Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Valeria, Pittalà"'
Autor:
Sebastiano Intagliata, Valeria Ciaffaglione, Valeria Consoli, Agata Grazia D'Amico, Luca Vanella, Valeria Pittalà, Federica Sodano, Marica Erminia Schiano, Valeria Sorrenti, Loredana Salerno
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100227- (2024)
Heme oxygenase-1 (HO-1) is involved in the oncogenesis of glioblastoma (GBM). In this work, we investigated for the first time how the co-administration (combo) of the HO-1 inhibitors SI1/09 or LS6/42 with temozolomide (TMZ) or temozolomide acid (TMZ
Externí odkaz:
https://doaj.org/article/8e09821e8da1442bbb50709288e645ac
Autor:
Loredana Salerno, Antonietta Notaro, Valeria Consoli, Federica Affranchi, Valeria Pittalà, Valeria Sorrenti, Luca Vanella, Michela Giuliano, Sebastiano Intagliata
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractColon cancer remains a clinical challenge in industrialised countries. Its treatment with 5-Flurouracil (5-FU) develops many side effects and resistance. Thus, several strategies have been undertaken so far, including the use of drug cocktail
Externí odkaz:
https://doaj.org/article/7cbdfd4d092d43a08cfd45bb07e543c4
Autor:
Nicola Filippo Virzì, Patricia Diaz-Rodriguez, Angel Concheiro, Valeria Pittalà, Carmen Alvarez-Lorenzo
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 7, Iss , Pp 100523- (2024)
Biodegradable and eco-sustainable medical devices represent an urgent need to face up to the increasing pollution associated to plastic device wastes. The present study aimed to develop semisolid extruded 3D (SSE-3D)-printed medical devices using mix
Externí odkaz:
https://doaj.org/article/5a1f54bd897342b58d3125fde14bfd78
Autor:
Irene Suárez-Rojas, Montse Pérez-Fernández, Xue Bai, Ignacio Martínez-Martel, Sebastiano Intagliata, Valeria Pittalà, Loredana Salerno, Olga Pol
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1859 (2023)
Neuropathic pain is a type of pain that persists for a long time and becomes pathological. Additionally, the anxiodepressive disorders derived from neuropathic pain are difficult to palliate with the current treatments and need to be resolved. Then,
Externí odkaz:
https://doaj.org/article/cdabdd8d52d54e6885020d46168e7069
Autor:
Montse Pérez-Fernández, Irene Suárez-Rojas, Xue Bai, Ignacio Martínez-Martel, Valeria Ciaffaglione, Valeria Pittalà, Loredana Salerno, Olga Pol
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1794 (2023)
Chronic pain caused by persistent inflammation is current in multiple diseases and has a strong negative impact on society. It is commonly associated with several mental illnesses, which can exert a negative influence on pain perception, and needs to
Externí odkaz:
https://doaj.org/article/e923ddf6868742af94fdf487923caca3
Autor:
Lucia Longhitano, Giuseppe Broggi, Sebastiano Giallongo, Maria Failla, Lidia Puzzo, Teresio Avitabile, Daniele Tibullo, Alfio Distefano, Valeria Pittalà, Michele Reibaldi, Guido Nicola Zanghì, Antonio Longo, Andrea Russo, Rosario Caltabiano, Giovanni Li Volti, Nicolò Musso
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1997 (2022)
Uveal melanoma (UM) is the most common primary intraocular tumor in adults. To date, the main strategies to counteract its progression consist of focal radiation on the tumor site and ocular enucleation. Furthermore, many UM patients develop liver me
Externí odkaz:
https://doaj.org/article/78f18d48548a4f99854897bd4a63ebd2
Autor:
Valeria Ciaffaglione, Valeria Consoli, Sebastiano Intagliata, Agostino Marrazzo, Giuseppe Romeo, Valeria Pittalà, Khaled Greish, Luca Vanella, Giuseppe Floresta, Antonio Rescifina, Loredana Salerno, Valeria Sorrenti
Publikováno v:
Molecules, Vol 27, Iss 10, p 3220 (2022)
This paper reports on a novel series of tyrosine kinase inhibitors (TKIs) potentially useful for the treatment of chronic myeloid leukemia (CML). The newly designed and synthesized compounds are structurally related to nilotinib (NIL), a second-gener
Externí odkaz:
https://doaj.org/article/04d5594b9bda4cd4bfd90b74c5595aec
Autor:
Giuseppe Floresta, Antonino Nicolò Fallica, Vincenzo Patamia, Valeria Sorrenti, Khaled Greish, Antonio Rescifina, Valeria Pittalà
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1289 (2021)
HO-1 overexpression has been reported in several cases/types of human malignancies. Unfortunately, poor clinical outcomes are reported in most of these cases, and the inhibition of HO-1 is considered a valuable and proven anticancer approach. To iden
Externí odkaz:
https://doaj.org/article/9f686c33e5db4976b0e05e4c948253c3
Publikováno v:
Antioxidants & Redox Signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34883eed1ce1e8bfd5c9dbd4c9c44181
https://doi.org/10.1089/ars.2022.0179
https://doi.org/10.1089/ars.2022.0179
Autor:
Agata Grazia D’Amico, Grazia Maugeri, Luca Vanella, Valeria Pittalà, Dora Reglodi, Velia D’Agata
Publikováno v:
Brain Sciences, Vol 11, Iss 8, p 994 (2021)
Glioblastoma multiforme (GBM) is the deadliest form of brain tumors. To date, the GBM therapeutical approach consists of surgery, radiation-therapy and chemotherapy combined with molecules improving cancer responsiveness to treatments. In this review
Externí odkaz:
https://doaj.org/article/c3c7afe628144b00b58ab053b84bc8c9