Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Valentyn Mohylyuk"'
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1100 (2024)
The deformulation stage of original drug products, which includes the quantification of critical excipients, is crucial for the successful development of generic drug products of solid dosage form. Sodium lauryl sulphate (SLS) belongs to the group of
Externí odkaz:
https://doaj.org/article/72042a92e41844289e8369a0fae563c3
The Increase in the Plasticity of Microcrystalline Cellulose Spheres’ When Loaded with a Plasticizer
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 945 (2024)
Compaction pressure can induce an undesirable solid-state polymorphic transition in drugs, fragmentation, loss of coated pellet integrity, and the decreased viability and vitality of microorganisms. Thus, the excipients with increased plasticity can
Externí odkaz:
https://doaj.org/article/cfcf1c3474be446f8188e3dcd3a0a182
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 586 (2024)
The bitter drug, warfarin, has a narrow therapeutic index (NTI) and is used in paediatrics and geriatrics. The aim of this feasibility study was to formulate the taste-masked warfarin-containing pellets to be applicable for dose personalisation and t
Externí odkaz:
https://doaj.org/article/2bd702a8af0d4abc81596d9e8714728c
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 362 (2024)
Using microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4) with brittle behaviour under compaction is very popular in the pharmaceutical industry for achieving desirable structural–mechanical properties o
Externí odkaz:
https://doaj.org/article/729a9c0f1e3348e8993236f444a39c33
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1407 (2023)
Flavonoids are hydroxylated polyphenols that are widely distributed in plants with diverse health benefits. Despite their popularity, the bioavailability of flavonoids is often overlooked, impacting their efficacy and the comparison of products. The
Externí odkaz:
https://doaj.org/article/b488b50b958347c7bc78d336d11a151b
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
The pharmaceutical industry has a growing interest in continuous manufacturing, particularly for high-volume dosage forms such as solid oral tablets. This is driven by the obvious benefits such as small footprint, batch size flexibility, the relative
Externí odkaz:
https://doaj.org/article/48d673da210b4c50a43f56360c2b49fc
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
The aim of this study was to prepare tablets that offer an immediate release (IR) of the loaded active ingredient using fused deposition modelling (FDM) 3D printing. Hydrochlorothiazide (HCTZ) was used as a model drug, with polyvinyl alcohol (PVA) as
Externí odkaz:
https://doaj.org/article/3c17eb911a56404dbdfa7526ddaee9a1
Autor:
Valentyn Mohylyuk, Dace Bandere
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1236 (2023)
The aim of this feasibility study was to investigate the possibility of producing industrial-scale relevant, robust, high drug-loaded (90.9%, w/w) 100 mg dose immediate-release tablets of isoniazid and simultaneously meet the biowaiver requirements.
Externí odkaz:
https://doaj.org/article/77570a89844748f0b8860b023a94d5ce
Autor:
Valentyn Mohylyuk
Publikováno v:
Mohylyuk, V 2022, ' Effect of roll compaction pressure on the properties of high drug-loaded piracetam granules and tablets ', Drug Development and Industrial Pharmacy, vol. 48, no. 9, pp. 425-437 . https://doi.org/10.1080/03639045.2022.2123499
ObjectiveThe aim of this study was to use an alternative granulation technique, solventless roll compaction, and to investigate the effect of the roll compaction pressure on the properties of granules and high-drug-loaded (80%, w/w) immediate release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a056132f12ceaeafe059808dd5763aae
https://doi.org/10.1080/03639045.2022.2123499
https://doi.org/10.1080/03639045.2022.2123499
Autor:
Igori Balta, Eugenia Butucel, Valentyn Mohylyuk, Adriana Criste, Daniel Severus Dezmirean, Lavinia Stef, Ioan Pet, Nicolae Corcionivoschi
Publikováno v:
Diseases, Vol 9, Iss 3, p 60 (2021)
In recent years, probiotics have attracted public attention and transformed the social perception of microorganisms, convening a beneficial role/state on human health. With aging, the immune system, body physiology, and intestinal microbiota tend to
Externí odkaz:
https://doaj.org/article/528ba1ebea4847c6adb2cba537df82d3