Linking In Vitro Models of Endothelial Dysfunction with Cell Senescence

Autor: Francisco R. Jimenez Trinidad, Marta Arrieta Ruiz, Núria Solanes Batlló, Àngela Vea Badenes, Joaquim Bobi Gibert, Antoni Valera Cañellas, Mercè Roqué Moreno, Xavier Freixa Rofastes, Manel Sabaté Tenas, Ana Paula Dantas, Olga Tura-Ceide, Montserrat Rigol Muxart

Publikováno v: Life, Vol 11, Iss 12, p 1323 (2021)

Endothelial cell dysfunction is the principal cause of several cardiovascular diseases that are increasing in prevalence, healthcare costs, and mortality. Developing a standardized, representative in vitro model of endothelial cell dysfunction is fun

Externí odkaz: https://doaj.org/article/715c5f43f7994c649b6ea40f63d7525e

Linking in vitro models of endothelial dysfunction with cell senescence

Autor: Àngela Vea Badenes, Manel Sabaté Tenas, Joaquim Bobi Gibert, Francisco R. Jimenez Trinidad, Ana Paula Dantas, Marta Arrieta Ruiz, Montserrat Rigol Muxart, Antoni Valera Cañellas, Mercè Roqué Moreno, Olga Tura-Ceide, Xavier Freixa Rofastes, Núria Solanes Batlló

Publikováno v: Life, 11(12):1323. Multidisciplinary Digital Publishing Institute (MDPI)
Life, Vol 11, Iss 1323, p 1323 (2021)
Life; Volume 11; Issue 12; Pages: 1323
Scientia
Life

Disfunció endotelial; Envellliment cel·lular Disfunción endotelial; Envejecimiento celular Endothelial dysfunction; Senescence Endothelial cell dysfunction is the principal cause of several cardiovascular diseases that are increasing in prevalence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87736eb6ee79f253625927dc1b0a84c0
https://pure.eur.nl/en/publications/298f975d-1871-4f67-b8db-5c78effe00d6

Opposite effects of moderate and extreme Cx43 deficiency in conditional Cx43-deficient mice on angiotensin II-induced cardiac fibrosis

Autor: Valls de Lacalle, Laura, Rodríguez, Cristina, Negre-Pujol, Corall, Varona, Saray, Antoni Valera Cañellas, Consegal, Marta, Martínez-González, Jose, Rodríguez-Sinovas, Antonio, Universitat Autònoma de Barcelona

Publikováno v: Scientia
Cells, Vol 8, Iss 10, p 1299 (2019)
Cells
Volume 8
Issue 10
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname

Connexin 43 (Cx43) is essential for cardiac electrical coupling, but its effects on myocardial fibrosis is controversial. Here, we analyzed the role of Cx43 in myocardial fibrosis caused by angiotensin II (AngII) using Cx43fl/fl and Cx43Cre-ER(T)/fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b57c473fb35f8334f822afa41634bc
https://hdl.handle.net/11351/5195

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Opposite Effects of Moderate and Extreme Cx43 Deficiency in Conditional Cx43-Deficient Mice on Angiotensin II-Induced Cardiac Fibrosis.

Autor: Valls-Lacalle L; Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Departament de Medicina, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. laura.valls@vhir.org.; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. laura.valls@vhir.org., Negre-Pujol C; Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Departament de Medicina, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. corall_np@hotmail.com.; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. corall_np@hotmail.com., Rodríguez C; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. CRodriguezS@santpau.cat.; Institut de Recerca del Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, 08041 Barcelona, Spain. CRodriguezS@santpau.cat., Varona S; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. SVarona@santpau.cat.; Instituto de Investigaciones Biomédicas de Barcelona (IIBB-CSIC), IIB-Sant Pau, 08041 Barcelona, Spain. SVarona@santpau.cat., Valera-Cañellas A; Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Departament de Medicina, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. tonivalerac@hotmail.com.; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. tonivalerac@hotmail.com., Consegal M; Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Departament de Medicina, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. marta.consegal@vhir.org.; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. marta.consegal@vhir.org., Martínez-González J; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. JMartinezG@santpau.cat.; Instituto de Investigaciones Biomédicas de Barcelona (IIBB-CSIC), IIB-Sant Pau, 08041 Barcelona, Spain. JMartinezG@santpau.cat., Rodríguez-Sinovas A; Cardiovascular Diseases Research Group, Department of Cardiology, Vall d'Hebron University Hospital and Research Institute, Universitat Autònoma de Barcelona, Departament de Medicina, Pg. Vall d'Hebron 119-129, 08035 Barcelona, Spain. antonio.rodriguez.sinovas@vhir.org.; Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain. antonio.rodriguez.sinovas@vhir.org.

Publikováno v: Cells [Cells] 2019 Oct 22; Vol. 8 (10). Date of Electronic Publication: 2019 Oct 22.