Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Valentina Zuckerman"'
Autor:
Bing-Yi Wang, Zhijie Charles Chen, Mohajeet Bhuckory, Tiffany Huang, Andrew Shin, Valentina Zuckerman, Elton Ho, Ethan Rosenfeld, Ludwig Galambos, Theodore Kamins, Keith Mathieson, Daniel Palanker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Retinal prosthetics has shown its promise in restoring vision, despite limited acuity. Here, the authors demonstrate a high-resolution prosthetic vision that enables grating acuity matching the natural visual resolution in rats, paving the way to hig
Externí odkaz:
https://doaj.org/article/5b227fbdb0454f6aaa871b26e10b8c6f
Autor:
Kevin C. Boyle, Valentina Zuckerman, Thomas Flores, Karl Deisseroth, Daniel Palanker, Tong Ling, Charu Ramakrishnan
Publikováno v:
Proc Natl Acad Sci U S A
Neurons undergo nanometer-scale deformations during action potentials, and the underlying mechanism has been actively debated for decades. Previous observations were limited to a single spot or the cell boundary, while movement across the entire neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf37170166f4f7b95835e30908cd3e3
https://doi.org/10.1073/pnas.1920039117
https://doi.org/10.1073/pnas.1920039117
Autor:
Zhijie Charles Chen, Bing-Yi Wang, Mohajeet Bhuckory, Andrew Shin, Elton Ho, Valentina Zuckerman, Ludwig Galambos, Theodore Kamins, Keith Mathieson, Daniel Palanker
Publikováno v:
Ophthalmic Technologies XXXII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d6b6fff450bc9d1a82b7fc057c1312f
https://doi.org/10.1117/12.2608973
https://doi.org/10.1117/12.2608973
Autor:
Ludwig Galambos, Theodore I. Kamins, Bing-Yi Wang, Daniel Palanker, Valentina Zuckerman, Tong Ling, Andrew Shin, Zhijie Charles Chen, Sean Afshar, Elton Ho, Keith Mathieson, James S. Harris, Mohajeet Balveer Bhuckory, Tiffany Wanshing Huang
Publikováno v:
J Neural Eng
Objective. To restore central vision in patients with atrophic age-related macular degeneration, we replace the lost photoreceptors with photovoltaic pixels, which convert light into current and stimulate the secondary retinal neurons. Clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562963281ccdce5d82a35f0f853e36b4
https://doi.org/10.1101/2020.10.28.353128
https://doi.org/10.1101/2020.10.28.353128
Publikováno v:
Quantitative Phase Imaging VI.
Nanometer-scale deformations of the neuron accompany the action potential. These displacements are measured using a fast quantitative phase microscope and averaged in synchrony with optogenetic stimulation of cultured neurons. The phase movie is furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688ace591b4e0d2acd0e3d5765730463
https://doi.org/10.1117/12.2545250
https://doi.org/10.1117/12.2545250
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2020.
We report the full-field imaging of the mechanical deformations accompanying the action potential in primary cortical neurons using ultrafast quantitative phase imaging (QPI) with a temporal resolution of 0.1 ms and a membrane displacement sensitivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da776a0d7bf74e3cc3769cd3c85058e2
https://doi.org/10.1117/12.2543625
https://doi.org/10.1117/12.2543625
Autor:
Karl Deisseroth, Charu Ramakrishnan, Daniel Palanker, Tong Ling, Valentina Zuckerman, Thomas Flores, Kevin C. Boyle
Neurons undergo nanometer-scale deformations during action potentials, and the underlying mechanism has been actively debated for decades. Previous observations were limited to a single spot or the cell boundary, while movement across the entire neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9324d5bd3ecab6e7bfed68fdc6e78aa3
https://doi.org/10.1101/765768
https://doi.org/10.1101/765768
Autor:
Iain H. McKillop, Jacob H. Swet, Victor Showlater, William A. Ahrens, Eugene P. Sokolov, David A. Iannitti, Valentina Zuckerman
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and is characterized by rapid tumor expansion and metastasis. Lysophosphatidic acid (LPA) signaling, via LPA receptors 1–6 (LPARs1–6), regulates diverse cell functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616f38c4ee2143d10e09af9617e62b40
https://doi.org/10.18632/oncotarget.6696
https://doi.org/10.18632/oncotarget.6696
Autor:
Brendon J. Monahan, Ora Schueler-Furman, Martin Scheffner, Ofra Moshel, Yagl Haupt, Patricia A. Pilling, Yong-hui Jiang, Ai-Leen Chan, Dafne Campigli Di Giammartino, Valentina Zuckerman, Sue Haupt, Tamar Grossman
Publikováno v:
Biochemistry. 52:3119-3129
In human papillomavirus (HPV)-infected cells, the p53 tumor suppressor is tightly regulated by the HPV-E6-E6AP complex, which promotes it for proteasomal degradation. We previously demonstrated that c-Abl tyrosine kinase protects p53 from HPV-E6-E6AP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a1a778db1e8db711bff5936ca06d57
https://doi.org/10.1021/bi301710c
https://doi.org/10.1021/bi301710c
Autor:
Grzegorz M. Popowicz, Aart G. Jochemsen, Tamar Grossman, Jean-Christophe Marine, Isabelle Silberman, Kristiaan Lenos, Ygal Haupt, Valentina Zuckerman, Tad A. Holak
Publikováno v:
Journal of Biological Chemistry. 284:4031-4039
Upon exposure to DNA damage the p53 tumor suppressor is accumulated and activated to stall cellular growth. For this to occur, p53 must be relieved from its major inhibitors, Mdm2 (Hdm2 in humans) and Mdmx (Mdm4; Hdmx in humans). A key mechanism cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479e53ff3296e34103756c8489e4f131
https://doi.org/10.1074/jbc.m809211200
https://doi.org/10.1074/jbc.m809211200