Zobrazeno 1 - 10 of 16 pro vyhledávání: '"Valentina Varela"'
2
Akademický článek
The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS
Autor: Mariángeles Kovacs, Catalina Alamón, Cecilia Maciel, Valentina Varela, Sofía Ibarburu, Lucas Tarragó, Peter H. King, Ying Si, Yuri Kwon, Olivier Hermine, Luis Barbeito, Emiliano Trias
Publikováno v: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected C
Externí odkaz: https://doaj.org/article/0bb5a531084d4897a403f95a98d581a9
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3
Akademický článek
Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS
Autor: Emiliano Trias, Pamela R. Beilby, Mariángeles Kovacs, Sofía Ibarburu, Valentina Varela, Romina Barreto-Núñez, Samuel C. Bradford, Joseph S. Beckman, Luis Barbeito
Publikováno v: Frontiers in Aging Neuroscience, Vol 11 (2019)
Age is a recognized risk factor for amyotrophic lateral sclerosis (ALS), a paralytic disease characterized by progressive loss of motor neurons and neuroinflammation. A hallmark of aging is the accumulation of senescent cells. Yet, the pathogenic rol
Externí odkaz: https://doaj.org/article/24663bf2e9884539badf6024476304e9
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4
Akademický článek
Atención integral a los problemas de convivencia familiar, en una comisaría de familia de la ciudad de Cali
Autor: Adriana Mora Anto, Miriam Román Muñoz, Valentina Varela Martínez
Publikováno v: Diversitas: Perspectivas en Psicología, Vol 11, Iss 1, Pp 99-111 (2015)
En esta investigación cualitativa se abordaron los procesos de atención integral a los problemas de convivencia familiar, en la Comisaria de Familia del sector Ladera en Cali, teniendo en cuenta la pers - pectiva de los modelos alternativos de reso
Externí odkaz: https://doaj.org/article/d2ce5c06aa6d4c15b4550ac6b2aa9fc6
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5
The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS
Autor: Olivier Hermine, Mariángeles Kovacs, Ying Si, Luis Barbeito, Emiliano Trias, Valentina Varela, Peter H. King, Cecilia Maciel, Catalina Alamón, Sofía Ibarburu, Yuri Kwon, Lucas Tarragó
Publikováno v: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Acta Neuropathologica Communications
Degeneration of motor neurons, glial cell reactivity, and vascular alterations in the CNS are important neuropathological features of amyotrophic lateral sclerosis (ALS). Immune cells trafficking from the blood also infiltrate the affected CNS parenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8944fa73ea74fedd70704adcb13d64dc
https://doaj.org/article/0bb5a531084d4897a403f95a98d581a9
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7
Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL‐34, and SCF in amyotrophic lateral sclerosis
Autor: Joseph S. Beckman, Valentina Varela, Sofía Ibarburu, Yuri Kwon, Mariángeles Kovacs, Ying Si, Emiliano Trias, Olivier Hermine, Ivan C. Moura, Peter H. King, Luis Barbeito
Publikováno v: Glia
Distal axonopathy is a recognized pathological feature of amyotrophic lateral sclerosis (ALS). In the peripheral nerves of ALS patients, motor axon loss elicits a Wallerian-like degeneration characterized by denervated Schwann cells (SCs) together wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccd8b5c0d7e8b0265c234e887b656a7
https://doi.org/10.1002/glia.23768
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9
Focal Transplantation of Aberrant Glial Cells Carrying the SOD1G93A Mutation into Rat Spinal Cord Induces Extensive Gliosis
Autor: Emiliano Trias, Hugo Peluffo, Sofía Ibarburu, Luis Barbeito, Joseph S. Beckman, Valentina Varela, Romina Barreto-Núñez, Natalia Lago
Publikováno v: Neuroimmunomodulation. 24:143-153
Objective: We aimed to determine the potential of aberrant glial cells (AbAs) isolated from the spinal cord of adult SOD1G93A symptomatic rats to induce gliosis and neuronal damage following focal transplantation into the lumbar spinal cord of wild-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4301398653e519d97eed5653cc2835f
https://doi.org/10.1159/000480639
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10
CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS
Autor: Emiliano Trias, Mariángeles Kovacs, Ivan C. Moura, Peter H. King, Olivier Hermine, Joseph S. Beckman, Sofía Ibarburu, Ying Si, Yuri Kwon, Luis Barbeito, Valentina Varela
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 16, p 3880 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 16
Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of upper and lower motor neurons accompanied by proliferation of reactive microglia in affected regions. However, it is unknown whether the hematopoietic marker CD34 can identify a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3b15dd94eda8bb178af92456243ad3
https://www.mdpi.com/1422-0067/20/16/3880
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