Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Valentine Charlton-Menys"'
Autor:
Harshal A. Deshmukh, Helen M. Colhoun, Toby Johnson, Paul M. McKeigue, D. John Betteridge, Paul N. Durrington, John H. Fuller, Shona Livingstone, Valentine Charlton-Menys, Andrew Neil, Neil Poulter, Peter Sever, Denis C. Shields, Alice V. Stanton, Aurobindo Chatterjee, Craig Hyde, Roberto A. Calle, David A. DeMicco, Stella Trompet, Iris Postmus, Ian Ford, J. Wouter Jukema, Mark Caulfield, Graham A. Hitman
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 1000-1011 (2012)
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and th
Externí odkaz:
https://doaj.org/article/0e30b62ae4ad49fe9ad70c633f99fac3
Autor:
Paul N. Durrington, D. John Betteridge, H. Andrew W. Neil, Coen D.A. Stehouwer, Casper G. Schalkwijk, Helen M. Colhoun, David A. DeMicco, Graham A. Hitman, Valentine Charlton-Menys, Shona J. Livingstone, Gregory M. Preston, Weihang Bao, Sabita S. Soedamah-Muthu, John H. Fuller
Publikováno v:
Diabetologia 58 (2015) 7
Diabetologia, 58(7), 1494-1502. Springer, Cham
Diabetologia, 58(7), 1494-1502
Diabetologia
Diabetologia, 58(7), 1494-1502. Springer, Cham
Diabetologia, 58(7), 1494-1502
Diabetologia
Aims/hypothesis We investigated whether atorvastatin 10 mg daily lowered C-reactive protein (CRP) and whether the effects of atorvastatin on cardiovascular disease (CVD) varied by achieved levels of CRP and LDL-cholesterol. Methods CRP levels were me
Autor:
Nahla N Younis, Mohamed M. Elseweidy, Paul N. Durrington, Philip W. Pemberton, Handrean Soran, Valentine Charlton-Menys
Publikováno v:
Clinical Science. 124:343-349
Glycation of apoB (apolipoprotein B) of LDL (low-density lipoprotein) increases its atherogenicity. Concentrations of both serum glyc-apoB (glycated apoB) and SD-LDL (small dense LDL) (syn LDL3; D=1.044–1.063 g/ml) are increased in diabetes and are
Autor:
Paul N. Durrington, Nahla N Younis, Reena Sharma, Handrean Soran, Philip W. Pemberton, Valentine Charlton-Menys, Salam Hama, Mohamed M. Elseweidy
Publikováno v:
Diabetes and Vascular Disease Research. 10:152-160
Glycation of low-density lipoprotein (LDL) increases its atherogenicity, but whether high-density lipoprotein (HDL) can protect LDL against glycation is not known. LDL and HDL were isolated from 32 volunteers with serum HDL cholesterol concentrations
Autor:
Handrean Soran, Michael W France, See Kwok, Sanjaya Dissanayake, Valentine Charlton-Menys, Nahla N Younis, Paul N Durrington
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 48:566-571
Introduction Clinical trials have shown that apolipoprotein B100 (apoB) is better than calculated low-density lipoprotein cholesterol (c-LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C) as a target for statin treatment. However, there a
Autor:
Kathryn C.B. Tan, Weihang Bao, David A. DeMicco, Valentine Charlton-Menys, D. John Betteridge, John H. Fuller, Gregory M. Preston, Shona Livingstone, Graham A. Hitman, Helen M. Colhoun, Harshal Deshmukh, Paul N. Durrington, Andrew Neil
Publikováno v:
Diabetes. 60:2379-2385
OBJECTIVE Circulating levels of soluble receptor for advanced glycation end products (sRAGE) likely comprise both a secreted isoform (esRAGE) and wild-type RAGE cleaved from the cell membrane. Both sRAGE and esRAGE have been proposed as biomarkers of
Autor:
P Pemberton, Narinder Bansal, Paul N. Durrington, Simon G. Anderson, A. Vyas, John Charles Oldroyd, Valentine Charlton-Menys, Peter E. Clayton, J. Kennedy Cruickshank, Isla Gemmell
