Výsledky vyhledávání - "Valentino Cattori"

Akademický článek

FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP

Autor: Mirjam Lutz, Aline R. Steiner, Valentino Cattori, Regina Hofmann-Lehmann, Hans Lutz, Anja Kipar, Marina L. Meli

Publikováno v: Pathogens, Vol 9, Iss 8, p 603 (2020)

Feline Infectious Peritonitis (FIP)—the deadliest infectious disease of young cats in shelters or catteries—is induced by highly virulent feline coronaviruses (FCoVs) emerging in infected hosts after mutations of less virulent FCoVs. Previous stu

Externí odkaz: https://doaj.org/article/b44ec15aa6634e75bd6a9055971a89b9

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Akademický článek

Feline leukemia virus and other pathogens as important threats to the survival of the critically endangered Iberian lynx (Lynx pardinus).

Autor: Marina L Meli, Valentino Cattori, Fernando Martínez, Guillermo López, Astrid Vargas, Miguel A Simón, Irene Zorrilla, Alvaro Muñoz, Francisco Palomares, Jose V López-Bao, Josep Pastor, Ravi Tandon, Barbara Willi, Regina Hofmann-Lehmann, Hans Lutz

Publikováno v: PLoS ONE, Vol 4, Iss 3, p e4744 (2009)

The Iberian lynx (Lynx pardinus) is considered the most endangered felid species in the world. In order to save this species, the Spanish authorities implemented a captive breeding program recruiting lynxes from the wild. In this context, a retrospec

Externí odkaz: https://doaj.org/article/44ea7a1be1554049b3b1072954fb6eb0

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FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP

Autor: Aline R Steiner, Mirjam Lutz, Valentino Cattori, Marina L. Meli, Regina Hofmann-Lehmann, Anja Kipar, Hans Lutz

Publikováno v: Pathogens
Volume 9
Issue 8
Pathogens, Vol 9, Iss 603, p 603 (2020)

Feline infectious peritonitis (FIP)&mdash
the deadliest infectious disease of young cats in shelters or catteries&mdash
is induced by highly virulent feline coronaviruses (FCoVs) emerging in infected hosts after mutations of less virulent F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d3104a189732a2a23ba9e9020da88c
https://doi.org/10.3390/pathogens9080603

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Abstract C040: INTH-454, a p300/CBP interactome modulator, targets multiple pathogenesis factors in solid tumors and induces strong anti-proliferative effects in vitro and in vivo as single agent

Autor: Bernd Hentsch, Ulrich Kessler, Valentino Cattori

Publikováno v: Molecular Cancer Therapeutics. 18:C040-C040

Background: INTH-454 is a novel rationally designed ligand of the CH1/TAZ1 domain of p300/CBP, two closely related paralog transcription co-activators crucially involved in cancer cell proliferation and tumor progression. Here, we report the in vitro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cf5e44fb017c2a6968dabbbc402e190
https://doi.org/10.1158/1535-7163.targ-19-c040

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Abstract 2694: A first-in-class small-molecule modulator of the p300/CBP interactome exhibits broad efficacy in xenograft models of solid tumors and hematologic malignancies

Autor: Marc Labelle, Bernd Hentsch, Valentino Cattori, Ulrich Kessler

Publikováno v: Cancer Research. 79:2694-2694

Background: Dysregulation of the cellular transcription machinery is a fundamental feature of cancer. E1A binding protein (p300) and CREB binding protein (CBP) are two closely related paralog transcription co-activators involved in the expression of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9d59a9c19f058c39993a97aa092dcca
https://doi.org/10.1158/1538-7445.am2019-2694

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The genetic diversity and phenotypic associations of feline caliciviruses from cats in Switzerland

Autor: Valentino Cattori, Marina L. Meli, Regina Hofmann-Lehmann, Andrea M. Spiri, Oliver G. Pybus, Barbara Willi, Adolf Steinrigl, Alice Berger, Julien Thézé

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2016, 97 (12), pp.3253-3266. ⟨10.1099/jgv.0.000622⟩

International audience; Feline calicivirus (FCV) is a common viral pathogen in domestic cats worldwide. The variable regions of the capsid (VP1) gene of FCV have one of the highest recorded rates of molecular evolution. Understanding the genetic dive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e601933679bed71502112c9c61f75d
https://doi.org/10.1099/jgv.0.000622

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Inhibition of Feline leukemia virus replication by the integrase inhibitor Raltegravir

Autor: Valentino Cattori, Beatrice Weibel, Hans Lutz

Publikováno v: Veterinary Microbiology. 152:165-168

The oncogenic gammaretrovirus Feline leukemia virus (FeLV) has been the leading cause of death among domestic cats until the introduction of efficient diagnostics and vaccines in the late 1980s. So far, no efficient treatment for viremic animals is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc898145470e35db3f4b7e44fd9161e5
https://doi.org/10.1016/j.vetmic.2011.03.039

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Identification, Molecular Characterization, and Occurrence of Two Bovine Hemoplasma Species in Swiss Cattle and Development of Real-Time TaqMan Quantitative PCR Assays for Diagnosis of Bovine Hemoplasma Infections

Autor: Regina Hofmann-Lehmann, Hans Lutz, Ute M. Dreher, Gabriela Knubben-Schweizer, Karl Nuss, Valentino Cattori, Ueli Braun, Marina L. Meli, Barbara Willi

Publikováno v: Journal of Clinical Microbiology. 48:3563-3568

Concomitantly with an outbreak of fatal anaplasmosis in a cattle herd in Switzerland in 2002, we detected two bovine hemoplasma species in diseased animals: Mycoplasma wenyonii (formerly Eperythrozoon wenyonii ) and a second, novel bovine hemoplasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3ebf5b19660a315912fdbfda4298d9
https://doi.org/10.1128/jcm.02224-09

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Oral small molecule modulators of p300/CBP to reprogram cancer cells and reactivate the p53 pathway in HPV-associated carcinomas

Autor: Bernd Hentsch, Marc Labelle, Ulrich Kessler, Valentino Cattori

Publikováno v: Journal of Clinical Oncology. 36:e14581-e14581

e14581Background: Dysregulation of the basal cellular transcription machinery is a fundamental feature of cancer. E1A binding protein (p300) and CREB binding protein (CBP) are two closely related p...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b7de77ea452219a773ce2fb09caac91
https://doi.org/10.1200/jco.2018.36.15_suppl.e14581

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The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcome

Autor: Ravi Tandon, Hans Lutz, Barbara Riond, Regina Hofmann-Lehmann, Valentino Cattori, Andrea C. Pepin

Publikováno v: Veterinary Microbiology. 133:292-296

Feline leukaemia virus (FeLV) infection in felids results mainly from oronasal exposure to infectious saliva and nasal secretions, but the potential for viral transmission through faeces and urine has not been completely characterized. In order to as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d886706e4707dbd2bc3f34ca5a4b445
https://doi.org/10.1016/j.vetmic.2008.07.001

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