Development and validation of a liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of serotonin and thromboxane B2 from activated platelets

Autor: Jonathan Evrard, Lionel Pochet, Valentine Minet, Jean-Michel Dogné, François Mullier, Christelle Vancraeynest

Publikováno v: International Journal of Laboratory Hematology. 40:663-671

Introduction: Availability of a rapid and reliable platelet activation assay avoiding limitations of current techniques would be valuable to diagnose heparin-induced thrombocytopenia and platelet secretion disorders. Objectives: The first aim was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b6e4ed087f0c4ec4fd30304662db26
https://doi.org/10.1111/ijlh.12901

Rapid exclusion of the diagnosis of immune HIT by AcuStar HIT and heparin-induced multiple electrode aggregometry

Autor: Sarah Lessire, François Mullier, Nicolas Bailly, Jean-Michel Dogné, Bernard Chatelain, Valentine Minet, Bérangère Devalet, Jonathan Douxfils, Justine Baudar, Julie Laloy, Maximilien Gourdin

Publikováno v: Minet, V, Baudar, J, Bailly, N, Douxfils, J, Laloy, J, Lessire, S, Gourdin, M, Devalet, B, Chatelain, B, Dogné, J M & Mullier, F 2014, ' Rapid exclusion of the diagnosis of immune HIT by AcuStar HIT and heparin-induced multiple electrode aggregometry ', Thrombosis Research, vol. 133, no. 6, pp. 1074-1078 . https://doi.org/10.1016/j.thromres.2014.01.014

Background Accurate diagnosis of heparin-induced thrombocytopenia (HIT) is essential but remains challenging. We have previously demonstrated, in a retrospective study, the usefulness of the combination of the 4Ts score, AcuStar HIT and heparin-induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4c637dc22dae2ef9c0d032f44461f5
https://doi.org/10.1016/j.thromres.2014.01.014

Heparin-induced multi-electrode aggregometry method for heparin-induced thrombocytopenia testing: communication from the SSC of the ISTH

Autor: Tamam Bakchoul, Vasiliki Gkalea, François Mullier, Valentine Minet, Marie-Christine Morel-Kopp, Ismail Elalamy, Chris Ward

Publikováno v: Journal of thrombosis and haemostasis : JTH. 14(12)

Heparin-induced thrombocytopenia (HIT) is a rare life-threatening complication of exposure to unfractionated/LMW heparin [1]. HIT diagnosis remains challenging, needing careful review of the clinical history and sensitive laboratory assays. Pre-test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ab4e2ffc22e82130c62ed8e5271f8b
https://pubmed.ncbi.nlm.nih.gov/27864862

Functional Assays in the Diagnosis of Heparin-Induced Thrombocytopenia: A Review

Autor: Valentine Minet, Jean-Michel Dogné, François Mullier

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Minet, V, Dogné, J M & Mullier, F 2017, ' Functional assays in the diagnosis of heparin-induced thrombocytopenia : A review ', Molecules, vol. 22, no. 4, 617 . https://doi.org/10.3390/molecules22040617
Molecules : a journal of synthetic organic and natural product chemistry, Vol. 22, no. 4, p. 617 [1-24] (2017)

A rapid and accurate diagnosis in patients with suspected heparin-induced thrombocytopenia (HIT) is essential for patient management but remains challenging. Current HIT diagnosis ideally relies on a combination of clinical information, immunoassay a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc0072b8a83db7314caea8038efbd2a
https://doi.org/10.3390/molecules22040617

Dabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All‐Cause Mortality: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Autor: Véronique Rabenda, Olivier Bruyère, François Mullier, Jean-Yves Reginster, Fanny Buckinx, Valentine Minet, Jonathan Douxfils, Jean-Michel Dogné, Philippe Hainaut

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Douxfils, J, Buckinx, F, Mullier, F, Minet, V, Rabenda, V, Reginster, J-Y, Hainaut, P, Bruyère, O & Dogné, J-M 2014, ' Dabigatran Etexilate and Risk of Myocardial Infarction, Other Cardiovascular Events, Major Bleeding, and All-Cause Mortality : A Systematic Review and Meta-analysis of Randomized Controlled Trials ', Journal of the American Heart Association, vol. 3, no. 3, 000515 . https://doi.org/10.1161/JAHA.113.000515

Background Signals of an increased risk of myocardial infarction ( MI ) have been identified with dabigatran etexilate in randomized controlled trials ( RCTs ). Methods and Resules We conducted searches of the published literature and a clinical tria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f026b48f59af2291243684c45b3742dd
https://doi.org/10.1161/jaha.113.000515