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 96:2567-2574
Adiponectin, high-density lipoprotein cholesterol (HDL-C) and insulin concentrations may be important in the pathophysiology of cardiovascular disease.We tested the hypothesis that serum adiponectin rather than insulin differs from early life, betwee
Autor:
John Kennedy Cruickshank, R. R. Davies, Paul N. Durrington, J. M. Gibson, J. Dean, P. G. Wiles, Valentine Charlton-Menys, Chris Roberts, Philip A. Kalra, A. Moorhouse, P. Jinadev, Matthew Gittins, Martin K. Rutter, H. R. Prais
Publikováno v:
Diabetic Medicine. 28:100-108
AIMS: To compare the renal effects of low- vs. high-dose atorvastatin in patients with Type 2 diabetes mellitus and optimally managed early renal disease. METHODS: We compared the 2-year progression of nephropathy in a double-blind randomized control
Autor:
Robert A. Hegele, Grahame Wood, Paul N. Durrington, Emyr W. Benbow, Ian Roberts, Jian Wang, Handrean Soran, Valentine Charlton-Menys
Publikováno v:
Journal of Clinical Lipidology. 4:310-313
Cardiovascular Research Group, School of Clinical & Laboratory Sciences, University of Manchester, Core Technology Facility (3 Floor), 46 Grafton Street, Manchester, M13 9NT, United Kingdom (Drs. Soran, Charlton-Menys, and Durrington); Robarts Resear
Autor:
Tracey E. Toms, Josh Dixey, Suzy Silburn, Elena Nikiphorou, Clive Kelly, Muhammad Iskandar, Paola de Pablo, Jacek Polanski, Vadivelu Saravanan, Krzysztof Dudek, Deborah Palmer, Iain B. McInnes, R. N. Thompson, Raylynne Rai, Rosemary Waller, Usman Ahmed, Tom Fardon, Janis Baird, Andrew J. K. Östör, Kimme L. Hyrich, Hoda Mirjafari, Christopher L. Buckley, Fiona M McQueen, Nicola Dalbeth, David Collins, Hanan Sayed M. Abozaid, Alison Jordan, P. Prouse, Christopher D. Buckley, Resmy Suresh, Nick Amos, Sophia Steer, R. Klocke, Elizabeth J. Coulson, Kin S. Long, Jet J C S Veldhuijzen van Zanten, Jennifer Hamilton, Nigel Cox, Yiannis Koutedakis, William G Dixon, Sally Youssef, David Scott, Paul J. Thornalley, Ruth Gordon, Sarah L. Westlake, David A. Walsh, Tarnya Marshall, Louise K. Mercer, Rachel Tsang, Deborah Symmons, Valentine Charlton-Menys, Gouri Koduri, William R. Ferrell, Anne Crilly, George D. Kitas, Jagdish R. Nair, Ernest Choy, Yasser El Miedany, Alexandra N. Colebatch, Joanna M. Ledingham, Peter Nightingale, Ian N. Bruce, Richard A. Watts, Natalie Horwood, Cristina Estrach, Elizabeth Toberty, Sam Norton, Izabella Uchmanowicz, Suzanne M M Verstappen, Giorgos S. Metsios, Peter Williams, Carol Heycock, Sangita Sathyamurthy, Patrick A. Kiely, A E Litwic, Lyn Williamson, Deborah P M Symmons, Sarang Chitale, Naila Rabbani, Maria Lobo, Douglas Carroll, Beata Jankowska, Tracy Arnold, Maria Juarez, Maha El Gaafary, J. Braun, Gina Allen, James Galloway, Tracey M Farragher, Gabrielle Kingsley, Rachael Steven, Karen M J Douglas, T. Pullar, Andrew Filer, Elizabeth Price, Catherine Gwynne, Martin Rynne, Kath D. Watson, Richard O. Williams, G. Hirsch, Diane Bunn, Julia L. Newton, Adam Young, Antonios Stavropoulos-Kalinoglou, Devesh Mewar, Aamer Sandoo, Vasileios F. Panoulas, Jeremy Camilleri, Kumar Vinod, Ian C. Scott, Mark T. Quinn, Zaeem Cader, Neil Snowden, Jacqueline P. Smith, Lunt Mark, Paresh Jobanputra, John C. Lockhart, Nicola J Goodson, Christopher J Edwards, Anthony Doyle, Karim Raza, Natasha Jones, Nihal A. Fathi, Ravi Suppiah
Publikováno v:
Rheumatology. 49:i155-i167