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A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer.

Autor: Khan, Mairah T., Irlam-Jones, Joely J., Pereira, Ronnie Rodrigues, Lane, Brian, Valentine, Helen R., Aragaki, Kai, Dyrskjøt, Lars, McConkey, David J., Hoskin, Peter J., Choudhury, Ananya, West, Catharine M. L.

Publikováno v: British Journal of Cancer; Jul2021, Vol. 125 Issue 1, p85-93, 9p

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

Autor: Burrows, Natalie, Williams, Joseph, Telfer, Brian A, Resch, Julia, Valentine, Helen R, Fitzmaurice, Richard J, Eustace, Amanda, Irlam, Joely, Rowling, Emily J, Hoang-Vu, Cuong, West, Catharine M, Brabant, Georg, Williams, Kaye J

Publikováno v: Oncotarget
Burrows, N, Williams, J, Telfer, B, Resch, J, Valentine, H, Fitzmaurice, R, Eustace, A, Irlam, J, Rowling, E, Hoang-Vu, C, West, C, Brabant, G & Williams, K 2016, ' Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas ', Oncotarget, vol. 7, no. 39, pp. 63106-63123 . https://doi.org/10.18632/oncotarget.11056

Anaplastic (ATC) and certain follicular thyroid-carcinomas (FTCs) are radioresistant. The Phosphatidylinositide 3-kinase (PI3K) pathway is commonly hyperactivated in thyroid-carcinomas. PI3K can modify the PI3K-related kinases (PIKKs) in response to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1cabff1e987a84a7d9c621a2069a7a
https://www.repository.cam.ac.uk/handle/1810/323031

Low density array profiling of head and neck squamous cell carcinoma utilizing a 25-gene signature can reliably identify hypoxic tumors

Autor: Williamson, Amanda, Betts, Guy N. J., Patiar, Shalini, Valentine, Helen R., Irlam, Joely J., Ramachandran, Anassuya, Ashirwad Merve, Homer, Jarrod J., Moller-Levet, Carla, Buffa, Franscesca M., Hall, Gillian, Miller, Crispin J., Harris, Adrian L., West, Catharine M. L.

Publikováno v: Web of Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e65e268c3618b56aa7150edc89ea0a86
https://publons.com/wos-op/publon/12962493/

Hypoxia-inducible factor 1alpha expression as an intrinsic marker of hypoxia: correlation with tumor oxygen, pimonidazole measurements, and outcome in locally advanced carcinoma of the cervix.

Autor: Hutchison GJ; Academic Department of Radiation Oncology, The University of Manchester, Christie Hospital NHS Trust, Manchester, United Kingdom., Valentine HR, Loncaster JA, Davidson SE, Hunter RD, Roberts SA, Harris AL, Stratford IJ, Price PM, West CM

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2004 Dec 15; Vol. 10 (24), pp. 8405-12.