Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Valentina Tedeschi"'
Autor:
Carola Amormino, Emanuela Russo, Valentina Tedeschi, Maria Teresa Fiorillo, Alessandro Paiardini, Francesco Spallotta, Laura Rosanò, Loretta Tuosto, Martina Kunkl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Staphylococcus aureus is a gram-positive bacterium that may cause intestinal inflammation by secreting enterotoxins, which commonly cause food-poisoning and gastrointestinal injuries. Staphylococcal enterotoxin B (SEB) acts as a superantigen (SAg) by
Externí odkaz:
https://doaj.org/article/0f99cf8186544981adcce632e3337375
Autor:
Silvia Sapienza, Valentina Tedeschi, Barbara Apicella, Anna Pannaccione, Carmela Russo, Maria Josè Sisalli, Giorgia Magliocca, Stefania Loffredo, Agnese Secondo
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 273, Iss , Pp 116104- (2024)
Increased risk of neurodegenerative diseases has been envisaged for air pollution exposure. On the other hand, environmental risk factors, including air pollution, have been suggested for Amyotrophic Lateral Sclerosis (ALS) pathomechanism. Therefore,
Externí odkaz:
https://doaj.org/article/ce4221280da74e40b4b7ca7de9632e54
Autor:
Giorgia Magliocca, Emilia Esposito, Michele Tufano, Ilaria Piccialli, Valentina Rubino, Valentina Tedeschi, Maria Jose Sisalli, Flavia Carriero, Giuseppina Ruggiero, Agnese Secondo, Lucio Annunziato, Antonella Scorziello, Anna Pannaccione
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 999 (2024)
Parkinson’s disease (PD), the second most common neurodegenerative disease in the elderly, is characterized by selective loss of dopaminergic neurons and accumulation of α-synuclein (α-syn), mitochondrial dysfunction, Ca2+ dyshomeostasis, and neu
Externí odkaz:
https://doaj.org/article/f925091609084f1dab5ec54ad4aa09df
Autor:
Ilaria Piccialli, Francesca Greco, Giovanni Roviello, Maria Josè Sisalli, Valentina Tedeschi, Antonia di Mola, Nicola Borbone, Giorgia Oliviero, Vincenzo De Feo, Agnese Secondo, Antonio Massa, Anna Pannaccione
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115745- (2023)
Amyloid β 1–42 (Aβ1–42) protein aggregation is considered one of the main triggers of Alzheimer’s disease (AD). In this study, we examined the in vitro anti-amyloidogenic activity of the isoindolinone derivative 3-(3-oxoisoindolin-1-yl)pentan
Externí odkaz:
https://doaj.org/article/2b87979d9b2c497db12fc7b6d53fed45
Autor:
Valentina Tedeschi, Antonio Vinciguerra, Maria Josè Sisalli, Giuseppe Pignataro, Agnese Secondo
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106020- (2023)
Lysosomal function and organellar Ca2+ homeostasis become dysfunctional in Stroke causing disturbances in autophagy, the major process for the degradation of abnormal protein aggregates and dysfunctional organelles. However, the role of autophagy in
Externí odkaz:
https://doaj.org/article/adb8f6a410224cbd8db3a730988e6448
Autor:
Tiziana Petrozziello, Francesca Boscia, Valentina Tedeschi, Anna Pannaccione, Valeria de Rosa, Angela Corvino, Beatrice Severino, Lucio Annunziato, Agnese Secondo
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background The cycad neurotoxin beta-methylamino-l-alanine (L-BMAA), one of the environmental trigger factor for amyotrophic lateral sclerosis/Parkinson-dementia complex (ALS/PDC), may cause neurodegeneration by disrupting organellar Ca2+ ho
Externí odkaz:
https://doaj.org/article/906b0019fd284affb8f235f1bb97c477
Autor:
Benedetta Mattorre, Valentina Tedeschi, Giorgia Paldino, Maria Teresa Fiorillo, Fabiana Paladini, Rosa Sorrentino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The Endoplasmic Reticulum Aminopeptidase 1 and 2 (ERAP1 and ERAP2) and Insulin Regulated Aminopeptidase (IRAP) are three M1 zinc metalloproteases whose role in antigen processing is the refining of peptidome either in the Endoplasmic reticulum (ERAP1
Externí odkaz:
https://doaj.org/article/e2e8869bb6ff4dc5a93abc3cb7055714
Autor:
Simone Marcella, Barbara Apicella, Agnese Secondo, Francesco Palestra, Giorgia Opromolla, Renato Ciardi, Valentina Tedeschi, Anne Lise Ferrara, Carmela Russo, Maria Rosaria Galdiero, Leonardo Cristinziano, Luca Modestino, Giuseppe Spadaro, Alfonso Fiorelli, Stefania Loffredo
Publikováno v:
Environment International, Vol 166, Iss , Pp 107395- (2022)
The anthropogenic particulate matter (PM), suspended air dust that can be inhaled by humans and deposited in the lungs, is one of the main pollutants in the industrialized cities atmosphere. Recent studies have shown that PM has adverse effects on re
Externí odkaz:
https://doaj.org/article/e23bf1b1a7a94670b533020b71749cc1
Autor:
Ilaria Piccialli, Valentina Tedeschi, Lucia Caputo, Stefano D’Errico, Roselia Ciccone, Vincenzo De Feo, Agnese Secondo, Anna Pannaccione
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alzheimer’s disease (AD) is a chronic, complex neurodegenerative disorder mainly characterized by the irreversible loss of memory and cognitive functions. Different hypotheses have been proposed thus far to explain the etiology of this devastating
Externí odkaz:
https://doaj.org/article/35848766f0684592a84238c11a8c0ff2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple Sclerosis (MS) is a neurodegenerative autoimmune disorder of the central nervous system (CNS) characterized by the recruitment of self-reactive T lymphocytes, mainly inflammatory T helper (Th) cell subsets. Once recruited within the CNS, inf
Externí odkaz:
https://doaj.org/article/1c0bdac853e3416d85575453c49c66ee