Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Valentino Parravicini"'
Autor:
Kalle Söderström, Andre Simoes, Andrew Hutton, Rebecca Alade, Istvan Kovacs, Mihil Patel, Oliver Nussbaumer, Daniel W. Fowler, Joanna Kawalkowska, Victoria Hillerdal, Michael Koslowski, Tim Recaldin, Alice Brown, Elizabeth Reynolds, Katharina Bergerhoff, Valentino Parravicini
Publikováno v:
Cancer Research. 80:888-888
The treatment of haematologic malignancies with adoptive cell therapy is largely limited to platforms based on patient-derived, autologous αβ T cells. Although successful, this approach comes with challenges including associated toxicities, risk of
Autor:
Kirsty E Waddington, Céline Gongora, Lauren C. Davis, Valentino Parravicini, Zuni I. Bassi, Emma J. Roberts, Philip G. Humphreys, Darcy E. Lewis, Abigail L. Macmillan-Jones, Ian Churcher, Afjal Hussain Miah, Claire Maller, Martin Christian Fillmore, David F. Tough, Rab K. Prinjha, Trevor D. Chapman, Nicholas Galwey
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2018, 13 (10), pp.2862-2867. ⟨10.1021/acschembio.8b00705⟩
ACS Chemical Biology, American Chemical Society, 2018, 13 (10), pp.2862-2867. ⟨10.1021/acschembio.8b00705⟩
International audience; P300/CBP-associated factor (PCAF) and general control nonderepressible 5 (GCN5) are closely related epigenetic proteins, each containing an acetyltransferase domain and a bromodomain. Consistent with reported roles for these p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c5bb8cca887d5d0f7bce8ff15277f8
https://hal.umontpellier.fr/hal-02284859
https://hal.umontpellier.fr/hal-02284859
Autor:
Marie S. Chen, Valentino Parravicini, Rab K. Prinjha, Inmaculada Rioja, Alexander Tarakhovsky, Astrid Stienen, Ingrid Mecklenbräuker, Kevin Lee, Terry C. Fang, Charles M. Rice, Scott Dewell, Rohit Chandwani, Margaret R. MacDonald, Uwe Schaefer
Publikováno v:
The Journal of Experimental Medicine
Di-methylation of histone H3 at lysine 9 (H3K9me2) suppresses expression of interferon genes, and deletion or inactivation of the lysine methyltransferase G9a converts fibroblasts into interferon-producing cells resistant to RNA viruses.
Effecti
Effecti
Autor:
Valentino Parravicini, Anne-Christine Field, Rose Zamoyska, M. Albert Basson, Peter Tomlinson
Publikováno v:
Blood. 111:4273-7282
E3 ubiquitin ligases determine which intracellular proteins are targets of the ubiquitin conjugation pathway and thus play a key role in determining the half-life, subcellular localization and/or activation status of their target proteins. Itchy mice
Publikováno v:
Molecular and Cellular Biology. 26:8655-8665
The src family kinases p56lck (Lck) and p59fyn (Fyn) are the most proximal signaling molecules to be activated downstream of the T-cell receptor. Using an inducible transgenic model, we can regulate the expression of Lck in primary T cells and ask ho
Publikováno v:
Allergy & Clinical Immunology International - Journal of the World Allergy Organization. 14:0025-0036
Publikováno v:
Journal of Leukocyte Biology. 69:831-840
We investigated possible expression and function in mast cells of protein kinase C (PKC) theta, a member of the PKC family with demonstrated function in a limited range of cell types. We found that PKC theta is expressed in bone marrow-derived mast c
Autor:
Valentino Parravicini, Stefano Caserta
Publikováno v:
Molecular interventions. 10(4)
Autor:
Valentino, Parravicini, Anne-Christine, Field, Peter D, Tomlinson, M Albert, Basson, Rose, Zamoyska
Publikováno v:
Blood. 111(8)
E3 ubiquitin ligases determine which intracellular proteins are targets of the ubiquitin conjugation pathway and thus play a key role in determining the half-life, subcellular localization and/or activation status of their target proteins. Itchy mice
Autor:
Yasuko Furumoto, Valentino Parravicini, Claudia González-Espinosa, Juan Rivera, Sandra Odom, John J. Ryan, Gregorio Gomez, Martina Kovarova
Publikováno v:
Immunologic research. 30(2)
Antigen-induced cross-linking of immunoglobulin E (IgE) antibodies bound to the high-affinity IgE receptor (FcepsilonRI), on mast cells results in the release of mediators that initiate an inflammatory response. This normal immune response has been a