:
Annals of the New York Academy of Sciences. 1089
The fertile period of women's life compared to menopause is associated with a lower incidence of degenerative inflammatory diseases. In brain, estrogens ameliorate brain performance and have positive effects on selected neural pathologies characteriz