Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Valentinos, Zachariou"'
Autor:
Doaa G. Ali, Ahmed A. Bahrani, Riham H. El Khouli, Brian T. Gold, Yang Jiang, Valentinos Zachariou, Donna M. Wilcock, Gregory A. Jicha
Publikováno v:
Brain and Behavior, Vol 13, Iss 10, Pp n/a-n/a (2023)
Abstract Background and purpose Cerebral small vessel disease (SVD) has been suggested to contribute to the pathogenesis of Alzheimer's disease (AD). Yet, the role of SVD in potentially contributing to AD pathology is unclear. The main objective of t
Externí odkaz:
https://doaj.org/article/0d0f70b7ee994f5a8678563cd851c043
Autor:
Christopher E. Bauer, Valentinos Zachariou, Tiffany L. Sudduth, Linda J. Van Eldik, Gregory A. Jicha, Peter T. Nelson, Donna M. Wilcock, Brian T. Gold
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction We evaluated the relationship between plasma levels of transactive response DNA binding protein of 43 kDa (TDP‐43) and neuroimaging (magnetic resonance imaging [MRI]) measures of brain structure in aging. Methods Plasma sample
Externí odkaz:
https://doaj.org/article/5ef99e64ce4a47b0a8e07bb46021b785
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Multi-compartment diffusion MRI metrics [such as metrics from free water elimination diffusion tensor imaging (FWE-DTI) and neurite orientation dispersion and density imaging (NODDI)] may reflect more specific underlying white-matter tract characteri
Externí odkaz:
https://doaj.org/article/b9b9e0b2d11e4befaab8d21d5c6d469a
Autor:
Timothy J. Libecap, Valentinos Zachariou, Christopher E. Bauer, Donna M. Wilcock, Gregory A. Jicha, Flavius D. Raslau, Brian T. Gold
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Emerging evidence suggests that enlarged perivascular spaces (ePVS) may be a clinically significant neuroimaging marker of global cognitive function related to cerebral small vessel disease (cSVD). We tested this possibility by assessing the relation
Externí odkaz:
https://doaj.org/article/ce4b56fde46d46ada7ce81e14d38b9b9
Publikováno v:
NeuroImage, Vol 249, Iss , Pp 118835- (2022)
Quantitative susceptibility mapping (QSM) is an MRI-based, computational method for anatomically localizing and measuring concentrations of specific biomarkers in tissue such as iron. Growing research suggests QSM is a viable method for evaluating th
Externí odkaz:
https://doaj.org/article/96e2a521789b486d814b8ab9be137dd2
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Cerebral white matter hyperintensities (WMHs) represent macrostructural brain damage associated with various etiologies. However, the relative contributions of various etiologies to WMH volume, as assessed via different neuroimaging measures, is not
Externí odkaz:
https://doaj.org/article/a3b20c91093c478c811777150a91cc76
Autor:
Valentinos Zachariou, Christopher E. Bauer, Elayna R. Seago, Flavius D. Raslau, David K. Powell, Brian T. Gold
Publikováno v:
NeuroImage, Vol 223, Iss , Pp 117309- (2020)
Excessive brain iron negatively affects working memory and related processes but the impact of cortical iron on task-relevant, cortical brain networks is unknown. We hypothesized that high cortical iron concentration may disrupt functional circuitry
Externí odkaz:
https://doaj.org/article/843d5be35daf4a3a8f1f9a8475bf328b
Autor:
T.J. Libecap, Christopher E. Bauer, Valentinos Zachariou, Colleen A. Pappas, Flavius D. Raslau, Peiying Liu, Hanzhang Lu, Brian T. Gold
1.AbstractBackgroundIncreasing evidence suggests that enlarged perivascular spaces (ePVS) are associated with cognitive dysfunction in aging. However, the etiology of ePVS remains unknown. Here we tested the possibility that baseline cerebrovascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7132acb4b60d20a22de76ad412336f98
https://doi.org/10.1101/2023.05.14.23289968
https://doi.org/10.1101/2023.05.14.23289968
Autor:
Timothy Justin Libecap, Christopher E. Bauer, Valentinos Zachariou, Flavius D Raslau, Brian T. Gold
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbfe571e29a0fbb735ead91f12625ef1
https://doi.org/10.1002/alz.060797
https://doi.org/10.1002/alz.060797
Publikováno v:
Cerebral cortex (New York, N.Y. : 1991).
Aging is associated with brain iron accumulation, which has been linked to cognitive decline. However, how brain iron affects the structure and function of cognitive brain networks remains unclear. Here, we explored the possibility that iron load in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af609cff98c873822486e7a562957d3
https://pubmed.ncbi.nlm.nih.gov/36182267
https://pubmed.ncbi.nlm.nih.gov/36182267