Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Valeria Alberizzi,"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 7, Pp 840-847 (2013)
Glioblastoma (GBM) is a devastating brain tumor with a poor survival outcome. It is generated and propagated by a small subpopulation of rare and hierarchically organized cells that share stem-like features with normal stem cells but, however, appear
Externí odkaz:
https://doaj.org/article/77fd3ae30a244847acce5477571e59f4
Autor:
Alessandra Bolino, Françoise Piguet, Valeria Alberizzi, Marta Pellegatta, Cristina Rivellini, Marta Guerrero‐Valero, Roberta Noseda, Chiara Brombin, Alessandro Nonis, Patrizia D'Adamo, Carla Taveggia, Stefano Carlo Previtali
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 12, Pp 1438-1454 (2016)
Abstract Charcot–Marie–Tooth (CMT) neuropathies are highly heterogeneous disorders caused by mutations in more than 70 genes, with no available treatment. Thus, it is difficult to envisage a single suitable treatment for all pathogenetic mechanis
Externí odkaz:
https://doaj.org/article/c9084326117846fcb36a849fe5607d3a
Autor:
Roberta Noseda, Marta Guerrero-Valero, Valeria Alberizzi, Stefano C Previtali, Diane L Sherman, Marilena Palmisano, Richard L Huganir, Klaus-Armin Nave, Ana Cuenda, Maria Laura Feltri, Peter J Brophy, Alessandra Bolino
Publikováno v:
PLoS Biology, Vol 14, Iss 4, p e1002440 (2016)
Microtubule-based kinesin motors have many cellular functions, including the transport of a variety of cargos. However, unconventional roles have recently emerged, and kinesins have also been reported to act as scaffolding proteins and signaling mole
Externí odkaz:
https://doaj.org/article/0c85f8955fe04ce2ad1d8bafe0230402
Autor:
Davide Sala, Francesca Ornaghi, Francesco Morena, Chiara Argentati, Manuela Valsecchi, Valeria Alberizzi, Roberta Di Guardo, Alessandra Bolino, Massimo Aureli, Sabata Martino, Angela Gritti
The GM2 gangliosidoses Tay-Sachs disease and Sandhoff disease (SD) are respectively caused by mutations in the HEXA and HEXB genes encoding the α and β subunits of β-N-acetylhexosaminidase (Hex). The consequential accumulation of ganglioside in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36b1605c05632177871f88568ac7db9
https://hdl.handle.net/11391/1516214
https://hdl.handle.net/11391/1516214
Autor:
Gaëtan Chicanne, Francesca Bianchi, Linda Sawade, Ivan de Curtis, Ubaldo Del Carro, Yesim Parman, Marta Guerrero-Valero, Roberta Di Guardo, Davide Pareyson, Valeria Alberizzi, Bernard Payrastre, Federica Grandi, Silvia Cipriani, Angelo Schenone, Alessandra Bolino, Volker Haucke
Publikováno v:
Proc Natl Acad Sci U S A
Charcot-Marie-Tooth type 4B1 (CMT4B1) is a severe autosomal recessive demyelinating neuropathy with childhood onset, caused by loss-of-function mutations in the myotubularin-related 2 (MTMR2) gene. MTMR2 is a ubiquitously expressed catalytically acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdec724fd3719cb7bff8dddbaf9c0f2
http://hdl.handle.net/11567/1057661
http://hdl.handle.net/11567/1057661
Autor:
Roberta Noseda, Stefano C. Previtali, Chiara Brombin, Marta Pellegatta, Françoise Piguet, Valeria Alberizzi, Cristina Rivellini, Marta Guerrero-Valero, Alessandra Bolino, Carla Taveggia, Alessandro Nonis, Patrizia D'Adamo
Publikováno v:
EMBO Molecular Medicine
Charcot–Marie–Tooth (CMT) neuropathies are highly heterogeneous disorders caused by mutations in more than 70 genes, with no available treatment. Thus, it is difficult to envisage a single suitable treatment for all pathogenetic mechanisms. Axona
Autor:
Antonietta Carbone, Yevgeniya A. Mironova, Guy M. Lenk, Miriam H. Meisler, Alessandra Bolino, Roman J. Giger, Stefano C. Previtali, Ilaria Vaccari, Maurizio D'Antonio, Cristina Rivellini, Lawrence Wrabetz, Ubaldo Del Carro, Valeria Alberizzi, Francesca Bianchi, Roberta Noseda
Publikováno v:
Human Molecular Genetics
Mutations of FIG4 are responsible for Yunis-Varón syndrome, familial epilepsy with polymicrogyria, and Charcot-Marie-Tooth type 4J neuropathy (CMT4J). Although loss of the FIG4 phospholipid phosphatase consistently causes decreased PtdIns(3,5)P₂ l
Autor:
Stefano C. Previtali, Richard L. Huganir, Marilena Palmisano, Alessandra Bolino, Valeria Alberizzi, Peter J. Brophy, Klaus-Armin Nave, Ana Cuenda, Roberta Noseda, Diane L. Sherman, Marta Guerrero-Valero, Maria Laura Feltri
Publikováno v:
PLoS Biology
Noseda, R, Guerrero-Valero, M, Alberizzi, V, Previtali, S C, Sherman, D, Palmisano, M, Huganir, R L, Nave, K-A, Cuenda, A, Feltri, M L, Brophy, P & Bolino, A 2016, ' Kif13b Regulates PNS and CNS Myelination Through the Dlg1 Scaffold ', PLoS Biology, vol. 14, no. 4 . https://doi.org/10.1371/journal.pbio.1002440
PLoS Biology, Vol 14, Iss 4, p e1002440 (2016)
Noseda, R, Guerrero-Valero, M, Alberizzi, V, Previtali, S C, Sherman, D, Palmisano, M, Huganir, R L, Nave, K-A, Cuenda, A, Feltri, M L, Brophy, P & Bolino, A 2016, ' Kif13b Regulates PNS and CNS Myelination Through the Dlg1 Scaffold ', PLoS Biology, vol. 14, no. 4 . https://doi.org/10.1371/journal.pbio.1002440
PLoS Biology, Vol 14, Iss 4, p e1002440 (2016)
Microtubule-based kinesin motors have many cellular functions, including the transport of a variety of cargos. However, unconventional roles have recently emerged, and kinesins have also been reported to act as scaffolding proteins and signaling mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9a659265c84b017da4721441ddc12f
https://hdl.handle.net/11858/00-001M-0000-002C-1084-C11858/00-001M-0000-002C-1086-8
https://hdl.handle.net/11858/00-001M-0000-002C-1084-C11858/00-001M-0000-002C-1086-8
Autor:
Francesco Morena, Wilem Kulik, Ubaldo Del Carro, Alessandra Biffi, Silvia Ungari, Sabata Martino, Nicole Rufo, Angela Gritti, Alessandra Bolino, Valeria Alberizzi, Francesca Bianchi, Alessandra Ricca
Publikováno v:
Human Molecular Genetics
Human molecular genetics, 24(12), 3372-3389. Oxford University Press
Human molecular genetics, 24(12), 3372-3389. Oxford University Press
Globoid cell leukodystrophy (GLD) is a lysosomal storage disease caused by deficient activity of β-galactocerebrosidase (GALC). The infantile forms manifest with rapid and progressive central and peripheral demyelination, which represent a major hur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a3b2541bce7eb6f0e425a5d20fb61b
https://hdl.handle.net/11391/1367490
https://hdl.handle.net/11391/1367490
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 7, Pp 840-847 (2013)
Glioblastoma (GBM) is a devastating brain tumor with a poor survival outcome. It is generated and propagated by a small subpopulation of rare and hierarchically organized cells that share stem-like features with normal stem cells but, however, appear